Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mahbubul H. Shihan"'
Autor:
Mahbubul H. Shihan, Sachin Sharma, Carson Cable, Vijaya Prathigudupu, Alina Chen, Aras N. Mattis, Jennifer Y. Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Hepatic fibrosis is driven by the activation of hepatic stellate cells (HSCs). The Hippo pathway and its effectors, YAP and TAZ, are key regulators of HSC activation and fibrosis. However, there is a lack of mechanistic understanding of YAP/
Externí odkaz:
https://doaj.org/article/da53c32d081d422e9d8ac3a11c1158ca
Autor:
Amy Yu, Carson Cable, Sachin Sharma, Mahbubul H. Shihan, Aras N. Mattis, Izolda Mileva, Yusuf A. Hannun, Caroline C. Duwaerts, Jennifer Y. Chen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Non-alcoholic fatty liver disease (NAFLD) is a common cause of liver disease worldwide, and is characterized by the accumulation of fat in the liver. Non-alcoholic steatohepatitis (NASH), an advanced form of NAFLD, is a leading cause of liver transpl
Externí odkaz:
https://doaj.org/article/6725eb13e1904aa59cea259f043342fe
Autor:
Mahbubul H. Shihan, Samuel G. Novo, Yan Wang, Dean Sheppard, Amha Atakilit, Thomas D. Arnold, Nicole M. Rossi, Adam P. Faranda, Melinda K. Duncan
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Fibrotic posterior capsular opacification (PCO), a major complication of cataract surgery, is driven by transforming growth factor–β (TGF-β). Previously, αV integrins were found to be critical for the onset of TGF-β–mediated PCO in vivo; howe
Externí odkaz:
https://doaj.org/article/c9e28f11d62b44629c539707f7d2cffa
Autor:
Samuel G. Novo, Adam P. Faranda, Mahbubul H. Shihan, Yan Wang, Ananya Garg, Melinda K. Duncan
Publikováno v:
Cells, Vol 11, Iss 21, p 3456 (2022)
Cataracts are treated by lens fiber cell removal followed by intraocular lens (IOL) implantation into the lens capsule. While effective, this procedure leaves behind numerous lens epithelial cells (LECs) which undergo a wound healing response that fr
Externí odkaz:
https://doaj.org/article/b0d483f93e3a4dae86cd8e54fa866fbb
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100916- (2021)
Western blotting (WB), enzyme-linked immunosorbent assay (ELISA) and flow cytometry (FC) have long been used to assess and quantitate relative protein expression in cultured cells and tissue samples. However, WB and ELISA have limited ability to mean
Externí odkaz:
https://doaj.org/article/f7cd18ae19d14d628255d3cf4b843cad
Autor:
Amy Yu, Carson Cable, Mahbubul H. Shihan, Sachin Sharma, Aras N. Mattis, Izolda Mileva, Yusuf A. Hannun, Caroline C. Duwaerts, Jennifer Y. Chen
1)ABSTRACTNonalcoholic fatty liver disease (NAFLD) is a common cause of liver disease worldwide, and is characterized by the accumulation of fat in the liver. Nonalcoholic steatohepatitis (NASH), an advanced form of NAFLD, is a leading cause of liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdbfd5d708aacd6cfd766da13ee04d1f
https://doi.org/10.1101/2022.07.10.499388
https://doi.org/10.1101/2022.07.10.499388
Publikováno v:
Exp Eye Res
The transcriptome of mammalian tissues differs between males and females, and these differences can change across the lifespan, likely regulating known sexual dimorphisms in disease prevalence and severity. Cataract, the most prevalent disease of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d12fab507b411303e95c4153f55f7a0
https://europepmc.org/articles/PMC8595539/
https://europepmc.org/articles/PMC8595539/
Publikováno v:
Curr Med Res Opin
PURPOSE: To determine cataract surgeon viewpoints on the efficacy of available therapies/preventatives for two common sequelae of cataract surgery; inflammation and posterior capsular opacification (PCO). METHODS: Cataract surgeons practicing worldwi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab475121534b62d8943c1ca621deda60
https://doi.org/10.1080/03007995.2019.1647012
https://doi.org/10.1080/03007995.2019.1647012
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss, Pp 100916-(2021)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Western blotting (WB), enzyme-linked immunosorbent assay (ELISA) and flow cytometry (FC) have long been used to assess and quantitate relative protein expression in cultured cells and tissue samples. However, WB and ELISA have limited ability to mean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f396db8167c0c5a42387cb6e94f5af1
http://www.sciencedirect.com/science/article/pii/S2405580821000108
http://www.sciencedirect.com/science/article/pii/S2405580821000108
Autor:
Melinda K. Duncan, Mallika Kanwar, Erin E. Jackson, Mahbubul H. Shihan, Yan Wang, Adam Faranda
Publikováno v:
Matrix Biol
Fibrotic posterior capsular opacification (PCO), one of the major complications of cataract surgery, occurs when lens epithelial cells (LCs) left behind post cataract surgery (PCS) undergo epithelial to mesenchymal transition, migrate into the optica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6c69541c35f80e9e1a78880d499256
https://pubmed.ncbi.nlm.nih.gov/32173580
https://pubmed.ncbi.nlm.nih.gov/32173580