Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Mahboubeh Eghbali"'
Autor:
Mahboubeh Eghbali-Webb, Hyeon-Woo Lee
Publikováno v:
Journal of Molecular and Cellular Cardiology. 30:1359-1368
The role of female hormones in the prevalence of cardiac diseases are recognized but not fully explored. Proliferation of cardiac fibroblasts, the cellular origin of the extracellular matrix proteins, growth factors and cytokines in the heart, is an
Publikováno v:
Molecular and Cellular Biochemistry. 172:195-198
Cardiac fibroblasts constitute greater than 90% of non-myocyte cells in the heart. Because they are responsible for synthesis of components of the extracellular matrix, growth factors and cytokines in the myocardium, they play an important role in no
Publikováno v:
Journal of Molecular and Cellular Cardiology. 28:1921-1929
Cardiac fibroblasts constitute greater than 90% of the non-myocyte cells in the heart. Previously, it was established that cardiac fibroblasts are predisposed to transformation into a phenotype with muscle-specific features and that transforming grow
Publikováno v:
Journal of Molecular and Cellular Cardiology. 28:33-42
It is established that thyroxine-induced ventricular hypertrophy is associated with downregulation of collagen type I gene expression and increased collagen turnover in the ventricular tissue. The present study was undertaken to test the hypothesis t
Autor:
Mahboubeh Eghbali, Ann Abraham, Edward Frizell, E. Helene Sage, Iwata Ozaki, Mark A. Zern, Shu Ling Liu
Publikováno v:
Hepatology. 21:847-854
SPARC (secreted protein, acidic and rich in cysteine)--also known as osteonectin, BM-40, and 43K glycoprotein--is secreted by endothelial cells and fibroblasts in response to culture shock. SPARC has been found in association with tissues undergoing
Autor:
Mahboubeh Eghbali
Publikováno v:
Cardiovascular Pathology. 2:199-205
This review is the summary of our findings on collagen gene expression and regulation in ventricular myocardium in experimental animal models of cardiac hypertrophy and in cardiac fibroblasts in response to hormonal stimuli. Cardiac fibrosis, or accu
Autor:
Jianling Yao, Mahboubeh Eghbali
Publikováno v:
Cardiovascular Research. 26:603-607
The aim was to study the effect of thyroid hormone on collagen gene expression in the myocardium of the tight skin mouse (TSK), a genetic model of myocardial fibrosis.Heterozygous male (TSK/+) (n = 20) and normal (+/+) homozygous mice (n = 20), 1.5-2
Publikováno v:
Cell & Tissue Research. 265:353-359
In the heart of the adult rat, fibroblasts are mainly responsible for the synthesis and deposition of the collagenous matrix. Because these cells in vitro may serve as an important model system for studies of collagen metabolism in heart tissue, we h
Publikováno v:
Circulation Research. 69:483-490
Cardiac fibroblasts are responsible for synthesis and deposition of fibrillar collagen types I and III. Transforming growth factor-beta 1 (TGF-beta 1) has been proved to increase collagen biosynthesis in various systems, both in vivo and in vitro. We
Publikováno v:
Proceedings of the National Academy of Sciences. 88:795-799
Cardiac fibroblasts are mainly responsible for the synthesis of major extracellular matrix proteins in the heart, including fibrillar collagen types I and III and fibronectin. In this report we show that these cells, when stimulated by transforming g