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pro vyhledávání: '"Mahboubeh Daneshpajooh"'
Autor:
Petter Vikman, Mahboubeh Daneshpajooh, Madhusudhan Bysani, Charlotte Ling, Annika Bagge, Hindrik Mulder, Lena Eliasson, Emilia Ottosson Laakso, Karl Bacos
Publikováno v:
Diabetologia
Aims/hypothesis Pancreatic beta cell dysfunction is a prerequisite for the development of type 2 diabetes. Histone deacetylases (HDACs) may affect pancreatic endocrine function and glucose homeostasis through alterations in gene regulation. Our aim w
Publikováno v:
Acta Diabetologica
Aims It has in recent years been established that epigenetic changes contribute to β-cell dysfunction and type 2 diabetes (T2D). For example, we have showed that the expression of histone deacetylase 7 (HDAC7) is increased in pancreatic islets of in