Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Mahboob ul Hussain"'
Autor:
Umar Mehraj, Irfan Ahmad Mir, Mahboob ul Hussain, Mustfa Alkhanani, Nissar Ahmad Wani, Manzoor Ahmad Mir
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Doxorubicin is a commonly used chemotherapeutic agent to treat several malignancies, including aggressive tumors like triple-negative breast cancer. It has a limited therapeutic index owing to its extreme toxicity and the emergence of drug resistance
Externí odkaz:
https://doaj.org/article/6f9bd18847f04528a908b4472a76cccc
Autor:
Mohd Younus Bhat, Irfan Ahmad Mir, Mahboob Ul Hussain, Laishram Rajendrakumar Singh, Tanveer Ali Dar
Publikováno v:
Journal of biomolecular structuredynamics.
Trimethylamine N-oxide (TMAO) is generally accumulated by organisms and cells to cope with denaturing effects of urea/hydrodynamic pressure on proteins and can even reverse misfolded or aggregated proteins so as to sustain proteostasis. However, most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f263ec1d0ddfe2d0cc09b2aca8596db4
https://pubmed.ncbi.nlm.nih.gov/35315738
https://pubmed.ncbi.nlm.nih.gov/35315738
Breast cancer (BC) is a global public health burden, constituting the highest cancer incidence in women worldwide. Connexins 43 proteins propagate intercellular communication, gap junction intercellular communication (GJIC), remarkably expressed in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd231a3c71fa78cc5c37004ed4f71cf
https://doi.org/10.5772/intechopen.97582
https://doi.org/10.5772/intechopen.97582
Publikováno v:
Gene Reports. 12:310-316
Purpose Sonic hedgehog (SHH) protein is a morphogen which functions as a ligand for the SHH pathway, has significant roles during embryonic development. Aberrant activation of the SHH pathway via ligand overexpression has been implicated in many canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ed5e12bf5ba2140c76d8d321da938c
https://doi.org/10.1016/j.genrep.2018.07.017
https://doi.org/10.1016/j.genrep.2018.07.017
Autor:
Mahboob Ul Hussain, Saife Niaz
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 101:29-38
GW182 proteins interact directly with the argonaute proteins and constitute key components of miRNA repressor complexes (miRISC) in metazoans. As argonautes are insufficient for silencing they recruit the GW182 s that act as scaffold proteins inducin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6172c87d8804403a4b89dd3b83505eee
https://doi.org/10.1016/j.biocel.2018.05.009
https://doi.org/10.1016/j.biocel.2018.05.009
Publikováno v:
Cell and Tissue Research. 371:213-222
Connexin 43 (Cx43) is a gap junction protein expressed in various tissues and organs of vertebrates. Besides functioning as a gap junction, Cx43 also regulates diverse cellular processes like cell growth and differentiation, cell migration, cell surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c333dbafa2cb38363ad99d590572ad0a
https://doi.org/10.1007/s00441-017-2736-3
https://doi.org/10.1007/s00441-017-2736-3
Autor:
Mahboob Ul Hussain, Rehana Ismail
Publikováno v:
Biochimie. 139:38-45
Purpose Astrocytes cope-up the hypoxia conditions by up regulating the activity of the enzymes catalyzing the irreversible steps of the glycolytic pathway. The phosphofructokinase1 (PFK1), which converts fructose-6-phosphate to fructose-1, 6-bisphosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b392ac3bc2de3e0b94bc713f16ad4631
https://doi.org/10.1016/j.biochi.2017.05.012
https://doi.org/10.1016/j.biochi.2017.05.012
Publikováno v:
Cancer Biomarkers. 18:389-395
BACKGROUND Hippo-LATS pathway is involved in regulating multiple phenotypes. TAZ (transcriptional co-activator with PDZ-binding motif) is a prominent proto-oncogene of this developmental pathway. Elevated TAZ expression has been observed in many canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c8250591420064f0df804789bf41d3
https://doi.org/10.3233/cbm-160263
https://doi.org/10.3233/cbm-160263
Autor:
Syed Mudassar, Mohammad Akbar Shah, Majeed Dar, Mosin S. Khan, Showkat A Malik, Mahboob Ul Hussain, Sheikh Muzamil Shafi
Publikováno v:
Pathology & Oncology Research. 24:207-214
Large tumor suppressor (LATS) is an important member of the Hippo pathway which can regulate organ size and cell proliferation. However, very little is known about the expression and clinical significance of LATS in lung cancer especially from this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784f162e8e68b9e6af1be057e927860f
https://doi.org/10.1007/s12253-017-0225-3
https://doi.org/10.1007/s12253-017-0225-3