Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mahboob Hossain Qureshi"'
Publikováno v:
The Journal of Immunology. 202:119.22-119.22
RSV infection in early life predisposes to asthma later in life. Role of aberrant immune responses to childhood viral infections is well documented. Involvement of myeloid (mDC) and plasmacytoid (pDC) Dendritic Cells (DC) and Natural Killer T-cells (
Autor:
Kazutoshi Shibuya, Satomi Yara, Kaori Uezu, Kazuyoshi Kawakami, Tiantuo Zhang, Yuki Kinjo, Yoshinobu Koguchi, Atsushi Saito, Mahboob Hossain Qureshi, Shiro Naoe
Publikováno v:
Microbiology and Immunology. 46:181-186
To elucidate the role of the beta2 integrin family of adhesion molecules in the disseminated infection of Cryptococcus neoformans from the lung to the central nervous system, we examined the effects of monoclonal antibodies (mAbs) against CD11a, CD11
Autor:
Yoshinobu Koguchi, Akiko Miyazato, Akio Nishizawa, Atsushi Saito, Mahboob Hossain Qureshi, Kazuyoshi Kawakami, Hideo Nariuchi, Satomi Yara, Yuki Kinjo
Publikováno v:
Microbiology and Immunology. 44:1033-1041
In the present study, we examined the effect of soluble CD4 (sCD4) on host resistance and delayed-type hypersensitivity (DTH) response to Cryptococcus neoformans using a novel mutant mouse that exhibits a defect in the expression of membrane-bound CD
Autor:
Yoshinobu Koguchi, Mahboob Hossain Qureshi, Yuki Kinjo, Kazuyoshi Kawakami, Satomi Yara, Koari Uezu, Atsushi Saito
Publikováno v:
Microbiology and Immunology. 44:1043-1050
In the present study, we examined whether natural killer (NK) cells have direct fungicidal activity against Cryptococcus neoformans. Splenic NK cells were obtained from SCID mice and stimulated with a combination of interleukin (IL)-12 and IL-18 in f
Autor:
Shizuo Akira, Akiko Miyazato, Mahboob Hossain Qureshi, Masashi Kurimoto, Yoshinobu Koguchi, Atsushi Saito, Kazuyoshi Kawakami, Satomi Yara, Kiyoshi Takeda, Yuki Kinjo
Publikováno v:
FEMS Microbiology Letters. 186:121-126
Using interleukin (IL)-18 deficient (IL-18(-/-)) mice, we examined the role of IL-18 in the host resistance and Th1 response against infection with Cryptococcus neoformans. Fungal clearance in the lung was reduced in IL-18(-/-) mice, although there w
Autor:
Kiyoshi Takeda, Mahboob Hossain Qureshi, Tiantuo Zhang, Shizuo Akira, Masashi Kurimoto, Yoshinobu Koguchi, Satomi Yara, Kazuyoshi Kawakami, Atsushi Saito
Publikováno v:
FEMS Immunology & Medical Microbiology. 27:191-200
We previously demonstrated that interleukin (IL)-12 protected mice against fatal pulmonary infection with a highly virulent strain of Cryptococcus neoformans, which correlated well with the production of interferon (IFN)-gamma as well as IL-18 in the
Autor:
Mahboob Hossain Qureshi, Tiantuo Zhang, Masashi Kurimoto, Yoshinobu Koguchi, Kazuyoshi Kawakami, Atsushi Saito, Qifeng Xie
Publikováno v:
Cellular Immunology. 197:55-61
We examined the role of interleukin (IL)-4 in host resistance against infection with Cryptococcus neoformans. First, we examined the effects of a neutralizing anti-IL-4 monoclonal antibody (mAb) on survival of mice infected intratracheally with this
Autor:
Mahboob Hossain Qureshi, Atsushi Saito, Yoshinobu Koguchi, Kazuyoshi Kawakami, Kazutoshi Nakajima
Publikováno v:
FEMS Microbiology Letters. 175:87-94
In the present study, we examined the in vitro effect of Cryptococcus neoformans on the production of interleukin-12 (IL-12) and IL-10 by murine macrophages. At a dose of 1 x 10(5), 1 x 10(6) or 1 x 10(7) ml-1, a highly virulent strain of C. neoforma
Autor:
Haruki Okamura, Tiantuo Zhang, Kazuyoshi Kawakami, Atsushi Saito, Masashi Kurimoto, Yoshinobu Koguchi, Mahboob Hossain Qureshi
Publikováno v:
Cellular Immunology. 193:9-16
We have recently demonstrated that two IFN-gamma-inducing cytokines, interleukin (IL)-12 and IL-18, synergistically induced the fungicidal activity of mouse peritoneal exudate cells (PEC) against Cryptococcus neoformans through NK cell production of
Publikováno v:
Clinical and Experimental Immunology. 115:491-497
SUMMARYWe examined the in vitro effect of Candida albicans on NO production by macrophages. Candida albicans suppressed not only NO production but also expression of inducible NO synthase (iNOS) mRNA by murine IFN-γ and bacterial LPS-stimulated peri