Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mahashweta Basu"'
Autor:
Gurmannat Kalra, Danielle Lenz, Dunia Abdul-Aziz, Craig Hanna, Mahashweta Basu, Brian R. Herb, Carlo Colantuoni, Beatrice Milon, Madhurima Saxena, Amol C. Shetty, Ronna Hertzano, Ramesh A. Shivdasani, Seth A. Ament, Albert S.B. Edge
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113421- (2023)
Summary: We explore the changes in chromatin accessibility and transcriptional programs for cochlear hair cell differentiation from postmitotic supporting cells using organoids from postnatal cochlea. The organoids contain cells with transcriptional
Externí odkaz:
https://doaj.org/article/41e88d4f61974a9aa88109f9cfc014da
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1433-1443 (2021)
Abstract Heterogeneous treatment effect (HTE) analysis focuses on examining varying treatment effects for individuals or subgroups in a population. For example, an HTE‐informed understanding can critically guide physicians to individualize the medi
Externí odkaz:
https://doaj.org/article/e940d1e300514556aecec097f696b4a6
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009427 (2021)
Complex age-associated phenotypes are caused, in part, by an interaction between an individual's genotype and age. The mechanisms governing such interactions are however not entirely understood. Here, we provide a novel transcriptional mechanism-base
Externí odkaz:
https://doaj.org/article/06509c22b6af47abb4ab47515d734856
Autor:
Mohor Biplab Sengupta, Mahashweta Basu, Sourav Iswarari, Kiran Kumar Mukhopadhyay, Krishna Pada Sardar, Biplab Acharyya, Pradeep K Mohanty, Debashis Mukhopadhyay
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110885 (2014)
Recovery of sensory and motor functions following traumatic spinal cord injury (SCI) is dependent on injury severity. Here we identified 49 proteins from cerebrospinal fluid (CSF) of SCI patients, eight of which were differentially abundant among two
Externí odkaz:
https://doaj.org/article/81868b80ecf14dafb9edd473b477b37f
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64838 (2013)
Disease-causing mutations usually change the interacting partners of mutant proteins. In this article, we propose that the biological consequences of mutation are directly related to the alteration of corresponding protein protein interaction network
Externí odkaz:
https://doaj.org/article/d6ad250b99774ea08dbffa9afa836f59
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1433-1443 (2021)
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 11, Pp 1433-1443 (2021)
Heterogeneous treatment effect (HTE) analysis focuses on examining varying treatment effects for individuals or subgroups in a population. For example, an HTE‐informed understanding can critically guide physicians to individualize the medical treat
Autor:
Jimmy Olusakin, Gautam Kumar, Mahashweta Basu, Cali A. Calarco, Megan E. Fox, Jason B. Alipio, Catherine Haga, Makeda D. Turner, Asaf Keller, Seth A. Ament, Mary Kay Lobo
Use of the synthetic opioid fentanyl increased ∼300% in the last decade, including among women of reproductive ages. Adverse neonatal outcomes and long-term behavioral disruptions are associated with perinatal opioid exposure. Our previous work dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a8e8fce1c6b29ff4335ddf8e678ea6e
https://doi.org/10.1101/2022.11.18.517129
https://doi.org/10.1101/2022.11.18.517129
Autor:
Gessynger Morais-Silva, Rianne R. Campbell, Hyungwoo Nam, Mahashweta Basu, Marco Pagliusi, Megan E. Fox, C. Savio Chan, Sergio D. Iñiguez, Seth Ament, Nathan Cramer, Marcelo Tadeu Marin, Mary Kay Lobo
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience.
Altered activity of the ventral pallidum (VP) underlies disrupted motivation in stress and drug exposure. The VP is a very heterogeneous structure composed of many neuron types with distinct physiological properties and projections. Neuronal PAS 1-po
Autor:
Shana Golden, Ramesh Chandra, Yonatan M. Kupchik, Gal Elyasaf, Mary Kay Lobo, Nimrod Bernat, Michel Engeln, Hyungwoo Nam, Mahashweta Basu, Seth A. Ament, Tal Odesser, Rianne Campbell
The ventral pallidum (VP) is central to reward seeking and withdrawal from drugs of abuse. A characteristic of the VP is the diversity of its projection targets. Yet, it remains unknown whether different VP projections also differ in other aspects, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c18989391fcc9d0cfe81a4223f7aa43
https://doi.org/10.1101/2021.11.15.468637
https://doi.org/10.1101/2021.11.15.468637
Autor:
Marcelo Tadeu Marin, Sergio D. Iñiguez, Rianne Campbell, Gessynger Morais-Silva, Marco Pagliusi, Hyungwoo Nam, Seth A. Ament, Savio Chan, Mary Kay Lobo, Mahashweta Basu, Megan E. Fox
Altered activity of the ventral pallidum (VP) underlies disrupted motivation in stress and drug exposure. The VP is a very heterogeneous structure comprised of many neuron types with distinct physiological properties and projections. Neuronal PAS 1-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d27867346dc18d7a52c878ba6adbc7ba
https://doi.org/10.1101/2021.10.27.466188
https://doi.org/10.1101/2021.10.27.466188