Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mahalingam S Sundaram"'
Autor:
Anilkumar C Nirvanappa, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Hanumappa Ananda, Alexey Yu Sukhorukov, Muthu K Shanmugam, Mahalingam S Sundaram, Siddaiah Chandra Nayaka, Kesturu S Girish, Arunachalam Chinnathambi, M E Zayed, Sulaiman Ali Alharbi, Gautam Sethi, Basappa, Kanchugarakoppal S Rangappa
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175659 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0163209.].
Externí odkaz:
https://doaj.org/article/76a24ca338674d728121e710c710551d
Autor:
Anilkumar C Nirvanappa, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Hanumappa Ananda, Alexey Yu Sukhorukov, Muthu K Shanmugam, Mahalingam S Sundaram, Siddaiah Chandra Nayaka, Kesturu S Girish, Arunachalam Chinnathambi, M E Zayed, Sulaiman Ali Alharbi, Gautam Sethi, Basappa, Kanchugarakoppal S Rangappa
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163209 (2016)
Aberrant activation of nuclear factor kappa B (NF-κB) has been linked with the pathogenesis of several proinflammatory diseases including number of cancers and inflammatory bowel diseases. In the present work, we evaluated the anticancer activity of
Externí odkaz:
https://doaj.org/article/fb530b59bd574ed7af390d2936ac020b
Autor:
Manoj Paul, Mahadevappa Hemshekhar, Ram M Thushara, Mahalingam S Sundaram, Somanathapura K NaveenKumar, Shivanna Naveen, Sannaningaiah Devaraja, Kumar Somyajit, Robert West, Basappa, Siddaiah C Nayaka, Uzma I Zakai, Ganesh Nagaraju, Kanchugarakoppal S Rangappa, Kempaiah Kemparaju, Kesturu S Girish
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127558 (2015)
Thrombocytopenia in methotrexate (MTX)-treated cancer and rheumatoid arthritis (RA) patients connotes the interference of MTX with platelets. Hence, it seemed appealing to appraise the effect of MTX on platelets. Thereby, the mechanism of action of M
Externí odkaz:
https://doaj.org/article/7b90458664c440bd92ea3aa86f9c5083
Autor:
Nirvanappa C Anilkumar, Mahalingam S Sundaram, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Krishna C Bulusu, Julian E Fuchs, Kesturu S Girish, Andreas Bender, Basappa, Kanchugarakoppal S Rangappa
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131896 (2015)
Drugs such as necopidem, saripidem, alpidem, zolpidem, and olprinone contain nitrogen-containing bicyclic, condensed-imidazo[1,2-α]pyridines as bioactive scaffolds. In this work, we report a high-yield one pot synthesis of 1-(2-methyl-8-aryl-substit
Externí odkaz:
https://doaj.org/article/94a75cf564f24b0189ba5f78380f401d
Autor:
Hanumantharayappa Bharathkumar, Mahalingam S Sundaram, Swamy Jagadish, Shardul Paricharak, Mahadevappa Hemshekhar, Daniel Mason, Kempaiah Kemparaju, Kesturu S Girish, Basappa, Andreas Bender, Kanchugarakoppal S Rangappa
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102759 (2014)
Glycoside hydrolases catalyze the selective hydrolysis of glycosidic bonds in oligosaccharides, polysaccharides, and their conjugates. β-glucosidases occur in all domains of living organisms and constitute a major group among glycoside hydrolases. O
Externí odkaz:
https://doaj.org/article/11079c6114884d9198e14337f2e1fea5
Autor:
Venkatachalaiah Srinivasa, Mahalingam S Sundaram, Sebastian Anusha, Mahadevappa Hemshekhar, Siddaiah Chandra Nayaka, Kempaiah Kemparaju, Basappa, Kesturu S Girish, Kanchugarakoppal S Rangappa
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106364 (2014)
The classical antivenom therapy has appreciably reduced snakebite mortality rate and thus is the only savior drug available. Unfortunately, it considerably fails to shield the viper bite complications like hemorrhage, local tissue degradation and nec
Externí odkaz:
https://doaj.org/article/c1ccf4da85c64a63a68d3a0aace19953
Autor:
Kodagahalli S Rakesh, Swamy Jagadish, Ajjampura C Vinayaka, Mahadevappa Hemshekhar, Manoj Paul, Ram M Thushara, Mahalingam S Sundaram, Toreshettahally R Swaroop, Chakrabhavi D Mohan, Basappa, Marilinganadoddi P Sadashiva, Kempaiah Kemparaju, Kesturu S Girish, Kanchugarakoppal S Rangappa
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107182 (2014)
Thrombocytopenia is a serious issue connected with the pathogenesis of several human diseases including chronic inflammation, arthritis, Alzheimer's disease, cardiovascular diseases (CVDs) and other oxidative stress-associated pathologies. The indisc
Externí odkaz:
https://doaj.org/article/71b42da3762949dbae4ffd9fd325e5f1
Autor:
Kesturu S. Girish, Kempaiah Kemparaju, Somanathapura K. NaveenKumar, Mahalingam S. Sundaram, Mahadevappa Hemshekhar
Publikováno v:
Biochemical and Biophysical Research Communications. 491:183-191
Cell-free hemoglobin (Hb), a well-known marker of intravascular hemolysis, is eventually oxidized to methemoglobin (MtHb). Elevated levels of MtHb have been noted, alongside depleted levels of platelets, in several hemolytic diseases. The current stu
Autor:
Kesturu S. Girish, Mahadevappa Hemshekhar, Kurnegala Manikanta, T. N. Ramesh, Manoj S. Paul, S. Naveen, Kempaiah Kemparaju, Mahalingam S. Sundaram
Publikováno v:
Toxicology in Vitro. 63:104743
Curcumin, a major bioactive component of turmeric (Curcuma longa), is known for its multiple health benefits. Curcumin as such is a mixture of its analogs: bisdemethoxycurcumin (BDMC)-3%, and demethoxycurcumin (DMC)-17%. Although the effect of curcum
Autor:
G. Suresh Kumar, Mahaboobkhan Rasool, K.S. Girish, Manoj Kumar Neog, Kempaiah Kemparaju, Mahadevappa Hemshekhar, Mahalingam S. Sundaram
Publikováno v:
Phytomedicine. 64:152924
Background Arthritis is a common degenerative joint disease characterized by deterioration of articular cartilage, subchondral bone, and associated with immobility, pain and inflammation. The incessant action of reactive oxygen species (ROS) during p