Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mahadevan Gajendiran"'
Publikováno v:
Neuroscience Letters. 308:201-205
The synaptic transmission and intrinsic membrane properties of spiny neurons in rat neostriatum were studied after unilateral dopamine depletion using in vivo intracellular recording and staining techniques. Two to four weeks after dopamine denervati
Publikováno v:
NeuroReport. 7:513-516
THE relative roles of D1 and D2 dopamine (DA) receptors in mediating apomorphine (APO)-induced changes in the spinal reflex was investigated. Low doses of APO, a DA receptor agonist (0.2 mg kg -1 , i.v.), depressed the monosynaptic mass reflex (MMR)
Publikováno v:
Neuroscience Letters. 158:217-220
The possible modulatory role of D1 dopamine receptors on the excitability of lumbar spinal Renshaw cells was studied in anesthetized rats spinalized at T4 level. Burst responses elicited by single electrical shocks to ipsilateral ventral roots L6 (fr
Autor:
Mahadevan Gajendiran
Publikováno v:
Brain research bulletin. 75(5)
The purpose of the present study was to investigate the 5-HT 2C receptor-mediated effects on the spinal monosynaptic mass reflex activities and also its functional interactions with 5-HT 1A receptors in anesthetized, acutely spinalized mammalian adul
Autor:
Mahadevan Gajendiran
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 31(7)
The effects of 7- and 21-day haloperidol treatment on the spinal serotonergic system were examined in vivo in acutely spinalized adult rats. Intravenous administration of a selective 5-HT 2A/2C receptor agonist, (±)-2,5-Dimethoxy-4-iodoamphetamine h
Autor:
Mahadevan Gajendiran
Publikováno v:
Neuroreport. 17(12)
Serotonin modulates neurotransmission at synapses between various spinal neurons and, thus, may either facilitate or depress the information processed in the circuits and ultimately modulate the final motor output. A possible neuromodulatory role of
Autor:
Nigel T. Maidment, Mahadevan Gajendiran, Marie-Françoise Chesselet, Jie Shen, Matthew S. Goldberg, Sheila M. Fleming, Anushree Bhatnagar, Larry C. Ackerson, Gloria J. Klapstein, Edward G. Meloni, Michael Levine, Carlos Cepeda, Bryan L. Roth, James Palacino, Nanping Wu, Hoa A. Lam
Publikováno v:
The Journal of biological chemistry. 278(44)
Loss-of-function mutations in parkin are the major cause of early-onset familial Parkinson's disease. To investigate the pathogenic mechanism by which loss of parkin function causes Parkinson's disease, we generated a mouse model bearing a germline d
Publikováno v:
Neuroreport. 8(11)
SEROTONERGIC influence on spinal monosynaptic transmission and the desensitization of spinal 5-HT 1A receptors following a single pretreatment with a 5-HT 1A ligand were examined in vivo in acutely spinalized adult rats. Administration of a selective
Publikováno v:
Journal of Neuroscience Research; Apr2005, Vol. 80 Issue 2, p203-210, 8p