Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis.

Autor: Licht-Mayer S; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Campbell GR; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Canizares M; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Mehta AR; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Gane AB; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., McGill K; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Ghosh A; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Fullerton A; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Menezes N; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Dean J; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK., Dunham J; Department of Neuroscience, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, OH44195, USA., Al-Azki S; Barts and The London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK., Pryce G; Barts and The London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK., Zandee S; Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4SB, UK., Zhao C; Wellcome Trust-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0AW, UK., Kipp M; Institute of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057, Rostock, Germany., Smith KJ; Department of Neuroinflammation, The UCL Queen Square Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK., Baker D; Barts and The London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK., Altmann D; Faculty of Medicine, Department of Medicine, Hammersmith Campus, London, UK., Anderton SM; Centre for Inflammation Research, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4SB, UK., Kap YS; Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands., Laman JD; Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.; Dept. Biomedical Sciences of Cells and Systems and MS Center Noord Nederland (MSCNN), University Medical Center Groningen, University Groningen, Groningen, The Netherlands., Hart BA'; Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.; Dept. Biomedical Sciences of Cells and Systems and MS Center Noord Nederland (MSCNN), University Medical Center Groningen, University Groningen, Groningen, The Netherlands.; Department Anatomy and Neuroscience, Amsterdam University Medical Center (V|UMC|), Amsterdam, Netherlands., Rodriguez M; Department of Neurology and Immunology, Mayo College of Medicine and Science, Rochester, MN, MN55905, USA., Watzlawick R; Department of Neurosurgery, Freiburg University Medical Center, Freiburg, Germany., Schwab JM; Spinal Cord Injury Medicine, Department of Neurology, The Ohio State University, Wexner Medical Center, Columbus, USA., Carter R; Centre for Cardiovascular Science, Queens Medical Research Institute, 47 Little France Crescent, Edinburgh, UK., Morton N; Centre for Cardiovascular Science, Queens Medical Research Institute, 47 Little France Crescent, Edinburgh, UK., Zagnoni M; Centre for Microsystems and Photonics, Electronic and Electrical Engineering, University of Strathclyde, Glasgow, UK., Franklin RJM; Wellcome Trust-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0AW, UK., Mitchell R; Centre for Discovery Brain Science, Edinburgh Medical School, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK., Fleetwood-Walker S; Centre for Discovery Brain Science, Edinburgh Medical School, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK., Lyons DA; Centre for Discovery Brain Science, Edinburgh Medical School, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK., Chandran S; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK., Lassmann H; Department of Neuroimmunology, Center for Brain Research, Medical University Vienna, Spitalgasse 4, 1090, Vienna, Austria., Trapp BD; Department of Neuroscience, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, OH44195, USA., Mahad DJ; Centre for Clinical Brain Sciences, University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, UK. don.mahad@ed.ac.uk.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2020 Aug; Vol. 140 (2), pp. 143-167. Date of Electronic Publication: 2020 Jun 22.

Minocycline prevents early age-related cognitive decline in a mouse model of intellectual disability caused by ZBTB18/RP58 haploinsufficiency.

Autor: Tanaka, Tomoko^1,2 (AUTHOR) tanaka-tm@igakuken.or.jp, Hirai, Shinobu¹ (AUTHOR), Manabe, Hiroyuki³ (AUTHOR), Endo, Kentaro⁴ (AUTHOR), Shimbo, Hiroko¹ (AUTHOR), Nishito, Yasumasa⁴ (AUTHOR), Horiuchi, Junjiro⁴ (AUTHOR), Yoshitane, Hikari² (AUTHOR), Okado, Haruo¹ (AUTHOR) okado-hr@igakuken.or.jp

Publikováno v: Journal of Neuroinflammation. 10/12/2024, Vol. 21 Issue 1, p1-13. 13p.

Exercise-induced changes in gait kinematics in multiple sclerosis with minimal neurological disability.

Autor: Andreopoulou G; Centre for Health, Activity and Rehabilitation Research, Queen Margaret University, Musselburgh, UK., Mercer TH; Centre for Health, Activity and Rehabilitation Research, Queen Margaret University, Musselburgh, UK., Enriquez JG; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Justin M; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, UK., MacLeod N; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, UK., Harrison E; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, UK., Mahad DJ; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK; Anne Rowling Regenerative Neurology Clinic, University of Edinburgh, UK. Electronic address: don.mahad@ed.ac.uk., van der Linden ML; Centre for Health, Activity and Rehabilitation Research, Queen Margaret University, Musselburgh, UK. Electronic address: mvanderlinden@qmu.ac.uk.

Publikováno v: Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2021 Jan; Vol. 47, pp. 102630. Date of Electronic Publication: 2020 Nov 19.

Myelin modulates the process of isoflurane anesthesia through the regulation of neural activity.

Autor: Wang, Xu^1,2,3 (AUTHOR), Yi, Rulan^1,2,3,4 (AUTHOR), Liang, Xiaoling^1,2,3 (AUTHOR), Zhang, Ning^1,2,3 (AUTHOR), Zhong, Fuwang^1,2,3 (AUTHOR), Lu, Yali^1,2,3 (AUTHOR), Chen, Wenjia^1,2,3 (AUTHOR), Yu, Tian^1,2,3,4 (AUTHOR), Zhang, Linyong⁴ (AUTHOR), Wang, Haiying^1,2,3,4 (AUTHOR) dllwanghaiyin@163.com, Zhou, Liang^1,2,3,4 (AUTHOR) zllzlj@zju.edu.cn

Publikováno v: CNS Neuroscience & Therapeutics. Aug2024, Vol. 30 Issue 8, p1-16. 16p.

Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.

Autor: Klotz L; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany. luisa.klotz@ukmuenster.de., Eschborn M; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Lindner M; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Liebmann M; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Herold M; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Janoschka C; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Torres Garrido B; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Schulte-Mecklenbeck A; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Gross CC; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Breuer J; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Hundehege P; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Posevitz V; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Pignolet B; CRC-SEP, Neurosciences Department, Toulouse University Hospital and INSERM U1043 - CNRS UMR 5282, Centre de Physiopathologie Toulouse-Purpan, Université Toulouse III, 31300 Toulouse, France., Nebel G; University of Münster, Institute of Molecular Cell Biology, 48149 Münster, Germany., Glander S; University of Münster, Department of Genetic Epidemiology, 48149 Münster, Germany., Freise N; University of Münster, Department of Immunology, 48149 Münster, Germany., Austermann J; University of Münster, Department of Immunology, 48149 Münster, Germany., Wirth T; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Campbell GR; University of Edinburgh, Centre for Clinical Brain Sciences, EH8 9YL Edinburgh, UK., Schneider-Hohendorf T; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Eveslage M; University of Münster, Institute of Biostatistics and Clinical Research, 48149 Münster, Germany., Brassat D; CRC-SEP, Neurosciences Department, Toulouse University Hospital and INSERM U1043 - CNRS UMR 5282, Centre de Physiopathologie Toulouse-Purpan, Université Toulouse III, 31300 Toulouse, France., Schwab N; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Loser K; University Hospital Münster, Department of Dermatology, 48149 Münster, Germany., Roth J; University of Münster, Department of Immunology, 48149 Münster, Germany., Busch KB; University of Münster, Institute of Molecular Cell Biology, 48149 Münster, Germany., Stoll M; University of Münster, Department of Genetic Epidemiology, 48149 Münster, Germany.; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, 6229 ER Maastricht, Netherlands., Mahad DJ; University of Edinburgh, Centre for Clinical Brain Sciences, EH8 9YL Edinburgh, UK., Meuth SG; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany., Turner T; Sanofi Genzyme, Cambridge, MA 02142, USA., Bar-Or A; Center for Neuroinflammation and Experimental Therapeutics and Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Wiendl H; University Hospital Münster, Department of Neurology with Institute of Translational Neurology, 48149 Münster, Germany.; Brain and Mind Centre, Medical Faculty, University of Sydney, Sydney, Camperdown, NSW 2050, Australia.

Publikováno v: Science translational medicine [Sci Transl Med] 2019 May 01; Vol. 11 (490).