Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mahabub Maraj Alam"'
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 413-415 (2023)
Externí odkaz:
https://doaj.org/article/7698245cb46c41d782b1e0a7563b5dd8
Autor:
Peng Jiang, Mahabub Maraj Alam
Publikováno v:
Cell Regeneration, Vol 11, Iss 1, Pp 1-4 (2022)
Abstract Human-mouse chimeras offer advantages for studying the pathophysiology of human cells in vivo. Chimeric mouse brains have been created by engrafting human fetal tissue- or pluripotent stem cell-derived progenitor cells into the neonatal mous
Externí odkaz:
https://doaj.org/article/0731f0e9c3e74dd5a2bc97e0064f2975
Autor:
Prashant Tarale, Mahabub Maraj Alam
Publikováno v:
Inflammopharmacology. 30:821-842
Colony Stimulating Factor-1 (CSF-1)/Colony Stimulating Factor-1 Receptor (CSF-1R) signaling axis plays an essential role in the development, maintenance, and proliferation of macrophage lineage cells. Within the central nervous system, CSF-1R signali
Publikováno v:
Stem cell reports. 17(11)
Immunodeficient mice are widely used in human stem cell transplantation research. Recombination activating gene 1 (Rag1) deletion results in immunodeficiency and leads to accelerated aging in zebrafish with increased cytosolic accumulation of lipofus
Autor:
Mengmeng Jin, Ranjie Xu, Le Wang, Mahabub Maraj Alam, Ziyuan Ma, Sining Zhu, Alessandra C. Martini, Azadeh Jadali, Matteo Bernabucci, Ping Xie, Kelvin Y. Kwan, Zhiping P. Pang, Elizabeth Head, Ying Liu, Ronald P. Hart, Peng Jiang
Publikováno v:
Cell Stem Cell. 29:1135-1153.e8
Microglia are critical in brain development and Alzheimer's disease (AD) etiology. Down syndrome (DS) is the most common genetic developmental disorder and risk factor for AD. Surprisingly, little information is available on the impact of trisomy of
Autor:
Xinjun Zhu, Ramkumar Mathur, Hwajeong Lee, Tingting Huang, Edward C. Lee, Yuan Liao, Mahabub Maraj Alam, Jeffrey Shen, Shannon Morgan, Yunfei Huang, Xiao-Feng Zhao
Publikováno v:
Mucosal Immunology. 12:612-623
Intestinal fibrosis is an excessive proliferation of myofibroblasts and deposition of collagen, a condition frequently seen in Crohn's disease (CD). The mechanism underlying myofibroblast hyper-proliferation in CD needs to be better understood. In th
Autor:
Mengmeng Jin, Ranjie Xu, Mahabub Maraj Alam, Ziyuan Ma, Sining Zhu, Le Wang, Alessandra C. Martini, Matteo Bernabucci, Ping Xie, Kelvin Kwan, Zhiping P. Pang, Ying Liu, Elizabeth Head, Ronald P. Hart, Peng Jiang
Publikováno v:
SSRN Electronic Journal.
Autor:
Xinjun Cindy Zhu, Matthew A. Adamo, Joseph E. Mazurkiewicz, Ramkumar Mathur, Mahabub Maraj Alam, Xiao-Feng Zhao, Yuan Liao, Yunfei Huang, Paul J. Feustel
Publikováno v:
J Neurosci
Excessive activation of mammalian target of rapamycin (mTOR) signaling is epileptogenic in genetic epilepsy. However, the exact role of microglial mTOR in acquired epilepsy remains to be clarified. In the present study, we found that mTOR is strongly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96da5a52a3209ad17fded8aba9a6e243
https://europepmc.org/articles/PMC7531547/
https://europepmc.org/articles/PMC7531547/
Publikováno v:
Journal of visualized experiments : JoVE. (151)
Significant studies have been carried out to understand effective management of intestinal fibrosis. However, the lack of better knowledge of fibrosis has hindered the development of a preventative drug. Primarily, finding a suitable animal model is
Autor:
Joseph E. Mazurkiewicz, Yannick Poitelon, Paul J. Feustel, Sophie Belin, Matthew A. Adamo, Ramkumar Mathur, Yuan Liao, Mahabub Maraj Alam, Xiao-Feng Zhao, Sarah E. McCallum, Yunfei Huang, Xinjun Cindy Zhu
Publikováno v:
eNeuro
Excessive activation of mTOR in microglia impairs CNS homeostasis and causes severe epilepsy. Autophagy constitutes an important part of mTOR signaling. The contribution of microglial autophagy to CNS homeostasis and epilepsy remains to be determined