Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Maha S. Almutairi"'
Publikováno v:
BMC Chemistry, Vol 13, Iss 1, Pp 1-17 (2019)
Abstract Recent studies have suggested that aldose reductase inhibition preferentially inhibits the growth of cancer cells. However, the investigations of this issue are not many. Novel nine substituted- 4′-iminospiro[indoline-3,3′-[1,2,5] thiadi
Externí odkaz:
https://doaj.org/article/fab90957846844ab866a0bb26777e3eb
Autor:
Wagdy M. Eldehna, Reem I. Al-Wabli, Maha S. Almutairi, Adam B. Keeton, Gary A. Piazza, Hatem A. Abdel-Aziz, Mohamed I. Attia
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 867-878 (2018)
In connection with our research program on the development of novel indolin-2-one-based anticancer candidates, herein we report the design and synthesis of different series of hydrazonoindolin-2-ones 3a-e, 5a-e, 7a-c, and 10a-l. The synthesised deriv
Externí odkaz:
https://doaj.org/article/5bdec6d70379489db17eeaf64167abda
Autor:
Maha S. Almutairi, Areej N. Al Suwayyid, Amal Aldarwesh, Omaima M. Aboulwafa, Mohamed I. Attia
Publikováno v:
Molecules, Vol 25, Iss 7, p 1553 (2020)
The preparation of certain 2-(2-oxo-2H-chromen-4-yl)-N-substituted acetamides IIIa–h was planned as a step in the development of new modified nonsteroidal antiestrogens. The purity of target compounds IIIa–h was checked by thin-layer chromatograp
Externí odkaz:
https://doaj.org/article/c4f5f951394847829280d588bd270011
Autor:
Maha S. Almutairi, Gehan H. Hegazy, Mogedda E. Haiba, Hamed I. Ali, Nagy M. Khalifa, Abd El-mohsen M. Soliman
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 12, Pp 22580-22603 (2014)
Herein, novel hybrid compounds of celecoxib and 2-aminoanthraquinone derivatives have been synthesized using condensation reactions of celecoxib with 2-aminoanthraquinone derivatives or 2-aminoanthraquinon with celecoxib derivatives. Celecoxib was re
Externí odkaz:
https://doaj.org/article/42922305ee29456f830a5a4af2e83822
Publikováno v:
Molecules, Vol 18, Iss 10, Pp 12208-12221 (2013)
Anti-Candida activities of certain new oximes 4a–d and their respective aromatic esters 5a–l are reported. The tested compounds 4a–d and 5a–l exhibited better anti-Candida profiles than fluconazole. Compound 5j, namely (E)-3-(1H-imidazol-1-yl
Externí odkaz:
https://doaj.org/article/86aad92b8b434be7bce583159d208d62
Autor:
Maha S. Almutairi, Azza S. Zakaria, Reem I. Al-Wabli, I. Hubert Joe, Ali S. Abdelhameed, Mohamed I. Attia
Publikováno v:
Molecules, Vol 23, Iss 5, p 1043 (2018)
N-(2-{[2-(1H-Indol-2-ylcarbonyl)hydrazinyl](oxo)acetyl}phenyl)acetamides (5a–h) and N-[2-(2-{[2-(acetylamino)phenyl](oxo)acetyl}hydrazinyl)-2-oxoethyl]-1H-indole-2-carboxamides (5i–l) were synthesized and characterized with different analytical t
Externí odkaz:
https://doaj.org/article/249a351ad2f0429e87423c134b53b580
Autor:
Mohamed I. Attia, Hazem A. Ghabbour, Maha S. Almutairi, Soraya W. Ghoneim, Hatem A. Abdel-Aziz, Hoong-Kun Fun
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
Synthesis and characterization of (1E)-1-(4-chlorophenyl)-N-hydroxy-3-(1H-imidazol-1-yl)propan-1-imine (4) are reported. X-ray crystal structure of the title oxime 4 confirmed its assigned (E)-configuration. The compound crystallizes in the monoclini
Externí odkaz:
https://doaj.org/article/969a96dec8a04401bc325e8145d0f256
Autor:
Mohamed I. Attia, Hazem A. Ghabbour, Aida A. El-Azzouny, Omar A. Al-Deeb, Maha S. Almutairi, Hoong-Kun Fun
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
Synthesis, spectroscopic characterization and X-ray crystal structure of a new (2E)-2-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]-N-phenylhydrazinecarboxamide (4) are reported. The stereochemistry of the title compound 4, C19H19N5O, about the imine bo
Externí odkaz:
https://doaj.org/article/35c171a3157b4c28800018407c4e8a84
Autor:
Maha S. Almutairi, Ali A. El-Emam, Nasser R. El-Brollosy, Mohammed Said-Abdelbaky, Santiago García-Granda
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 7, Pp o2247-o2248 (2012)
The title molecule, C17H20N2O, is a functionalized hydrazine with benzoyl and adamantyl substituents attached to the two hydrazine N atoms. In the crystal, molecules are linked via N—H...N hydrogen bonds, forming chains propagating along the a-axis
Externí odkaz:
https://doaj.org/article/b7ad0b0f719949a5b6516c3ead9a6512
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 3, Pp o627-o627 (2012)
The title compound, C12H13N3O, exists in an E configuration with respect to the C=N bond [1.285 (2) Å]. The imidazole ring forms a dihedral angle of 75.97 (10)° with the phenyl ring. In the crystal, molecules are linked via O—H...N and C—H...N
Externí odkaz:
https://doaj.org/article/d27fd8e0ef554ea9adeeb4c99ccdd942