Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maha Kosa"'
Autor:
Justin T. Hoffman, Cho-Ming Loi, Melissa O’Gorman, Anna Plotka, Maha Kosa, Anna Jakubowska, Diane D. Wang
Publikováno v:
Cancer Research. 76:LB-196
Introduction: Itraconazole is recognized by the FDA and the EMA as a strong inhibitor of CYP3A and is included in both agencies published drug-drug interaction (DDI) guidances on the list of preferred interacting drugs for use in CYP3A inhibition stu
Autor:
L. Musick, S. H. Reich, Bhasker V. Shetty, H. Dawson, Krzysztof Appelt, K. K. Lewis, B.‐W. Wu, D. Andrada, Stephanie Webber, D. Kahil, Michael Melnick, D. K. Gehlhaar, Jay F. Davies, Maha Kosa, L. J. Jun. Mitchell, Anthony J. Trippe, Nguyen Dzuy Nguyen Dzuy
Publikováno v:
ChemInform. 27
Autor:
Ru Zhou, Stephen E. Webber, Thomas J. Prins, Joseph T. Marakovits, Rose Ann Ferre, Edward L. Brown, Caroline A. Lee, James E. V. Harr, Peter S. Dragovich, Tove Tuntland, Benjamin J. Burke, Amy K. Patick, Clifford E. Ford, Shella A. Fuhrman, Paul A. Rejto, Thomas F. Hendrickson, Maha Kosa, Stephen T. Worland, James W. Meador, David A. Matthews
Publikováno v:
Journal of medicinal chemistry. 42(7)
The structure-based design, chemical synthesis, and biological evaluation of various human rhinovirus (HRV) 3C protease (3CP) inhibitors which incorporate P1 lactam moieties in lieu of an L-glutamine residue are described. These compounds are compris
Autor:
Heather Dawson, Mitchell Lennert J, Kathy K. Lewis, Stephanie Webber, Dominic Andrada, B.‐W. Wu, Krzysztof Appelt, Anthony J. Trippe, Dan K. Gehlhaar, Deborah Kahil, Dzuy T. Nguyen, Jay F. Davies, Bhasker V. Shetty, L. Musick, Reich Siegfried Heinz, Melnick Michael J, Maha Kosa
Publikováno v:
Journal of medicinal chemistry. 39(14)
A series of potent nonpeptide inhibitors of the HIV protease have been identified. Using the structure of compound 3 bound to the HIV protease, bis tertiary amide inhibitor 9 was designed and prepared. Compound 9 was found to be about 17 times more p