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Acute Hemodynamic Effects of Conivaptan, a Dual V 1A and V 2 Vasopressin Receptor Antagonist, in Patients With Advanced Heart Failure

Autor: Francoise Chanoine, William B. Smith, Jalal K. Ghali, Maha Ghazzi, Grady H. Hendrix, Milton L. Pressler, James E. Udelson, Christopher A. Painchaud, Ignatius Thomas, Marvin A. Konstam, Paulina Selaru

Publikováno v: Circulation. 104:2417-2423

Background Arginine vasopressin may contribute to abnormalities in hemodynamics and fluid balance in heart failure through its actions on V 1A (vascular and myocardial effects) and V 2 receptors (renal effects). Inhibiting the action of vasopressin m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee01e07a62869953d8c62d869c45622
https://doi.org/10.1161/hc4501.099313

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Rationale for use of an exercise end point and design for the ADVANCE (A Dose evaluation of a Vasopressin ANtagonist in CHF patients undergoing Exercise) trial

Autor: Maha Ghazzi, Milton Pressler, Alexis Serikoff, Paulina Selaru, Stuart D. Russell, David A. Pyne, Kenneth D. Massey, Andrew J.S. Coats

Publikováno v: American heart journal. 145(1)

Background Exercise intolerance is a primary characteristic of chronic congestive heart failure. Exercise testing is therefore widely used to evaluate the degree of functional impairment, prognosis of underlying cardiac disease, and response to treat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c806efe8ad555c7013f72f6a8fbe29e
https://pubmed.ncbi.nlm.nih.gov/12514672

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