Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mahé Bouquet"'
Autor:
Karin Wildi, Sebastiano Maria Colombo, Daniel McGuire, Carmen Ainola, Silver Heinsar, Noriko Sato, Kei Sato, Keibun Liu, Mahé Bouquet, Emily Wilson, Margaret Passmore, Kieran Hyslop, Samantha Livingstone, Marianna Di Feliciantonio, Wendy Strugnell, Chiara Palmieri, Jacky Suen, Gianluigi Li Bassi, John Fraser
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Mortality and morbidity of Acute Respiratory Distress Syndrome (ARDS) are largely unaltered. A possible new approach to treatment of ARDS is offered by the discovery of inflammatory subphenotypes. In an ovine model of ARDS phenotypes, matchi
Externí odkaz:
https://doaj.org/article/fb7511b8f0ca4607b108b2f5330a6221
Autor:
Karin Wildi, Samantha Livingstone, Carmen Ainola, Sebastiano Maria Colombo, Silver Heinsar, Noriko Sato, Kei Sato, Mahé Bouquet, Emily Wilson, Gabriella Abbate, Margaret Passmore, Kieran Hyslop, Keibun Liu, Xiaomeng Wang, Chiara Palmieri, Louise E. See Hoe, Jae-Seung Jung, Katrina Ki, Christian Mueller, John Laffey, Paolo Pelosi, Gianluigi Li Bassi, Jacky Suen, John Fraser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Whilst the presence of 2 subphenotypes among the heterogenous Acute Respiratory Distress Syndrome (ARDS) population is becoming clinically accepted, subphenotype-specific treatment efficacy has yet to be prospectively tested. We investigated
Externí odkaz:
https://doaj.org/article/d047360fec9b4fd8b2322f230102a4fb
Autor:
Karin Wildi, Kieran Hyslop, Jonathan Millar, Samantha Livingstone, Margaret R. Passmore, Mahé Bouquet, Emily Wilson, Gianluigi LiBassi, John F. Fraser, Jacky Y. Suen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundThe discovery of biological subphenotypes in acute respiratory distress syndrome (ARDS) might offer a new approach to ARDS in general and possibly targeted treatment, but little is known about the underlying biology yet. To validate our rec
Externí odkaz:
https://doaj.org/article/72fe8cee2d554bb78e63878a7cdf389c
Autor:
Katrina K. Ki, Margaret R. Passmore, Chris H. H. Chan, Maximilian V. Malfertheiner, Jonathon P. Fanning, Mahé Bouquet, Jonathan E. Millar, John F. Fraser, Jacky Y. Suen
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving modality used to manage cardiopulmonary failure refractory to conventional medical and surgical therapies. Despite advances in ECMO equipment, bleeding and thrombosis rem
Externí odkaz:
https://doaj.org/article/7ae044f5301d48e59fa15eb526bd783e
Autor:
Varun Karnik, Sebastiano Maria Colombo, Leah Rickards, Silver Heinsar, Louise E. See Hoe, Karin Wildi, Margaret R. Passmore, Mahe Bouquet, Kei Sato, Carmen Ainola, Nicole Bartnikowski, Emily S. Wilson, Kieran Hyslop, Kris Skeggs, Nchafatso G. Obonyo, Charles McDonald, Samantha Livingstone, Gabriella Abbate, Andrew Haymet, Jae-Seung Jung, Noriko Sato, Lynnette James, Benjamin Lloyd, Nicole White, Chiara Palmieri, Mark Buckland, Jacky Y. Suen, David C. McGiffin, John F. Fraser, Gianluigi Li Bassi
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Open-lung ventilation during cardiopulmonary bypass (CPB) in patients undergoing heart transplantation (HTx) is a potential strategy to mitigate postoperative acute respiratory distress syndrome (ARDS). We utilized an ovine HTx model to inve
Externí odkaz:
https://doaj.org/article/5ec2089cb8ca435584c95f51876bc537
Autor:
Nchafatso G. Obonyo, Sainath Raman, Jacky Y. Suen, Kate M. Peters, Minh-Duy Phan, Margaret R. Passmore, Mahe Bouquet, Emily S. Wilson, Kieran Hyslop, Chiara Palmieri, Nicole White, Kei Sato, Samia M. Farah, Lucia Gandini, Keibun Liu, Gabriele Fior, Silver Heinsar, Shinichi Ijuin, Sun Kyun Ro, Gabriella Abbate, Carmen Ainola, Noriko Sato, Brooke Lundon, Sofia Portatadino, Reema H. Rachakonda, Bailey Schneider, Amanda Harley, Louise E. See Hoe, Mark A. Schembri, Gianluigi Li Bassi, John F. Fraser
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-20 (2024)
Abstract Background Escherichia coli is the most common cause of human bloodstream infections and bacterial sepsis/septic shock. However, translation of preclinical septic shock resuscitative therapies remains limited mainly due to low-fidelity of av
Externí odkaz:
https://doaj.org/article/c03348cdf8dc412a96c6356e9237ed0f
Autor:
Sacha Rozencwajg, Silver Heinsar, Karin Wildi, Jae‐Seung Jung, Sebastiano Maria Colombo, Chiara Palmieri, Kei Sato, Carmen Ainola, Xiaomeng Wang, Gabriella Abbate, Noriko Sato, Wayne B. Dyer, Samantha Livingstone, Leticia Helms, Nicole Bartnikowski, Mahe Bouquet, Margaret R. Passmore, Kieran Hyslop, Bruno Vidal, Janice D. Reid, Daniel McGuire, Emily S. Wilson, Indrek Rätsep, Roberto Lorusso, Matthieu Schmidt, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Differential hypoxaemia (DH) is common in patients supported by femoral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and can cause cerebral hypoxaemia. To date, no models have studied the direct impact of flow on cerebral dam
Externí odkaz:
https://doaj.org/article/46782239fa8b45baae781849abd36da3
Autor:
Pierre Sonveaux, Celine Forez, Patrick Van Der Smissen, Sabrina Klotz, Mahé Bouquet, Christophe E. Pierreux, Pierre J. Courtoy, Anne-Christine Hick, Tamara Copetti, Jean-François Collet, Anne-Sophie Delmarcelle, Olivier Feron
Publikováno v:
Developmental Biology. 381:227-240
The thyroid is a highly vascularized endocrine gland, displaying a characteristic epithelial organization in closed spheres, called follicles. Here we investigate how endothelial cells are recruited into the developing thyroid and if they control gla
Autor:
Jennifer Bolsée, Anne-Sophie Delmarcelle, Lieve Umans, Susana M. Chuva de Sousa Lopes, Mylah Villacorte, Frédéric P. Lemaigre, Guido T. Bommer, Patrick Henriet, An Zwijsen, Samuel Refetoff, Christophe E. Pierreux, Pascale Lemoine, Patrick Van Der Smissen, Pierre J. Courtoy, Manon Lernoux, Takako Sasaki, Mahé Bouquet
Publikováno v:
Development, 143(11), 1958-1970
Thyroid follicles, the functional units of the thyroid gland, are delineated by a monolayer of thyrocytes resting on a continuous basement membrane. Developmental mechanisms whereby follicles are formed by reorganization of a non-structured mass of n
Autor:
Wayne B. Dyer, Gabriela Simonova, Sara Chiaretti, Mahe Bouquet, Rebecca Wellburn, Silver Heinsar, Carmen Ainola, Karin Wildi, Kei Sato, Samantha Livingstone, Jacky Y. Suen, David O. Irving, John-Paul Tung, Gianluigi li Bassi, John F. Fraser
Publikováno v:
Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background Fluid resuscitation is the standard treatment to restore circulating blood volume and pressure after massive haemorrhage and shock. Packed red blood cells (PRBC) are transfused to restore haemoglobin levels. Restoration of microci
Externí odkaz:
https://doaj.org/article/ccfd5282a1c449e6a362e9fb6d086cc3