Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Magnus Winnerstam"'
Autor:
Anne Månsson Kvarnhammar, Niina Veitonmäki, Karin Hägerbrand, Anna Dahlman, Karin Enell Smith, Sara Fritzell, Laura von Schantz, Mia Thagesson, Doreen Werchau, Kristine Smedenfors, Maria Johansson, Anna Rosén, Ida Åberg, Magnus Winnerstam, Eva Nyblom, Karin Barchan, Christina Furebring, Per Norlén, Peter Ellmark
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background The CTLA-4 blocking antibody ipilimumab has demonstrated substantial and durable effects in patients with melanoma. While CTLA-4 therapy, both as monotherapy and in combination with PD-1 targeting therapies, has great potential in
Externí odkaz:
https://doaj.org/article/ac146a36143540ed83d59ae4ac9773f4
Autor:
Sara Fritzell, Anne Månsson Kvarnhammar, Karin Enell Smith, Laura Von Schantz, Mia Thagesson, Doreen Werchau, Anna Rosén, Per Norlén, Karin Hägerbrand, Eva Nyblom, Peter Ellmark, Niina Veitonmäki, Christina Furebring, Kristine Smedenfors, Maria Johansson, Karin Barchan, Magnus Winnerstam, Ida Åberg, Anna Dahlman
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Background The CTLA-4 blocking antibody ipilimumab has demonstrated substantial and durable effects in patients with melanoma. While CTLA-4 therapy, both as monotherapy and in combination with PD-1 targeting therapies, has great potential in many ind
Autor:
Karin Enell Smith, Per Norlén, Maria C Johansson, Sara Fritzell, Magnus Winnerstam, Christina Furebring, Peter Ellmark, Ida Åberg, Mattias Levin, Anne Månsson Kvarnhammar
Publikováno v:
Cancer Research. 79:4077-4077
ATOR-1144 is a human CTLA-4 x GITR bispecific IgG1 antibody generated by fusing a high affinity CTLA-4 binder, derived by FIND® optimization of the CTLA-4 binding domain of CD86, to an agonistic GITR antibody isolated from the human antibody library