Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Magnus Widegren"'
Autor:
Jovana Nazor, Michael D. Clay, Magnus Widegren, Sheela Muley, Jeff Colbeck, David Entwistle, Ben Mijts, S. M. Palanivel, Amritha Appaswami, Michael Vogel, Shiwei Song, Jack Liang, Yong Koy Bong, Steven J. Collier, Jun Zhu, Derek Smith, Karthik Narayanaswamy, Ryan Fong, Robert John Wilson, Xiyun Zhang
Publikováno v:
The Journal of Organic Chemistry. 83:7453-7458
A wild-type Baeyer–Villiger monooxygenase was engineered to overcome numerous liabilities in order to mediate a commercial oxidation of pyrmetazole to esomeprazole, using air as the terminal oxidant in an almost exclusively aqueous reaction matrix.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b32c05079cdfed9f74dea5e4c5b6138
https://doi.org/10.1021/acs.joc.8b00468
https://doi.org/10.1021/acs.joc.8b00468
Autor:
Mirosława Gładysz, Maciej Rogacki, Łukasz Dudek, Kinga Michalik, Jolanta Mazurek, Marcin Leś, Aleksandra Poczkaj, Peter Littlewood, Krzysztof Brzózka, Aniela Golas, Stefan Chmielewski, Justyna Jabłońska, Raghuram Tangirala, Magnus Widegren, Kamil Kuś, Urszula Głowniak-Kwitek, Nilesh Gaud, Izabela Strojny, Katarzyna Dziedzic, Arkadiusz Białas, Magdalena Zawadzka, Grzegorz Ćwiertnia
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A799-A799
BackgroundSTimulator of INterferon Genes (STING) is a key signaling protein involved in activation of the immune system in response to self-DNA. In recent years, STING signaling has been demonstrated to play a major role in activating the antitumor i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c00502def4d384b672f8d068e4507738
https://doi.org/10.1136/jitc-2021-sitc2021.764
https://doi.org/10.1136/jitc-2021-sitc2021.764
Autor:
Magnus Widegren, Hayley Jackman, Jean-Philippe Crochard, Melissa Birch, Kevin Meldrum, Stephen Challenger, Amy Luan, David Sebastien Fradet, Neil McDowall, Charles M. Gordon, Evelyn Madigan, Stephen Yeo
Publikováno v:
Organic Process Research & Development. 15:1172-1177
The development and implementation of a robust process for the manufacture of metric ton quantities of the α2δ ligand imagabalin hydrochloride 4 is described. Key aspects of the synthesis include a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0675fe296642f354a99b5be242772fb
https://doi.org/10.1021/op2001639
https://doi.org/10.1021/op2001639
Autor:
Melanie Dietz, Mikael Katz, Magnus Widegren, Torbjörn Frejd, Marie-Francoise Gorwa-Grauslund, Bärbel Hahn-Hägerdal, Annika Friberg
Publikováno v:
Synthesis. 2006:3527-3530
The cyclisation conditions for the formation of bicyclo[2.2.2]octan-2,6-di one (1) from 3-substituted cyclohexanones 2 and 3 have been re-investigated. Use of a medium consisting of isobutyric anhydride and trifluoroacetic acid resulted in a simplifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a5be72604f9f9873c98e73d8f8d985
https://doi.org/10.1055/s-2006-942532
https://doi.org/10.1055/s-2006-942532
Autor:
Mark McLaughlin, Magnus Widegren, Antonio Ramirez, Paul Richardson, Andrei Zlota, Trevor Laird
Publikováno v:
Organic Process Research & Development; Jan2012, Vol. 16 Issue 1, p3-10, 8p