Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Magnus Thörn"'
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1612 (2008)
BACKGROUND: Naturally occurring thymus derived regulatory T cells (Tregs) are central in the maintenance of self-tolerance. The transcription factor FOXP3 is crucial for the suppressive activity of Tregs and is considered the most specific marker for
Externí odkaz:
https://doaj.org/article/fdb5fa8635684c219be997d73973abe3
Autor:
Lars Öhberg, Magnus Thörn, E. Eriksson, Katrine Riklund, Janos Vasko, Börje Ljungberg, Amir Sherif
Publikováno v:
BJU International. 109:1134-1139
Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? This is the first presented results and second publication on detection of tumour-dr ...
Publikováno v:
European Urology. 58:105-111
Background Expected 2-yr survival for patients with urothelial urinary bladder cancer (UBC) with lymph node involvement (pN2) is 20%, regardless of standard neoadjuvant/adjuvant oncologic treatment. Tumor-reactive lymphocytes are present in sentinel
Autor:
Ola Winqvist, Magnus Thörn, Kjell Dahl, Mona Karlsson, Tobias Dagöö, Sven Enerbäck, Per Marits
Publikováno v:
Annals of Surgical Oncology
Background Despite optimal surgical treatment and modern adjuvant therapies, 50% of patients diagnosed with colorectal cancer die within 5 years. Immunotherapy offers an appealing complement to traditional chemotherapy, with possible long-term protec
Publikováno v:
European Journal of Gastroenterology & Hepatology. 20:985-988
Objective Mesenteric lymph nodes may play a crucial role in the pathogenesis of human inflammatory bowel disease. We have used the sentinel node technique to analyze mesenteric lymph nodes draining inflammatory lesions sentinel nodes and correspondin
Publikováno v:
The Journal of Immunology. 181:2878-2886
The execution of appropriate gene expression patterns during immune responses is of eminent importance where CpG methylation has emerged as an essential mechanism for gene silencing. We have charted the methylation status of regulatory elements in th
Publikováno v:
Journal of Immunological Methods. 334:122-133
In colon cancer the presence of metastases in the regional lymph nodes is an important prognostic factor. Currently, examination is based on histological and immunohistochemical evaluations of lymph node sections. However, these methods are time-cons
Publikováno v:
European Urology. 50:83-91
To explore the feasibility of performing lymphoscintigraphy combined with computed tomography (CT) for preoperative detection of sentinel lymph nodes in patients with invasive bladder cancer.Six consecutive patients scheduled for radical cystectomy u
Autor:
Per Marits, Magnus Thörn, Ola Winqvist, Kjell Dahl, Patrik Larsson, Mona Karlsson, Alkvin Wanders
Publikováno v:
British Journal of Cancer
The sentinel node is the first lymph node to receive lymphatic drainage from a tumour and is usually the first site of metastases. Today, the sentinel node is used for tumour staging. Here, we focus on its immunological role and investigate lymphocyt
Publikováno v:
European Urology. 49:59-70
Objective The lymphatic drainage from a tumour is received in the sentinel node where the immune system encounters tumour derived antigens. We investigated anti-tumoural lymphocyte function in sentinel nodes from patients with urinary bladder cancer.