CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

Autor: Jens S. Andersen, Mathieu Quinodoz, Reem Suleiman, Pernille Martens, Konstantinos Nikopoulos, André Brás Gonçalves, Pietro Farinelli, Carlo Rivolta, Catja Weiss, Sebastian Patzke, Beinta Biskopstø Joensen, Lotte B. Pedersen, Magnus Per Damsø Jeppesen, Sarah Kirstine Hasselbalch, Søren T. Christensen, Signe Krogh Ohlsen

Publikováno v: Gonçalves, A B, Hasselbalch, S K, Joensen, B B, Patzke, S, Martens, P, Ohlsen, S K, Quinodoz, M, Nikopoulos, K, Suleiman, R, Jeppesen, M P D, Weiss, C, Christensen, S T, Rivolta, C, Andersen, J S, Farinelli, P & Pedersen, L B 2021, ' CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels ', eLife, vol. 10, e63731 . https://doi.org/10.7554/eLife.63731
eLife
eLife, Vol 10 (2021)
Gonçalves, A B, Hasselbalch, S K, Joensen, B B, Patzke, S, Martens, P, Ohlsen, S K, Quinodoz, M, Nikopoulos, K, Suleiman, R, Jeppesen, M P D, Weiss, C, Christensen, S T, Rivolta, C, Andersen, J S, Farinelli, P & Pedersen, L B 2021, ' CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels ', eLife, vol. 10, e63731 . https://doi.org/10.7554/elife.63731

CEP78 is a centrosomal protein implicated in ciliogenesis and ciliary length control, and mutations in the CEP78 gene cause retinal cone-rod dystrophy associated with hearing loss. However, the mechanism by which CEP78 affects cilia formation is unkn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a7d2563e61fcb57025b1d22c78b416
https://findresearcher.sdu.dk:8443/ws/files/185246823/elife_63731_v2.pdf

CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

Autor: Konstantinos Nikopoulos, Beinta Biskopstø Joensen, Mathieu Quinodoz, Signe Krogh Ohlsen, Magnus Per Damsø Jeppesen, Catja Weiss, André Brás Gonçalves, Jens S. Andersen, Sarah Kirstine Hasselbalch, Lotte B. Pedersen, Reem Suleiman, Pietro Farinelli, Pernille Martens, Carlo Rivolta, Søren T. Christensen, Sebastian Patzke

CEP78 is a centrosomal protein implicated in ciliogenesis and ciliary length control, and mutations in the CEP78 gene cause retinal cone-rod dystrophy associated with hearing loss. However, the mechanism by which CEP78 affects cilia formation is unkn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb29c4dbd11aaeeea3bd03915a3571b1
https://doi.org/10.1101/2020.10.05.325936