Adoptive cell therapy with tumor-infiltrating lymphocytes in patients with metastatic ovarian cancer: a pilot study

Autor: Magnus Pedersen, Marie Christine Wulff Westergaard, Katy Milne, Morten Nielsen, Troels Holz Borch, Lars Grønlund Poulsen, Helle Westergren Hendel, Mia Kennedy, Gillian Briggs, Stacey Ledoux, Trine Jakobi Nøttrup, Pernille Andersen, Thomas Hasselager, Özcan Met, Brad H. Nelson, Marco Donia, Inge Marie Svane

Publikováno v: OncoImmunology, Vol 7, Iss 12 (2018)

Objective:Ovarian cancer (OC) is often diagnosed at an advanced stage with two thirds of patients experiencing recurrent disease with a poor prognosis. Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) has shown curative potential

Externí odkaz: https://doaj.org/article/be03c78a7de54047bd79130e1831c77a

Fast Portfolio Diversification

Autor: Magnus Pedersen

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e84379b17a56c2c0921a671c934b737
https://doi.org/10.2139/ssrn.4009041

Arctic Vision: Using Neural Networks for Ice Object Classification, and Controlling How They Fail

Autor: Ekaterina Kim, Ole-Magnus Pedersen

Publikováno v: Journal of Marine Science and Engineering, Vol 8, Iss 770, p 770 (2020)
Journal of Marine Science and Engineering
Volume 8
Issue 10

Convolutional neural networks (CNNs) have been shown to be excellent at performing image analysis tasks in recent years. Even so, ice object classification using close-range optical images is an area where their use has barely been touched upon, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c62e555eedc4938f2ef5387c3755fd1
https://www.mdpi.com/2077-1312/8/10/770

Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer

Autor: Lars Rønn Olsen, Brad H. Nelson, Sjoerd H. van der Burg, Morten Nielsen, Özcan Met, Saskia J. A. M. Santegoets, Magnus Pedersen, Troels Holz Borch, Inge Marie Svane, Marco Donia, Anders Handrup Kverneland, Katy Milne, Gitte Aasbjerg, Marie Christine Wulff Westergaard

Publikováno v: Kverneland, A H, Pedersen, M, Westergaard, M C W, Nielsen, M, Borch, T H, Olsen, L R, Aasbjerg, G, Santegoets, S J, van der Burg, S H, Milne, K, Nelson, B H, Met, Ö, Donia, M & Svane, I M 2020, ' Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer ', OncoTarget, vol. 11, no. 22, pp. 2092-2105 . https://doi.org/10.18632/oncotarget.27604
Oncotarget
Kverneland, A H, Pedersen, M, Wulff Westergaard, M C, Nielsen, M, Borch, T H, Olsen, L R, Aasbjerg, G, Santegoets, S J, van der Burg, S H, Milne, K, Nelson, B H, Met, Ö, Donia, M & Svane, I M 2020, ' Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer ', OncoTarget, vol. 11, no. 22, pp. 2092-2105 . https://doi.org/10.18632/oncotarget.27604

Immune therapy is a promising field within oncology but has been unsuccessful in ovarian cancer (OC). Still, there is rationale and evidence supporting immune therapy in OC. We investigated the potential for adoptive cell therapy (ACT) from in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59b418f23f195dfd05b12d4c8ef32b1
https://orbit.dtu.dk/en/publications/45f2e1bc-a069-411d-95dd-019d81706191

Correction: Tumour-reactive T cell subsets in the microenvironment of ovarian cancer

Autor: George Coukos, Thomas Hasselager, Magnus Pedersen, Christina Friese, Henrik Lajer, Chloe Chong, Marco Donia, Julie Westerlin Kjeldsen, Marie Christine Wulff Westergaard, Inge Marie Svane, Rikke Andersen, Michal Bassani-Sternberg

Solid malignancies are frequently infiltrated with T cells. The success of adoptive cell transfer (ACT) with expanded tumour-infiltrating lymphocytes (TILs) in melanoma warrants its testing in other cancer types. In this preclinical study, we investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2a59393df0c33c8de36b1d37b8074f
https://europepmc.org/articles/PMC6474273/