Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Magnus Lundqvist"'
Autor:
Niklas Berndt Thalén, Maximilian Karlander, Magnus Lundqvist, Helena Persson, Camilla Hofström, S. Pauliina Turunen, Magdalena Godzwon, Anna-Luisa Volk, Magdalena Malm, Mats Ohlin, Johan Rockberg
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Precise epitope determination of therapeutic antibodies is of great value as it allows for further comprehension of mechanism of action, therapeutic responsiveness prediction, avoidance of unwanted cross reactivity, and vaccine design. The g
Externí odkaz:
https://doaj.org/article/e8c8e0ec47704c01a51d5a3138a80a18
Autor:
Mei Ding, Rajneesh Malhotra, Tomas Ottosson, Magnus Lundqvist, Aman Mebrahtu, Johan Brengdahl, Ulf Gehrmann, Elisabeth Bäck, Douglas Ross-Thriepland, Ida Isaksson, Björn Magnusson, Kris F. Sachsenmeier, Hanna Tegel, Sophia Hober, Mathias Uhlén, Lorenz M. Mayr, Rick Davies, Johan Rockberg, Lovisa Holmberg Schiavone
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Regulatory T cells (Tregs) are the key cells regulating peripheral autoreactive T lymphocytes. Tregs exert their function by suppressing effector T cells. Tregs have been shown to play essential roles in the control of a variety of physiolog
Externí odkaz:
https://doaj.org/article/3192eee1ef58427faaa5eafd5d5b98ec
Autor:
Magdalena Malm, Rasool Saghaleyni, Magnus Lundqvist, Marco Giudici, Veronique Chotteau, Ray Field, Paul G. Varley, Diane Hatton, Luigi Grassi, Thomas Svensson, Jens Nielsen, Johan Rockberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/9b25893b02334dbda85e6f0d5d50fee7
Autor:
Mona Moradi Barzadd, Magnus Lundqvist, Claire Harris, Magdalena Malm, Anna-Luisa Volk, Niklas Thalén, Veronique Chotteau, Luigi Grassi, Andrew Smith, Marina Leal Abadi, Giulia Lambiase, Suzanne Gibson, Diane Hatton, Johan Rockberg
Publikováno v:
New Biotechnology. 68:68-76
Aggregation of therapeutic bispecific antibodies negatively affects the yield, shelf-life, efficacy and safety of these products. Pairs of stable Chinese hamster ovary (CHO) cell lines produced two difficult-to-express bispecific antibodies with diff
Autor:
Helen O. Masson, Chih-Chung Kuo, Magdalena Malm, Magnus Lundqvist, Åsa Sievertsson, Anna Berling, Hanna Tegel, Sophia Hober, Mathias Uhlén, Luigi Grassi, Diane Hatton, Johan Rockberg, Nathan E. Lewis
Mammalian cells are critical hosts for the production of most therapeutic proteins and many proteins for biomedical research. While cell line engineering and bioprocess optimization have yielded high protein titers of some recombinant proteins, many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82f4ecdf5b0e71e7f84289a2ca503249
https://doi.org/10.1101/2022.12.12.520152
https://doi.org/10.1101/2022.12.12.520152
Autor:
Malin Jönsson, Julia Scheffel, Emma Larsson, Marit Möller, Gabriella Rossi, Magnus Lundqvist, Johan Rockberg, Mathias Uhlén, Hanna Tegel, Sara Kanje, Sophia Hober
Publikováno v:
New biotechnology. 72
Protein activity regulated by interactions with metal ions can be utilized for many different purposes, including biological therapies and bioprocessing, among others. Calcium ions are known to interact with the frequently occurring EF-hand motif, wh
Autor:
Tomas Ottosson, Rick Davies, Elisabeth Bäck, Lovisa Holmberg Schiavone, Mathias Uhlén, Johan Rockberg, Kris Sachsenmeier, Hanna Tegel, Mei Ding, Johan Brengdahl, Ulf Gehrmann, Lorenz M. Mayr, Björn Magnusson, Sophia Hober, Ida Isaksson, Rajneesh Malhotra, Aman Mebrahtu, Magnus Lundqvist, Douglas Ross-Thriepland
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Regulatory T cells (Tregs) are the key cells regulating peripheral autoreactive T lymphocytes. Tregs exert their function by suppressing effector T cells. Tregs have been shown to play essential roles in the control of a variety of physiological and
Autor:
Emma von Witting, Sarah Lindbo, Magnus Lundqvist, Marit Möller, Andreas Wisniewski, Sara Kanje, Johan Rockberg, Hanna Tegel, Mikael Åstrand, Mathias Uhlén, Sophia Hober
Publikováno v:
Molecular Pharmaceutics. 19:3451-3451
Autor:
Thomas Svensson, Ray Field, Veronique Chotteau, Jens Nielsen, Luigi Grassi, Diane Hatton, Rasool Saghaleyni, Marco Giudici, Paul Varley, Johan Rockberg, Magnus Lundqvist, Magdalena Malm
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Scientific Reports
Scientific Reports
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Mathias Uhlén, Malin Westin, Andreas Hober, LanLan Xu, Björn Forsström, Bjørn G. Voldborg, Faranak Bidad, Siri Ekblad, Delaram Afshari, Lovisa Holmberg Schiavone, Hanna Tegel, Kalle von Feilitzen, Johan Rockberg, Jenny Ottosson Takanen, Fredrik Edfors, Sophia Hober, Anne-Sophie Svensson, Melanie Dannemeyer, Henric Enstedt, Magnus Lundqvist, Sinead Knight, Sven Göpel, Martin Zwahlen, Mona Moradi, Anna Berling, Rick Davies, Anna-Luisa Volk, Åsa Sivertsson, Lorenz M. Mayr, Sara Kanje
Publikováno v:
Tegel, H, Dannemeyer, M, Kanje, S, Sivertsson, Å, Berling, A, Svensson, A S, Hober, A, Enstedt, H, Volk, A L, Lundqvist, M, Moradi, M, Afshari, D, Ekblad, S, Xu, L L, Westin, M, Bidad, F, Schiavone, L H, Davies, R, Mayr, L M, Knight, S, Göpel, S O, Voldborg, B G, Edfors, F, Forsström, B, von Feilitzen, K, Zwahlen, M, Rockberg, J, Takanen, J O, Uhlén, M & Hober, S 2020, ' High throughput generation of a resource of the human secretome in mammalian cells ', New Biotechnology, vol. 58, pp. 45-54 . https://doi.org/10.1016/j.nbt.2020.05.002
The proteins secreted by human tissues and blood cells, the secretome, are important both for the basic understanding of human biology and for identification of potential targets for future diagnosis and therapy. Here, a high-throughput mammalian cel