Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Magnus Köping-Höggård"'
Publikováno v:
International Journal of Pharmaceutics. 382:205-214
Ionically crosslinked nanoparticles based on high and low molecular weight chitosans (CS) were formulated with plasmid DNA or dsDNA oligomers using the ionic gelation technique with pentasodium tripolyphospate (TPP) as crosslinking agent. The resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2200005f35d904b138420a2960445f78
https://doi.org/10.1016/j.ijpharm.2009.07.028
https://doi.org/10.1016/j.ijpharm.2009.07.028
Autor:
Noemi Csaba, Ramon Novoa-Carballal, Ricardo Riguera, María J. Alonso, Magnus Köping-Höggård, Eduardo Fernandez-Megia
Publikováno v:
Journal of Biomedical Nanotechnology. 5:162-171
The purpose of this work was to develop a new type of nanoparticles made of PEG-grafted chi-tosans (CS-g-PEG) using tripolyphosphate (TPP) as a polyanionic crosslinker and to investigate the potential of these nanostructures as gene carriers. The for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80c982481b53da0f379bac1fdc332738
https://doi.org/10.1166/jbn.2009.1017
https://doi.org/10.1166/jbn.2009.1017
Autor:
Per Artursson, Magnus Köping-Höggård, Bjørn E. Christensen, Kjell M. Vårum, Mohamed M. Issa, Kristoffer Tømmeraas, Sabina P. Strand
Publikováno v:
Journal of Controlled Release. 115:103-112
The aim of this study was to improve the gene delivery efficacy of chitosan oligomer polyplexes by introducing a trisaccharide branch that targets cell-surface lectins. For this purpose, chitosan oligomers were substituted by a trisaccharide with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36746fa81ef4445e3c692d80b715ca72
https://doi.org/10.1016/j.jconrel.2006.06.029
https://doi.org/10.1016/j.jconrel.2006.06.029
Publikováno v:
Pharmaceutical Research. 23:475-482
This study compared gene expression profiles in mouse lungs after administration of the cationic polymers polyethyleneimine (PEI) or chitosan alone or formulated with a luciferase reporter plasmid (PEI–pLuc, chitosan–pLuc). The polymers and formu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bdfc463b71f6c8af6c7c9ec5b507c6e
https://doi.org/10.1007/s11095-006-9563-7
https://doi.org/10.1007/s11095-006-9563-7
Publikováno v:
Expert Review of Vaccines. 4:185-196
At present, there is considerable excitement within the nanotechnology field with regard to the potential use of nanosystems as carriers for mucosal vaccine delivery. Indeed, many of the vaccines available, including protein antigens and DNA vaccines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2517d533e826736a625450c43a90d339
https://doi.org/10.1586/14760584.4.2.185
https://doi.org/10.1586/14760584.4.2.185
Publikováno v:
Drug Discovery Today: Technologies. 2:1-6
Recent human and animal studies have indicated that chitosan-based delivery systems are promising alternatives to conventional formulation approaches for the mucosal delivery of biotechnology drugs, such as proteins and genes. Here, we briefly analyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b86b70eb0355aacb95ca2118a209c8c
https://doi.org/10.1016/j.ddtec.2005.05.008
https://doi.org/10.1016/j.ddtec.2005.05.008
Autor:
Kristoffer Tømmeraas, Bjørn E. Christensen, Kjell M. Vårum, Magnus Köping-Höggård, Olav Smidsrød, Per Artursson
Publikováno v:
Carbohydrate Research. 337:2455-2462
The trimer 2-acetamido-2-deoxy-D-glucopyranosyl-beta-(1--4)-2-acetamido-2-deoxy-D-glucopyranosyl-beta-(1--4)-2,5-anhydro-D-mannofuranose (A-A-M) was reductively N-alkylated onto a fully de-N-acetylated chitosan (F(A)0.001, DP(n)=25) to obtain branche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037d22c4807be59bfd3ca40b8e035d87
https://doi.org/10.1016/s0008-6215(02)00334-8
https://doi.org/10.1016/s0008-6215(02)00334-8
Publikováno v:
The Journal of Gene Medicine. 5:130-141
Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62797e3bccbbbaecaa68e19f26ef0318
https://doi.org/10.1002/jgm.327
https://doi.org/10.1002/jgm.327
Autor:
Noemi, Csaba, Magnus, Köping-Höggård, Eduardo, Fernandez-Megia, Ramon, Novoa-Carballal, Ricardo, Riguera, Maria Jose, Alonso
Publikováno v:
Journal of biomedical nanotechnology. 5(2)
The purpose of this work was to develop a new type of nanoparticles made of PEG-grafted chi-tosans (CS-g-PEG) using tripolyphosphate (TPP) as a polyanionic crosslinker and to investigate the potential of these nanostructures as gene carriers. The for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b816bcf623bb7ffb5e1188bb1db7dd46
https://pubmed.ncbi.nlm.nih.gov/20055094
https://pubmed.ncbi.nlm.nih.gov/20055094
Autor:
Kjell M. Vårum, Ann Tronde, Per Artursson, Tamara Köhler, Mohamed M. Issa, Magnus Köping-Höggård
Publikováno v:
The journal of gene medicine. 7(9)
In this thesis, chitosan, a biocompatible polysaccharide that has been approved as a food additive was selected as a platform for the development of safe, efficient non-viral gene delivery systems to mammalian cells. Previously, chitosan-based gene f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c54b36722eafb5f59b5be286e074737
https://pubmed.ncbi.nlm.nih.gov/15895386
https://pubmed.ncbi.nlm.nih.gov/15895386