Cefuroxime concentrations in the anterior and posterior column of the lumbar spine – an experimental porcine study

Autor: Anne Schmedes, Mats Bue, Maiken Stilling, Alexander Emil Kaspersen, Kristian Høy, Pelle Hanberg, Magnus A. Hvistendahl

Publikováno v: Hvistendahl, M A, Bue, M, Hanberg, P, Kaspersen, A E, Schmedes, A V, Stilling, M & Høy, K 2022, ' Cefuroxime concentrations in the anterior and posterior column of the lumbar spine-an experimental porcine study ', The Spine Journal, vol. 22, no. 9, pp. 1434-1441 . https://doi.org/10.1016/j.spinee.2022.05.010

BACKGROUND CONTEXT: Surgical site infection following spine surgery is associated with increased morbidity and mortality. Perioperative antibiotic prophylaxis is a key factor in lowering the risk of acquiring an infection. Previous studies have asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51daea74eb9288586304b77e5ebc9410
https://doi.org/10.1016/j.spinee.2022.05.010

Subtherapeutic levels of cefuroxime inside a cannulated pedicle screw used in spine surgery: results from a porcine microdialysis study

Autor: Mats Bue, Maiken Stilling, Alexander Emil Kaspersen, Kristian Høy, Pelle Hanberg, Magnus A. Hvistendahl

Publikováno v: Hvistendahl, M A, Hanberg, P, Stilling, M, Kaspersen, A E, Høy, K & Bue, M 2022, ' Subtherapeutic levels of cefuroxime inside a cannulated pedicle screw used in spine surgery : results from a porcine microdialysis study ', Acta Orthopaedica, vol. 93, pp. 874-879 . https://doi.org/10.2340/17453674.2022.5276

BACKGROUND AND PURPOSE: Minimally invasive spine surgery has continuously evolved for specific surgical procedures and patient populations to lower morbidity and the risk of postoperative bacterial infection. Perioperative antibiotic prophylaxis is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa914f5970741d49555d85c5421b30fd
https://pubmed.ncbi.nlm.nih.gov/36445157

Evaluation of Benzylpenicillin as an Internal Standard for Measurement of Piperacillin Bone Concentrations Via Microdialysis

Autor: Kjeld Søballe, Magnus A. Hvistendahl, Martin Bruun Knudsen, Louise L. Pontoppidan, Pelle Hanberg, Mats Bue, Maiken Stilling

Publikováno v: Knudsen, M, Bue, M, Pontoppidan, L L, Hvistendahl, M A, Søballe, K, Stilling, M & Hanberg, P 2021, ' Evaluation of Benzylpenicillin as an Internal Standard for Measurement of Piperacillin Bone Concentrations Via Microdialysis ', Journal of Pharmaceutical Sciences, vol. 110, no. 10, pp. 3500-3506 . https://doi.org/10.1016/j.xphs.2021.06.008

Microdialysis is a pharmacokinetic tool that can be advantageous when obtaining tissues’ pharmacokinetic information. Since absolute extracellular tissue concentrations are needed in pharmacokinetic studies, calibrating the microdialysis system is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cc05175aa53994f937a409ae12088e
https://pure.au.dk/portal/da/publications/evaluation-of-benzylpenicillin-as-an-internal-standard-for-measurement-of-piperacillin-bone-concentrations-via-microdialysis(34561258-6cec-4b25-8408-b9f7a332bad0).html

[Untreated os odontoideum may cause tetraplegia]

Autor: Magnus A, Hvistendahl, Kristian, Høy

Publikováno v: Ugeskrift for laeger. 182(8)

This review summarises the present, limited, knowledge of os odontoideum (OO). The prevalence is unknown, and the aetiology is widely debated, though irrelevant to management of the disease. Surgery of symptomatic patients is advocated, as there is m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b56f26b18afcd517c9c404ced3d29656
https://pubmed.ncbi.nlm.nih.gov/32138818

Evaluation of single-dose cefuroxime concentrations in the spinal cord, cerebrospinal fluid, and epidural space in relation to lumbar spine surgery: An experimental porcine study

Autor: Alexander Emil Kaspersen, Pelle Hanberg, Magnus A. Hvistendahl, Mats Bue, Anne Vibeke Schmedes, Kristian Høy, Maiken Stilling

Publikováno v: Brain and Spine. 2:101083

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2811d84336abf733ea47566763fc601
https://doi.org/10.1016/j.bas.2022.101083