Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Magnus A. G. Hoffmann"'
Autor:
Zhi Yang, Kim-Marie A. Dam, Michael D. Bridges, Magnus A. G. Hoffmann, Andrew T. DeLaitsch, Harry B. Gristick, Amelia Escolano, Rajeev Gautam, Malcolm A. Martin, Michel C. Nussenzweig, Wayne L. Hubbell, Pamela J. Bjorkman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Neutralizing antibodies (bNAbs) against HIV-1 are exclusively directed against the viral envelope protein (Env) and mainly target Env in a closed, prefusion state. Here, Yang et al. structurally characterize two heterologously-neutralizing CD4-bindin
Externí odkaz:
https://doaj.org/article/a3f529a3512548c399bdcaadfab62202
Autor:
Harry B. Gristick, Harald Hartweger, Maximilian Loewe, Jelle van Schooten, Victor Ramos, Thiago Y. Oliveira, Yoshiaki Nishimura, Nicholas S. Koranda, Abigail Wall, Kai-Hui Yao, Daniel Poston, Anna Gazumyan, Marie Wiatr, Marcel Horning, Jennifer R. Keeffe, Magnus A. G. Hoffmann, Zhi Yang, Morgan E. Abernathy, Kim-Marie A. Dam, Han Gao, Priyanthi N. P. Gnanapragasam, Leesa M. Kakutani, Ana Jimena Pavlovitch-Bedzyk, Michael S. Seaman, Mark Howarth, Andrew T. McGuire, Leonidas Stamatatos, Malcolm A. Martin, Anthony P. West, Michel C. Nussenzweig, Pamela J. Bjorkman
Passive transfer of broadly neutralizing anti–HIV-1 antibodies (bNAbs) protects against infection, and therefore, eliciting bNAbs by vaccination is a major goal of HIV-1 vaccine efforts. bNAbs that target the CD4 binding site (CD4bs) on HIV-1 Env a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdfea6435d8275600e0a5a354868641
Autor:
Magnus A. G. Hoffmann, Zhi Yang, Kathryn E. Huey-Tubman, Alexander A. Cohen, Priyanthi N. P. Gnanapragasam, Leesa M. Nakatomi, Kaya N. Storm, Woohyun J. Moon, Paulo J.C. Lin, Pamela J. Bjorkman
Publikováno v:
bioRxiv : the preprint server for biology.
SummaryPrime-boost regimens for COVID-19 vaccines elicit poor antibody responses against Omicron-based variants and employ frequent boosters to maintain antibody levels. We present a natural infection-mimicking technology that combines features of mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3fbcb2b746a369b45251681cbe09fa
https://pubmed.ncbi.nlm.nih.gov/36597535
https://pubmed.ncbi.nlm.nih.gov/36597535
Autor:
Zhi, Yang, Kim-Marie A, Dam, Michael D, Bridges, Magnus A G, Hoffmann, Andrew T, DeLaitsch, Harry B, Gristick, Amelia, Escolano, Rajeev, Gautam, Malcolm A, Martin, Michel C, Nussenzweig, Wayne L, Hubbell, Pamela J, Bjorkman
Publikováno v:
Nature communications. 13(1)
Broadly-neutralizing antibodies (bNAbs) against HIV-1 Env can protect from infection. We characterize Ab1303 and Ab1573, heterologously-neutralizing CD4-binding site (CD4bs) antibodies, isolated from sequentially-immunized macaques. Ab1303/Ab1573 bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83a470073d9f0024e6db1b68a65f9eec
https://pubmed.ncbi.nlm.nih.gov/35136084
https://pubmed.ncbi.nlm.nih.gov/35136084