Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Magnus Ölander"'
Autor:
Niklas Handin, Di Yuan, Magnus Ölander, Christine Wegler, Cecilia Karlsson, Rasmus Jansson-Löfmark, Jøran Hjelmesæth, Anders Åsberg, Volker M. Lauschke, Per Artursson
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4361-4369 (2023)
Human liver tissue is composed of heterogeneous mixtures of different cell types and their cellular stoichiometry can provide information on hepatic physiology and disease progression. Deconvolution algorithms for the identification of cell types and
Externí odkaz:
https://doaj.org/article/398158ee84d44ea5b316e13587231791
Autor:
Magnus Ölander, Barbara S Sixt
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010669 (2022)
Externí odkaz:
https://doaj.org/article/9b1d719ac11b42d1b4cf053c7230f5c7
Autor:
Niklas Handin, Evgeniya Mickols, Magnus Ölander, Jakob Rudfeldt, Kristin Blom, Frida Nyberg, Wojciech Senkowski, Jozef Urdzik, Varun Maturi, Mårten Fryknäs, Per Artursson
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103235- (2021)
Summary: Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of
Externí odkaz:
https://doaj.org/article/6809c7fc5e7b425199479cb1e3e85b46
Autor:
Inken Flörkemeier, Tamara N. Steinhauer, Nina Hedemann, Magnus Ölander, Per Artursson, Bernd Clement, Dirk O. Bauerschlag
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Ovarian cancer (OvCa) constitutes a rare and highly aggressive malignancy and is one of the most lethal of all gynaecologic neoplasms. Due to chemotherapy resistance and treatment limitations because of side effects, OvCa is still not suf
Externí odkaz:
https://doaj.org/article/8b89334405764c299bc1e0e335c0f7dc
Autor:
Magnus, Ölander, Per, Artursson
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2543
We describe a simple protocol for quantification of apoptosis by counting subcellular debris particles in bright-field microscopy images of cell culture media samples. The only necessary equipment is a bright-field microscope (fitted with a digital c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1f4181f73fd83448bfcb73646a76eb3
https://pubmed.ncbi.nlm.nih.gov/36087256
https://pubmed.ncbi.nlm.nih.gov/36087256
Autor:
Bernd Clement, Per Artursson, Dirk Bauerschlag, Magnus Ölander, Tamara N. Steinhauer, Nina Hedemann, Inken Flörkemeier
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology
Background: Ovarian cancer (OvCa) constitutes a rare and highly aggressive malignancy and is one of the most lethal of all gynaecologic neoplasms. Due to chemotherapy resistance and treatment limitations because of side effects, OvCa is still not suf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9cace114206af7cc44e391575cec9c
https://doi.org/10.21203/rs.3.rs-743550/v1
https://doi.org/10.21203/rs.3.rs-743550/v1
Autor:
André Mateus, Anna Vildhede, Jozef Urdzik, Niklas Handin, Inken Flörkemeier, Per Artursson, Andrea Treyer, Jenny M. Pedersen, Christine Wegler, Edward L. LeCluyse, Magnus Ölander
Human hepatocytes show marked differences in cell size, gene expression, and function throughout the liver lobules, an arrangement termed liver zonation. However, it is not clear if these zonal size differences, and the associated phenotypic differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723ce6f18f99bb33ef3269c81c76dd21
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382404
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382404
Autor:
Kristin Blom, Evgeniya Mickols, Varun Maturi, Frida Nyberg, Magnus Ölander, Mårten Fryknäs, Per Artursson, Niklas Handin, Wojciech Senkowski, Jozef Urdzik, Jakob Rudfeldt
Publikováno v:
iScience
iScience, Vol 24, Iss 11, Pp 103235-(2021)
Handin, N, Mickols, E, Olander, M, Rudfeldt, J, Blom, K, Nyberg, F, Senkowski, W, Urdzik, J, Maturi, V, Fryknas, M & Artursson, P 2021, ' Conditions for maintenance of hepatocyte differentiation and function in 3D cultures ', iScience, vol. 24 . https://doi.org/10.1016/j.isci.2021.103235
iScience, Vol 24, Iss 11, Pp 103235-(2021)
Handin, N, Mickols, E, Olander, M, Rudfeldt, J, Blom, K, Nyberg, F, Senkowski, W, Urdzik, J, Maturi, V, Fryknas, M & Artursson, P 2021, ' Conditions for maintenance of hepatocyte differentiation and function in 3D cultures ', iScience, vol. 24 . https://doi.org/10.1016/j.isci.2021.103235
Summary Spheroid cultures of primary human hepatocytes (PHH) are used in studies of hepatic drug metabolism and toxicity. The cultures are maintained under different conditions, with possible confounding results. We performed an in-depth analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77703915293bd04de1f3fd4148e5ab7
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-463531
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-463531
Publikováno v:
LIVER INTERNATIONAL
Background & Aims The human liver functions through a complex interplay between parenchymal and non-parenchymal cells. Mass spectrometry-based proteomic analysis of intact tissue has provided an in-depth view of the human liver proteome. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c96ed1e1b1667c8edcf8717233b2759
https://hdl.handle.net/21.11116/0000-0006-56CE-221.11116/0000-0006-56D0-E
https://hdl.handle.net/21.11116/0000-0006-56CE-221.11116/0000-0006-56D0-E
Autor:
Patrik Lundquist, Magnus Ölander, Tommy B. Andersson, Anders Åsberg, Christine Wegler, Per Artursson, Katharina Zettl, Jøran Hjelmesæth, Jacek R. Wiśniewski
Publikováno v:
NAR Genomics and Bioinformatics
Genes and proteins show variable expression patterns throughout the human body. However, it is not clear whether relative differences in mRNA concentrations are retained on the protein level. Furthermore, inter-individual protein concentration variab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0345f9bd075b40628e676d6695176a9
https://doi.org/10.1093/nargab/lqz010
https://doi.org/10.1093/nargab/lqz010