Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Magnus, Kaffarnik"'
Autor:
Rawan Alraish, Sebastian G. Wicha, Otto R. Frey, Anka C. Roehr, Johann Pratschke, Martin Stockmann, Tilo Wuensch, Magnus Kaffarnik
Publikováno v:
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Background In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated predominantly by the live
Externí odkaz:
https://doaj.org/article/ed651372be7f461492268892b1da5ad3
Publikováno v:
Antibiotics, Vol 11, Iss 4, p 479 (2022)
This study investigated tigecycline exposure in critically ill patients from a population pharmacokinetic perspective to support rational dosing in intensive care unit (ICU) patients with acute and chronic liver impairment. A clinical dataset of 39 p
Externí odkaz:
https://doaj.org/article/b30d8e86a21245a98da966b2038b08bc
Autor:
Sebastian G. Wicha, Rawan Alraish, Magnus Kaffarnik, Anka C Roehr, Martin Stockmann, Otto R Frey, Tilo Wuensch, Johann Pratschke
Publikováno v:
Technology and Health Care. 30:309-321
BACKGROUND: Critically ill patients commonly suffer from infections that require antimicrobial therapy. In previous studies, liver dysfunction was shown to have an essential impact on the dose selection in these patients. This pilot study aims to ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c2d8046b068e59802593a19d04d0d2
https://doi.org/10.3233/thc-191847
https://doi.org/10.3233/thc-191847
Autor:
Ruza Arsenic, Maximilian Jara, Martin Stockmann, Bruno Valentin Sinn, J Quint, Jonas Wizenty, Niklas Heucke, Magnus Kaffarnik, Tilo Wuensch, Johann Pratschke
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 316:G608-G614
Dynamic liver function assessment by the [13C]methacetin maximal liver function capacity (LiMAx) test reflects the overall hepatic cytochrome P-450 (CYP) 1A2 activity. One proven strategy for preoperative risk assessment in liver surgery includes the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79aed8e6013bd847ee7d9f63409c6567
https://doi.org/10.1152/ajpgi.00335.2018
https://doi.org/10.1152/ajpgi.00335.2018
Autor:
Tilo Wuensch, Felix Aigner, Magnus Kaffarnik, Verena Mueller, J Quint, Jonas Wizenty, Johann Pratschke, Anne Mueller, Matthias Biebl, Barbara Kern, Martin Stockmann
Publikováno v:
Clinical Nutrition ESPEN. 30:131-137
Summary Background & aims Prolonged preoperative fasting periods lead to catabolic states and decelerate recovery after surgery. Valid plasma markers reflecting the patients‘ metabolic state may improve tailored nutrition support before surgery. Wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6506ebd8ab85b64d93853f7c4a0489
https://doi.org/10.1016/j.clnesp.2019.01.004
https://doi.org/10.1016/j.clnesp.2019.01.004
Autor:
Rawan, Alraish, Sebastian G, Wicha, Otto R, Frey, Anka C, Roehr, Johann, Pratschke, Martin, Stockmann, Tilo, Wuensch, Magnus, Kaffarnik
Publikováno v:
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-9 (2020)
Annals of Intensive Care
Annals of Intensive Care
Background In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated predominantly by the liver. Critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5878a2188bd13a9b19d57e7ecefcdb44
https://doi.org/10.17169/refubium-28043
https://doi.org/10.17169/refubium-28043
Publikováno v:
Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie. 143:241-249
ZusammenfassungClostridium-difficile-Infektionen (CDI) gehören zu den häufigsten Ursachen einer Diarrhö bei hospitalisierten internistischen und chirurgischen Patienten. Das klinische Bild reicht von milden Durchfällen bis hin zu einer pseudomemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::543227df5665052c76fd011e840bd322
https://doi.org/10.1055/s-0043-119894
https://doi.org/10.1055/s-0043-119894
Autor:
Tilo Wuensch, Martin Stockmann, Magnus Kaffarnik, Rawan Alraish, Anka C Roehr, Johann Pratschke, Otto R Frey, Sebastian G. Wicha
Publikováno v:
International Journal of Antimicrobial Agents. 50:557-563
Patients in the intensive care unit frequently require antibiotic treatment. Liver impairment poses substantial challenges for dose selection in these patients. The aim of the present pilot study was to assess the novel maximal liver function capacit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa9d3b434b9f322743057ed11cd6caa
https://doi.org/10.1016/j.ijantimicag.2017.06.023
https://doi.org/10.1016/j.ijantimicag.2017.06.023
Autor:
Gabriel Stoeger, Christian Grieser, Martin Stockmann, Magnus Kaffarnik, Johann Pratschke, Julia Liebich
Publikováno v:
World Journal of Surgery. 42:557-566
Major abdominal surgery may lead to a systemic inflammatory response (SIRS) with a risk of organ failure. One possible trigger for a postoperative hepatic dysfunction is an altered hepatic blood flow during SIRS, resulting in a decreased oxygen deliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f1926d4cafaa34cf54db6001d31a5c
https://doi.org/10.1007/s00268-017-4170-9
https://doi.org/10.1007/s00268-017-4170-9
Publikováno v:
Der Chirurg. 89:40-49
Only a few antibiotics are available for treatment of infections with multidrug resistant gram-negative bacteria (MRGN). The management of patients with MRGN colonization or infection is therefore of great importance with respect to postoperative mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2b17ef12fdca1622aab408c5856bfd
https://doi.org/10.1007/s00104-017-0476-2
https://doi.org/10.1007/s00104-017-0476-2