Zobrazeno 1 - 10 of 54 pro vyhledávání: '"Magis Mandapathil"'
1
Akademický článek
CD31 and VEGF are prognostic biomarkers in early-stage, but not in late-stage, laryngeal squamous cell carcinoma
Autor: Anke Schlüter, Patrick Weller, Oliver Kanaan, Ivonne Nel, Lukas Heusgen, Benedikt Höing, Pia Haßkamp, Sebastian Zander, Magis Mandapathil, Nina Dominas, Judith Arnolds, Boris A. Stuck, Stephan Lang, Agnes Bankfalvi, Sven Brandau
Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Patients suffering from squamous cell carcinoma of the larynx (LSCC) with lymphatic metastasis have a relatively poor prognosis and often require radical therapeutic management. The mechanisms which drive metastasis to the lymph n
Externí odkaz: https://doaj.org/article/c714c62e803c4494b6d19fb9807a7376
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2
Akademický článek
Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg).
Autor: Marta Szajnik, Malgorzata Czystowska, Miroslaw J Szczepanski, Magis Mandapathil, Theresa L Whiteside
Publikováno v: PLoS ONE, Vol 5, Iss 7, p e11469 (2010)
Tumor-derived microvesicles (TMV) or exosomes are present in body fluids of patients with cancer and might be involved in tumor progression. The frequency and suppressor functions of peripheral blood CD4(+)CD25(high)FOXP3(+) Treg are higher in patien
Externí odkaz: https://doaj.org/article/ccd91c329ef24ed1b65a2d0452f71158
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3
Akademický článek
Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin.
Autor: Laura Strauss, Malgorzata Czystowska, Marta Szajnik, Magis Mandapathil, Theresa L Whiteside
Publikováno v: PLoS ONE, Vol 4, Iss 6, p e5994 (2009)
The immunosuppressive drug rapamycin (RAPA) promotes the expansion of CD4(+) CD25(high)Foxp3(+) regulatory T cells via mechanisms that remain unknown. Here, we studied expansion, IL-2R-gamma chain signaling, survival pathways and resistance to apopto
Externí odkaz: https://doaj.org/article/99bfa2a3785542a399676810338295ac
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5
Supplemental Figure 1 from Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells
Autor: Samir N. Khleif, Theresa L. Whiteside, Jay A. Berzofsky, Mikayel Mkrtichyan, Nadya Tarasova, Andrea Carnie, Jiahua Qian, Willie Wilson, Saudat Adamson-Fadeyi, Rasha Abu Eid, Magis Mandapathil, Stephanie Zdanov
Supplemental Figure 1: (A) mRNA level of Kras in wild-type Kras tumor cells (Colo320) overexpressing mutant KrasG12V plasmid (Kras Pd) is significantly higher than cells with a mock plasmid. (B) Representative dot plots showing that the percentage of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b512d69b214900c943d0b915f56ce859
https://doi.org/10.1158/2326-6066.22538867.v1
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7
Data from Increased Ectonucleotidase Expression and Activity in Regulatory T Cells of Patients with Head and Neck Cancer
Autor: Theresa L. Whiteside, Jonas T. Johnson, Stephan Lang, Elieser Gorelik, Edwin K. Jackson, Diana E. Lenzner, Jin Ren, Marta Szajnik, Miroslaw J. Szczepanski, Magis Mandapathil
Purpose: Regulatory T cell (Treg) frequency and activity are increased in cancer patients and play a major role in tumor escape. Although disease progression is favored by the presence of Treg, mechanisms used by Treg to suppress antitumor immunity a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c59e273a7fa636459ee5e3b53a8015
https://doi.org/10.1158/1078-0432.c.6516814
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8
Significance and management of incidentally diagnosed metastatic papillary thyroid carcinoma in cervical lymph nodes in neck dissection specimens
Autor: Paul Lennon, Snehal G. Patel, Ian Ganly, Magis Mandapathil, Jatin P. Shah
Publikováno v: Head & Neck. 41:3783-3787
Background The management of patients with incidentally discovered metastatic thyroid cancer in cervical lymph nodes in neck dissection specimens for other pathologies is unclear. Methods Retrospective review of neck dissection specimens for nonthyro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfd67dc2a0c778a9f0b7d438e95c85d
https://doi.org/10.1002/hed.25905
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10
Breast cancer cell-derived adenosine enhances generation and suppressor function of human adaptive regulatory t cells
Autor: Magis Mandapathil, Miroslaw J. Szczepanski, Edwin K. Jackson, Theresa L. Whiteside, Stephan Lang
Publikováno v: Journal of Personalized Medicine, Vol 11, Iss 754, p 754 (2021)
Journal of Personalized Medicine
Volume 11
Issue 8
Introduction: Adaptive regulatory T cells (Tr1) are induced in the periphery by environmental stimuli. CD73 expression and adenosine (ADO) production by tumor cells may influence Tr1 generation and their immunosuppressive activity. Material and Metho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3604b0e3a3b8d35d16ff53d8388fbbe8
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85112486918
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