Výsledky vyhledávání - "Magie M. Kapojos"

Akademický článek

Screening for Small Molecule Inhibitors of BMP-Induced Osteoblastic Differentiation from Indonesian Marine Invertebrates

Autor: Hiroyuki Yamazaki, Satoshi Ohte, Henki Rotinsulu, Defny S. Wewengkang, Deiske A. Sumilat, Delfly B. Abdjul, Wilmar Maarisit, Magie M. Kapojos, Michio Namikoshi, Takenobu Katagiri, Hiroshi Tomoda, Ryuji Uchida

Publikováno v: Marine Drugs, Vol 18, Iss 12, p 606 (2020)

Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder with heterotopic ossification (HO) in soft tissues. The abnormal activation of bone morphogenetic protein (BMP) signaling by a mutant activin receptor-like kinase-2 (ALK2) lead

Externí odkaz: https://doaj.org/article/f9e7be7129464f43aa42b3f4c9b8323a

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Screening of Indonesian Edible Plants for Bioactive Constituents and a New Protein Tyrosine Phosphatase 1B Inhibitory Acylbenzene Derivative from Leaves of Indonesian Syzygium polyanthum

Autor: Hiroyuki Yamazaki, Magie M. Kapojos, Ryuji Uchida, Delfly B. Abdjul, Akiho Yagi

Publikováno v: Chemical and Pharmaceutical Bulletin. 68:903-906

Bioassay screening using Indonesian plants, such as traditional foods (vegetables, spices, and tea) and folk medicinal herbs, identified eight protein tyrosine phosphatase (PTP) 1B inhibitory and two antibacterial plants. The leaves of Syzygium polya

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e176df1b9b51c2474589e8fb7f4a4c
https://doi.org/10.1248/cpb.c20-00457

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Screening for Small Molecule Inhibitors of BMP-Induced Osteoblastic Differentiation from Indonesian Marine Invertebrates

Autor: Delfly B. Abdjul, Satoshi Ohte, Magie M. Kapojos, Takenobu Katagiri, Defny S. Wewengkang, Henki Rotinsulu, Hiroyuki Yamazaki, Deiske A. Sumilat, Ryuji Uchida, Wilmar Maarisit, Hiroshi Tomoda, Michio Namikoshi

Publikováno v: Marine Drugs
Marine Drugs, Vol 18, Iss 606, p 606 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5039691b7962e43c9289381f03600f8e
http://europepmc.org/articles/PMC7761252

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Inhibitory effects of sesquiterpene lactones from the Indonesian marine sponge Lamellodysidea cf. herbacea on bone morphogenetic protein-induced osteoblastic differentiation

Autor: Ryuji Uchida, Henki Rotinsulu, Fumiaki Hayashi, Magie M. Kapojos, Wilmar Maarisit, Ohgi Takahashi, Deiske A. Sumilat, Defny S. Wewengkang, Hiroyuki Yamazaki, Delfly B. Abdjul, Satoshi Ohte, Hiroshi Tomoda, Huiping Zhang, Takenobu Katagiri, Michio Namikoshi

Publikováno v: Bioorganicmedicinal chemistry letters. 35

A new unique sesquiterpene lactone, bicyclolamellolactone A (1), was isolated together with two known monocyclofarnesol-type sesquiterpenes, lamellolactones A (2) and B (3), from the Indonesian marine sponge Lamellodysidea sp. (cf. L. herbacea). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec848939dbcc7007a6dc089243fcc72
https://pubmed.ncbi.nlm.nih.gov/33422607

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Absolute Structures of Wedelolide Derivatives and Structure–Activity Relationships of Protein Tyrosine Phosphatase 1B Inhibitory ent-Kaurene Diterpenes from Aerial Parts of Wedelia spp. Collected in Indonesia and Japan

Autor: Delfly B. Abdjul, Ohgi Takahashi, Michio Namikoshi, Ryota Kirikoshi, Henki Rotinsulu, Defny S. Wewengkang, Hiroyuki Yamazaki, Wilmar Maarisit, Fitje Losung, Deiske A. Sumilat, Ayako Tomizawa, Syu-ichi Kanno, Magie M. Kapojos

Publikováno v: Chemical and Pharmaceutical Bulletin. 66:682-687

Two sesquiterpene lactones with the (9R)-eudesman-9,12-olide framework, wedelolides I and J, have been isolated together with five eudesmanolide sesquiterpenes and twelve ent-kaurene diterpenes from the aerial parts of Indonesian Wedelia prostrata. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66fe23d19bf630546baef68ad7da5f4a
https://doi.org/10.1248/cpb.c18-00117

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Protein tyrosine phosphatase 1B inhibitory polybromobiphenyl ethers and monocyclofarnesol-type sesquiterpenes from the Indonesian marine sponge Lamellodysidea cf. herbacea

Autor: Kazuyo Ukai, Ohgi Takahashi, Delfly B. Abdjul, Henki Rotinsulu, Defny S. Wewengkang, Michio Namikoshi, Ryota Kirikoshi, Magie M. Kapojos, Deiske A. Sumilat, Hiroyuki Yamazaki

Publikováno v: Phytochemistry Letters. 24:10-14

Three known polybromobiphenyl ether derivatives, 2-(2′,4′-dibromophenoxy)-3,5-dibromophenol (1), 2-(2′,4′-dibromophenoxy)-4,6-dibromophenol (2), and 2-(2′-dibromophenoxy)-3,4,5,6-tetrabromophenol (3), were identified as PTP1B inhibitors fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca0b7857e48f301630eb7ea6d5786e4e
https://doi.org/10.1016/j.phytol.2017.11.016

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Anti-mycobacterial alkaloids, cyclic 3-alkyl pyridinium dimers, from the Indonesian marine sponge Haliclona sp

Autor: Kazuyo Ukai, Magie M. Kapojos, Henki Rotinsulu, Wilmar Maarisit, Hajime Kato, Delfly B. Abdjul, Defny S. Wewengkang, Michio Namikoshi, Hiroyuki Yamazaki, Deiske A. Sumilat

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 27:3503-3506

Three new dimeric 3-alkyl pyridinium alkaloids, named haliclocyclamines A-C (1-3), were isolated together with five known congeners, cyclostellettamines A (4), B (5), C (6), E (7), and F (8), from the Indonesian marine sponge Haliclona sp. The struct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56df05e0bbc5880551b0732f50acc87f
https://doi.org/10.1016/j.bmcl.2017.05.067

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An anti-mycobacterial bisfunctionalized sphingolipid and new bromopyrrole alkaloid from the Indonesian marine sponge Agelas sp

Autor: Defny S. Wewengkang, Deiske A. Sumilat, Syu-ichi Kanno, Kazuyo Ukai, Michio Namikoshi, Henki Rotinsulu, Ayako Tomizawa, Hiroyuki Yamazaki, Magie M. Kapojos, Delfly B. Abdjul

Publikováno v: Journal of Natural Medicines. 71:531-536

In the course of our studies on anti-mycobacterial substances from marine organisms, the known dimeric sphingolipid, leucettamol A (1), was isolated as an active component, together with the new bromopyrrole alkaloid, 5-bromophakelline (2), and twelv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf318e0f1a20c2b58e822bd16aeb89c3
https://doi.org/10.1007/s11418-017-1085-6

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Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp

Autor: Ryuji Uchida, Deiske A. Sumilat, Delfly B. Abdjul, Henki Rotinsulu, Defny S. Wewengkang, Hiroyuki Yamazaki, Taichi Ohshiro, Magie M. Kapojos, Hiroshi Tomoda, Michio Namikoshi

Publikováno v: Bioorganicmedicinal chemistry letters. 28(10)

Callyspongiamides A (1) and B (2), two new sterol O-acyltransferase (SOAT) inhibitors, were isolated from the Indonesian marine sponge Callyspongia sp. together with a known congener, dysamide A (3). The structures of 1 and 2 were elucidated to be po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7573aba9fa8486e4864f229261a12e4c
https://pubmed.ncbi.nlm.nih.gov/29631961

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Oleanane triterpenes with protein tyrosine phosphatase 1B inhibitory activity from aerial parts of Lantana camara collected in Indonesia and Japan

Autor: Kazuyo Ukai, Michio Namikoshi, Henki Rotinsulu, Wilmar Maarisit, Hiroyuki Yamazaki, Magie M. Kapojos, Delfly B. Abdjul, Deiske A. Sumilat, Fitje Losung, Defny S. Wewengkang

Publikováno v: Phytochemistry. 144

During the search for new protein tyrosine phosphatase (PTP) 1B inhibitors, EtOH extracts from the aerial parts of Lantana camara L. (lantana) collected at Manado (Indonesia) and two subtropical islands in Japan (Ishigaki and Iriomote Islands, Okinaw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0b317991dcd3884e169d799c70ac2a
https://pubmed.ncbi.nlm.nih.gov/28917090

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