Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maggie Zi-ying Chow"'
Autor:
Andy On-Tik Wong, Gabriel Wong, Michael Shen, Maggie Zi-Ying Chow, Wan Wai Tse, Bimal Gurung, Suet Yee Mak, Deborah K. Lieu, Kevin D. Costa, Camie W. Chan, Alain Martelli, Joseph F. Nabhan, Ronald A. Li
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background Friedreich’s ataxia (FRDA) is an autosomal recessive disease caused by a non-coding mutation in the first intron of the frataxin (FXN) gene that suppresses its expression. Compensatory hypertrophic cardiomyopathy, dilated cardio
Externí odkaz:
https://doaj.org/article/c3b3d53d2d4149ee959b9aaaf70281c0
Autor:
Andy On-Tik Wong, Nicodemus Wong, Lin Geng, Maggie Zi-ying Chow, Eugene K. Lee, Hongkai Wu, Michelle Khine, Chi-Wing Kong, Kevin D. Costa, Wendy Keung, Yiu-Fai Cheung, Ronald A. Li
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Although biomimetic stimuli, such as microgroove-induced alignment (μ), triiodothyronine (T3) induction, and electrical conditioning (EC), have been reported to promote maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), a s
Externí odkaz:
https://doaj.org/article/6067fb36fc424dfabd152826270cc5fd
Autor:
Dongbo Ding, Qing Li, Maggie Zi-Ying Chow, Kui Ming Chan, Junhong Han, Michael S.Y. Huen, Yuchen Zhang, Toyotaka Ishibashi, Du Yang, Tze Zhen Evangeline Kang, Yi Ching Esther Wan, Lina Zhu, Xin Wang, Jiaxian Liu, Zongli Zheng, Ajay Goel, Tsz Chui Sophia Leung, Chengmin Qian, Jitian Zhang, Xulun Sun
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-4 (2020)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Autor:
Chenyu Lu, Chunwei Xu, Shifeng Lian, William Chi Shing Cho, Zongli Zheng, Maggie Zi-Ying Chow, Zhengbo Song, Firaol Tamiru Kebede, Wah Cheuk, Yanqiu Gao, Hoi Yee Keung, Wenxian Wang, Silvia Y.L. Mak, Mengsu Yang
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 17(2)
Introduction Gene fusion variants in ALK-rearranged NSCLC may predict patient outcomes, but previous results have been inconclusive. Fusion isoforms coexisting in the same tumor may affect the efficacy of targeted therapy, but they have not been inve
Autor:
Chunwei Xu, Mengsu Yang, Siyu Bao, Hongxiang Wang, Wah Cheuk, Zhengbo Song, Zhenyu Gong, Baifeng Zhang, Chenyu Lu, Yiping Zhang, Wenxian Wang, Zongli Zheng, Maggie Zi-Ying Chow, Hoi Yee Keung, Chloe Yufan Bao, Hoi Yee Chu, Juxiang Chen, William Chi Shing Cho
Gene fusions are common drivers and therapeutic targets in cancers, but clinical-grade bioinformatics callers are lacking. Here we introduce a novel method SplitFusion, which is fast by leveraging BWA-MEM split alignments, can detect cryptic splice s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f6cb14e3301dd4086aeb4ba06bfc15f
https://doi.org/10.21203/rs.3.rs-39138/v1
https://doi.org/10.21203/rs.3.rs-39138/v1
Autor:
Becky K. C. Chan, Koon Ho Wong, Yufan Bao, Jieran Sun, Yuk Kei Wan, Chaya T. L. Yuen, Jien Vei Khaw, Maggie Zi-Ying Chow, Sophia Shek Wa Zhong, Suet Yi Leung, Cindy S.W. Tong, Gigi C. G. Choi, Xinran Li, H.Y. Edwin Chan, Peng Zhou, Lydia W.T. Cheung, Silvia Y.L. Mak, Alan S.L. Wong, Zongli Zheng, Kaeling Tan
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108020-(2020)
Summary: We present a CRISPR-based multi-gene knockout screening system and toolkits for extensible assembly of barcoded high-order combinatorial guide RNA libraries en masse. We apply this system for systematically identifying not only pairwise but
Autor:
Angie Man-Yee Shum, Andy On‑Tik Wong, Camie W. Chan, Chi-Wing Kong, Lin Geng, Ronald A. Li, Hui Che, Maggie Zi-Ying Chow, Ka-Long Yau, Chenzi Zhang, Wendy Keung
Publikováno v:
Toxicology Letters. 294:61-72
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are emerging tools for applications such as drug discovery and screening for pro-arrhythmogenicity and cardiotoxicity as leading causes for drug attrition. Understanding the electrophysiol
Autor:
Maggie Zi-Ying Chow, Lihuan Ren, Chi-Wing Kong, Wendy Keung, Andy O.-T. Wong, Christopher S. Chen, Roger J. Hajjar, Lin Geng, Kevin D. Costa, Jean-Sébastien Hulot, Ronald A. Li, Stephanie N. Sadrian
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.7502. ⟨10.1038/s41598-019-42953-w⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, 2019, 9 (1), pp.7502. ⟨10.1038/s41598-019-42953-w⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.7502. ⟨10.1038/s41598-019-42953-w⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, 2019, 9 (1), pp.7502. ⟨10.1038/s41598-019-42953-w⟩
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have the ability of differentiating into functional cardiomyocytes (CMs) for cell replacement therapy, tissue engineering, drug discovery and toxicity screening. From a sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e562ae86a4785f8ba03eebb7aa4aa79f
https://hal.sorbonne-universite.fr/hal-02136611
https://hal.sorbonne-universite.fr/hal-02136611
Autor:
Zhihui Weng, Jiaozi He, Howard C.H. Chow, Harvey Y.S. Chan, Maggie Zi Ying Chow, Ioannis Karakikes, Chong Fai Mok, Andrew L. Miller, Sarah E. Webb, Ronald A. Li, Anskar Y.H. Leung, Lin Geng, Lihuan Ren, Camie W. Chan, Roger J. Hajjar, Chi-Wing Kong, Wendy Keung
Publikováno v:
Stem Cells and Development. 23:1704-1716
Self-renewable human pluripotent stem cells (hPSCs) serve as a potential unlimited ex vivo source of human cardiomyocytes (CMs) for cell-based disease modeling and therapies. Although recent advances in directed differentiation protocols have enabled
Autor:
Anant Chopra, Christopher S. Chen, Wendy Keung, Roger J. Hajjar, Lihuan Ren, Bin Yan, Camie W.Y. Chan, Sen Li, Ronald A. Li, Gaopeng Chen, Maggie Zi-Ying Chow, Ioannis Karakikes, Chi Wing Kong, Kevin D. Costa
Publikováno v:
Circulation. Arrhythmia and electrophysiology. 8(1)
Background— Human (h) embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) serve as a potential unlimited ex vivo source of cardiomyocytes (CMs). However, a well-accepted roadblock has been their immature phenotype. hESC/iPSC-deri