Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Maggie L. Lesch"'
Autor:
Taylor P. Uccello, Maggie L. Lesch, Sarah A. Kintzel, Lauren B. Gradzewicz, Lillia Lamrous, Shawn P. Murphy, Fergal J. Fleming, Bradley N. Mills, Joseph D. Murphy, Angela Hughson, Gary Hannon, Jesse Garrett-Larsen, Haoming Qiu, Michael G. Drage, Jian Ye, Nicholas W. Gavras, David C. Keeley, Tanzy M. T. Love, Elizabeth A. Repasky, Edith M. Lord, David C. Linehan, Scott A. Gerber
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-12 (2023)
Abstract Rectal cancer ranks as the second leading cause of cancer-related deaths. Neoadjuvant therapy for rectal cancer patients often results in individuals that respond well to therapy and those that respond poorly, requiring life-altering excisio
Externí odkaz:
https://doaj.org/article/e9b3abc8040b4f838d19d476c4b23ebc
Autor:
Jian Ye, Brian A Belt, David C Linehan, Tara G Vrooman, Carl J Johnston, Edith M Lord, Scott A Gerber, Nicholas W Gavras, David C Keeley, Angela L Hughson, Gary Hannon, Maggie L Lesch, Jim Eyles
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background Stereotactic body radiotherapy (SBRT) induces immunogenic cell death, leading to subsequent antitumor immune response that is in part counterbalanced by activation of immune evasive processes, for example, upregulation of programmed cell d
Externí odkaz:
https://doaj.org/article/df0812d98765426e92ae92d48cf997b7
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Hematopoiesis takes place in the bone marrow and is supported by a complex cellular and molecular network in the bone marrow microenvironment. Commonly used models of the human bone marrow microenvironment include murine models and two-dimensional an
Externí odkaz:
https://doaj.org/article/3fd0f8822d7c4deb8f1832dd678e652f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7359 (2023)
Ionizing radiation (IR) is used to treat 50% of cancers. While the cytotoxic effects related to DNA damage with IR have been known since the early 20th century, the role of the immune system in the treatment response is still yet to be fully determin
Externí odkaz:
https://doaj.org/article/44749f25760846fda09be8245883323f
Autor:
Taylor P. Uccello, Maggie L. Lesch, Nicholas A. Ullman, Sarah A. Kintzel, Lauren B. Gradzewicz, Trishna Velagaleti, Fergal J. Fleming, Bradley N. Mills, Joseph D. Murphy, Jesse Garrett-Larsen, Haoming Qiu, Michael G. Drage, Jian Ye, Nicholas W. Gavras, Carl J. Johnston, Tanzy M.T. Love, Elizabeth A. Repasky, David C. Linehan, Edith M. Lord, Scott A. Gerber
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:733-745
Many solid tumors present with perineural invasion (PNI), and innervation correlates with worsened prognosis. The effects that commonly administered therapies such as radiation therapy (RT) have on PNI status remain unknown. We investigated the contr
Publikováno v:
Blood. 140:8620-8621
Autor:
Danielle S. W. Benoit, Maggie L Lesch, Benjamin J. Frisch, Celia Soto, Laura M. Calvi, Marian A. Ackun-Farmmer, Daniel Byun, Lila Yang
Publikováno v:
FASEB J
Leukemias are challenging diseases to treat due, in part, to interactions between leukemia cells and the bone marrow microenvironment (BMME) that contribute significantly to disease progression. Studies have shown that leukemic cells secrete C-chemok
Autor:
Hannon, Gary1,2,3 (AUTHOR) gary_hannon@urmc.rochester.edu, Lesch, Maggie L.1,2,3,4 (AUTHOR) maggie_lesch@urmc.rochester.edu, Gerber, Scott A.1,2,3,4 (AUTHOR) scott_gerber@urmc.rochester.edu
Publikováno v:
International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 8, p7359. 18p.
Autor:
Uccello, Taylor P., Lesch, Maggie L., Kintzel, Sarah A., Gradzewicz, Lauren B., Lamrous, Lillia, Murphy, Shawn P., Fleming, Fergal J., Mills, Bradley N., Murphy, Joseph D., Hughson, Angela, Hannon, Gary, Garrett-Larsen, Jesse, Qiu, Haoming, Drage, Michael G., Ye, Jian, Gavras, Nicholas W., Keeley, David C., Love, Tanzy M. T., Repasky, Elizabeth A., Lord, Edith M.
Publikováno v:
Cell Death & Disease; Jul2023, Vol. 14 Issue 7, p1-12, 12p
Publikováno v:
Drug Week; 8/18/2023, p1100-1100, 1p