Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Maggie L. Kalev‐Zylinska"'
Autor:
Christopher Puli'uvea, Tracey Immanuel, Taryn N. Green, Peter Tsai, Peter R. Shepherd, Maggie L. Kalev-Zylinska
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
ABSTRACTObjectives: This study aimed to compile bioinformatic and experimental information for JAK2 missense variants previously reported in myeloproliferative neoplasms (MPN) and determine if germline JAK2-I724T, recently found to be common in New Z
Externí odkaz:
https://doaj.org/article/ce5b4c33076141b4ba8b6008985068fb
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Peripheral circadian clocks control cell proliferation and survival, but little is known about their role and regulation in megakaryocytic cells. N-methyl-D-aspartate receptor (NMDAR) regulates the central clock in the brain. The purpose of this stud
Externí odkaz:
https://doaj.org/article/afeb4773c4bc4f6b93c64575c2ed336c
Autor:
Jixia Li, Maggie L. Kalev‐Zylinska
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia (AML) in which leukemic blasts have megakaryocytic features. AMKL makes up 4%–15% of newly diagnosed pediatric AML, typically affecting young children (less than 2 y
Externí odkaz:
https://doaj.org/article/88994926e86548418db4349b2b0a13b6
Autor:
Maggie L. Kalev-Zylinska, Marie-Christine Morel-Kopp, Christopher M. Ward, James I. Hearn, Justin R. Hamilton, Anna Y. Bogdanova
Publikováno v:
Platelets, Vol 32, Iss 8, Pp 998-1008 (2021)
Ionotropic glutamate receptors include α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR), kainate receptors (KAR), and N-methyl-D-aspartate receptors (NMDAR). All function as cation channels; AMPAR and KAR are more permeable to
Externí odkaz:
https://doaj.org/article/a829641581a743f3aaf4651569c06150
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Intracellular calcium signaling regulates diverse physiological and pathological processes. In solid tumors, changes to calcium channels and effectors via mutations or changes in expression affect all cancer hallmarks. Such changes often disrupt tran
Externí odkaz:
https://doaj.org/article/db30d79531af4374b2f3a147e31793bc
Autor:
Jixia Li, Maggie L. Kalev-Zylinska
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Myeloid leukemia associated with Down syndrome (ML-DS) has a unique molecular landscape that differs from other subtypes of acute myeloid leukemia. ML-DS is often preceded by a myeloproliferative neoplastic condition called transient abnormal myelopo
Externí odkaz:
https://doaj.org/article/66352ea91848443b8e9ad3c4b7674b31
Publikováno v:
Current Oncology, Vol 28, Iss 2, Pp 1544-1557 (2021)
Background: There is a paucity of data on ethnic disparities in patients with the classical Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs): polycythaemia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF)
Externí odkaz:
https://doaj.org/article/dfe9b776eed0423b92b2f0cf344e2c08
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The N-methyl-D-aspartate receptor (NMDAR) provides a pathway for glutamate-mediated inter-cellular communication, best known for its role in the brain but with multiple examples of functionality in non-neuronal cells. Data previously published by oth
Externí odkaz:
https://doaj.org/article/7d34b9a11340419d8ad88d6f4050947b
Autor:
Taryn N. Green, Justin R. Hamilton, Marie-Christine Morel-Kopp, Zhaohua Zheng, Ting-Yu T. Chen, James I. Hearn, Peng P. Sun, Jack U. Flanagan, Deborah Young, P. Alan Barber, Matthew J. During, Christopher M. Ward, Maggie L. Kalev-Zylinska
Publikováno v:
Platelets, Vol 28, Iss 8, Pp 799-811 (2017)
GluN1 is a mandatory component of N-methyl-D-aspartate receptors (NMDARs) best known for their roles in the brain, but with increasing evidence for relevance in peripheral tissues, including platelets. Certain anti-GluN1 antibodies reduce brain infar
Externí odkaz:
https://doaj.org/article/777a1eb7851b450190f5c33b151b9622
Autor:
Young Eun Park, Rushi Penumarthy, Paul P. Sun, Caroline Y. Kang, Marie-Christine Morel-Kopp, Jonathan Downing, Taryn N. Green, Tracey Immanuel, Christopher M. Ward, Deborah Young, Matthew J. During, P. Alan Barber, Maggie L. Kalev-Zylinska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8398 (2020)
Ischaemic brain damage induces autoimmune responses, including the production of autoantibodies with potential neuroprotective effects. Platelets share unexplained similarities with neurons, and the formation of anti-platelet antibodies has been docu
Externí odkaz:
https://doaj.org/article/d6fe794e0c7648f7bb8dab6be13af2c5