Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maggie H Chasse"'
Autor:
Maggie H Chasse, Benjamin K Johnson, Elissa A Boguslawski, Katie M Sorensen, Jessica E Rosien, Min H Kang, C Patrick Reynolds, Lyong Heo, Zachary B Madaj, Ian Beddows, Gabrielle E Foxa, Susan M Kitchen‐Goosen, Bart O Williams, Timothy J Triche, Patrick J Grohar
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 2, Pp 1-21 (2020)
Abstract Rhabdoid tumor (RT) is a pediatric cancer characterized by the inactivation of SMARCB1, a subunit of the SWI/SNF chromatin remodeling complex. Although this deletion is the known oncogenic driver, there are limited effective therapeutic opti
Externí odkaz:
https://doaj.org/article/18bf94a3ea2d4e32b5861a62e60c62a8
Autor:
Patrick J. Grohar, Megan J. Bowman, Zachary B. Madaj, Anderson S. Peck, Stephen L. Lessnick, Cenny Taslim, Scott B. Rothbart, Susan M. Kitchen-Goosen, Jenna M. Gedminas, Katie M. Sorensen, Elissa A. Boguslawski, Maggie H. Chasse, Matt L. Harlow
Supplementary Data S1A-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b32c5e473ddd63dd6ea4eea3d986ed
https://doi.org/10.1158/1078-0432.22469283
https://doi.org/10.1158/1078-0432.22469283
Autor:
Patrick J. Grohar, Megan J. Bowman, Zachary B. Madaj, Anderson S. Peck, Stephen L. Lessnick, Cenny Taslim, Scott B. Rothbart, Susan M. Kitchen-Goosen, Jenna M. Gedminas, Katie M. Sorensen, Elissa A. Boguslawski, Maggie H. Chasse, Matt L. Harlow
Purpose:The successful clinical translation of compounds that target specific oncogenic transcription factors will require an understanding of the mechanism of target suppression to optimize the dose and schedule of administration. We have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312d8d91c38ac89cf2c6e4ee313809dd
https://doi.org/10.1158/1078-0432.c.6527196
https://doi.org/10.1158/1078-0432.c.6527196
Autor:
Elissa Boguslawski, Cenny Taslim, Patrick J. Grohar, Jenna M. Gedminas, Katie M. Sorensen, Zachary Madaj, Maggie H. Chasse, Matt Harlow, Anderson Peck, Susan M. Kitchen-Goosen, Scott B. Rothbart, Megan J. Bowman, Stephen L. Lessnick
Publikováno v:
Clin Cancer Res
Purpose:The successful clinical translation of compounds that target specific oncogenic transcription factors will require an understanding of the mechanism of target suppression to optimize the dose and schedule of administration. We have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b33b818c947ba11e02fce46abbb51b
https://doi.org/10.1158/1078-0432.ccr-18-3511
https://doi.org/10.1158/1078-0432.ccr-18-3511
Autor:
Katie M. Sorensen, Min H. Kang, Bart O. Williams, Lyong Heo, Patrick J. Grohar, Timothy J. Triche, Jessica E Rosien, C. Patrick Reynolds, Maggie H. Chasse, Zachary Madaj, Gabrielle E. Foxa, Benjamin K. Johnson, Ian Beddows, Elissa Boguslawski, Susan M. Kitchen-Goosen
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
Rhabdoid tumor (RT) is a pediatric cancer characterized by the inactivation of SMARCB1, a subunit of the SWI/SNF chromatin remodeling complex. Although this deletion is the known oncogenic driver, there are limited effective therapeutic options for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce177656448726f6f48983b706f49feb
https://pubmed.ncbi.nlm.nih.gov/33332735
https://pubmed.ncbi.nlm.nih.gov/33332735
Autor:
Patrick J. Grohar, Susan M. Kitchen-Goosen, Jenna M. Gedminas, Maggie H. Chasse, Mitchell McBrairty, Ian Beddows
Publikováno v:
Oncogenesis
Oncogenesis, Vol 9, Iss 4, Pp 1-8 (2020)
Oncogenesis, Vol 9, Iss 4, Pp 1-8 (2020)
Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive soft-tissue malignancy with a poor overall survival and no effective therapeutic options. The tumor is believed to be dependent on the continued activity of the oncogenic EWS-WT1 tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e8aa0d96f89100de69e25114968dcb
http://europepmc.org/articles/PMC7188842
http://europepmc.org/articles/PMC7188842
Autor:
Katie M. Sorensen, Maggie H. Chasse, Bart O. Williams, Susan M. Kitchen-Goosen, Patrick J. Grohar, Zachary Madaj, Elissa Boguslawski, Ian Beddows, Kristin J. Rybski, Gabrielle E. Foxa, Timothy J. Triche, Benjamin K. Johnson
Publikováno v:
Cancer Research. 80:A75-A75
The text of this abstract has not been printed at the request of the authors due to intellectual property matters. Citation Format: Maggie H. Chasse, Benjamin K. Johnson, Elissa A. Boguslawski, Katie M. Sorensen, Ian Beddows, Zachary Madaj, Gabrielle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::965e4c4de2237b42609fa0f190f31530
https://doi.org/10.1158/1538-7445.pedca19-a75
https://doi.org/10.1158/1538-7445.pedca19-a75
Autor:
Patrick J. Grohar, Katie M. Sorensen, Ian Beddows, Susan M. Kitchen-Goosen, Elissa Boguslawski, Maggie H. Chasse, Kristin J. Rybski, Zachary Madaj
Publikováno v:
Cancer Research. 79:2883-2883
BACKGROUND: Rhabdoid tumor (RT) is an aggressive pediatric malignancy defined by the genetic deletion of SMARCB1 (BAF47/SNF5/INI1), a subunit of the SWI/SNF chromatin remodeling complex. SMARCB1 loss redistributes the SWI/SNF complex to favor a proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09090cc2bae8a205d2f8dde81ab171de
https://doi.org/10.1158/1538-7445.am2019-2883
https://doi.org/10.1158/1538-7445.am2019-2883
Autor:
Elissa Boguslawski, Katie M. Sorensen, Susan M. Goosen, Patrick J. Grohar, Maggie H. Chasse, Courtney E. Wernette
Publikováno v:
Cancer Research. 78:A32-A32
Background: Rhabdoid tumor (RT) is a rare pediatric cancer characterized by the genetic silencing of SMARCB1 (SNF5/INI1), a critical subunit of the SWI/SNF chromatin remodeling complex. SMARCB1 deletion drives oncogenic transformation through redistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8779a4f68d70e5b32db490e9367e48e
https://doi.org/10.1158/1538-7445.pedca17-a32
https://doi.org/10.1158/1538-7445.pedca17-a32
Autor:
Patrick J. Grohar, Susan M. Kitchen-Goosen, Elissa Boguslawski, Maggie H. Chasse, Courtney E. Wernette
Publikováno v:
Cancer Research. 78:4634-4634
BACKGROUND: Rhabdoid tumor (RT) is an aggressive pediatric malignancy defined by the genetic deletion of BAF47 (SMARCB1/SNF5/INI1), a subunit of the BAF chromatin remodeling complex. Loss of BAF47 leads to BAF complex redistribution and overexpressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9feaea7d020a6c1217626e926d7c6e08
https://doi.org/10.1158/1538-7445.am2018-4634
https://doi.org/10.1158/1538-7445.am2018-4634