Mitochondrial Morphology, Function and Homeostasis Are Impaired by Expression of an N-terminal Calpain Cleavage Fragment of Ataxin-3.

Autor: Harmuth T; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Centre for Rare Diseases, Tübingen, Germany.; Graduate School of Cellular Neuroscience, University of Tübingen, Tübingen, Germany., Prell-Schicker C; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Weber JJ; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Centre for Rare Diseases, Tübingen, Germany., Gellerich F; Department of Neurology, University Hospital Magdeburg, Magdeburg, Germany., Funke C; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Drießen S; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Magg JCD; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Centre for Rare Diseases, Tübingen, Germany., Krebiehl G; Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Wolburg H; Institute of Pathology and Neuropathology, University of Tübingen, Tübingen, Germany., Hayer SN; German Center for Neurodegenerative Diseases, Tübingen, Germany.; Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany., Hauser S; German Center for Neurodegenerative Diseases, Tübingen, Germany., Krüger R; Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg., Schöls L; German Center for Neurodegenerative Diseases, Tübingen, Germany.; Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany., Riess O; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Centre for Rare Diseases, Tübingen, Germany., Hübener-Schmid J; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; Centre for Rare Diseases, Tübingen, Germany.

Publikováno v: Frontiers in molecular neuroscience [Front Mol Neurosci] 2018 Oct 10; Vol. 11, pp. 368. Date of Electronic Publication: 2018 Oct 10 (Print Publication: 2018).

Mutant Ataxin-3–Containing Aggregates (MATAGGs) in Spinocerebellar Ataxia Type 3: Dynamics of the Disorder.

Autor: Raj, Kritika, Akundi, Ravi Shankar

Publikováno v: Molecular Neurobiology; Jul2021, Vol. 58 Issue 7, p3095-3118, 24p