Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Magfur E. Alam"'
Autor:
Magfur E. Alam, Thomas R. Slaney, Peter M. Tessier, Sambit R. Kar, Tapan K. Das, Anthony Leone, Lina Wu, Gregory V. Barnett
Publikováno v:
Journal of Pharmaceutical Sciences. 109:656-669
Monoclonal antibodies are attractive therapeutic agents because of their impressive biological activities and favorable biophysical properties. Nevertheless, antibodies are susceptible to various types of chemical modifications, and the impact of suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c6fa5babbb0da9c5b4dbad6f8496b1
https://doi.org/10.1016/j.xphs.2019.10.051
https://doi.org/10.1016/j.xphs.2019.10.051
Autor:
Tapan K. Das, Gregory V. Barnett, Charles G. Starr, Thomas R. Slaney, Peter M. Tessier, Magfur E. Alam
Publikováno v:
Molecular pharmaceutics. 16(5)
Monoclonal antibodies must be both chemically and physically stable to be developed into safe and effective drugs. Although there has been considerable progress in separately understanding the molecular determinants of antibody chemical and physical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca914dadab981198da28d595f2cc2f2
https://pubmed.ncbi.nlm.nih.gov/30916563
https://pubmed.ncbi.nlm.nih.gov/30916563
Autor:
Rene Hoet, Lars Linden, Seth D. Ludwig, Christian Bender, Steven B. Geng, Peter M. Tessier, Magfur E. Alam
Publikováno v:
Molecular pharmaceutics. 15(1)
In vitro antibody discovery and/or affinity maturation are often performed using antibody fragments (Fabs), but most monovalent Fabs are reformatted as bivalent IgGs (monoclonal antibodies, mAbs) for therapeutic applications. One problem related to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5b61db0dba032f545890bb6c0d0d14
https://pubmed.ncbi.nlm.nih.gov/29154550
https://pubmed.ncbi.nlm.nih.gov/29154550