Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Magesh Muthu"'
Autor:
Jaganathan Venkatesh, Magesh Muthu, Indulekha Singaravelu, Vino T. Cheriyan, Sreeja C. Sekhar, Nuwan C. P. N. Acharige, Edi Levi, Hadeel Assad, Mary Kay H. Pflum, Arun K. Rishi
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
CARP-1, a perinuclear phospho-protein, regulates cell survival and apoptosis signaling induced by genotoxic drugs. However, kinase(s) phosphorylating CARP-1 and down-stream signal transduction events remain unclear. Here we find that CARP-1 Serine (S
Externí odkaz:
https://doaj.org/article/b16e0fa2d7b74d1285d89bd2f8c2e8b6
Autor:
Thejaswi Bhandary, Christine Kurian, Magesh Muthu, Asha Anand, Thirunavukarasou Anand, Kuppusamy Alagesan Paari
Publikováno v:
Journal of Pure and Applied Microbiology, Vol 17, Iss 1, Pp 35-50 (2023)
Probiotic bacteria are producers of secretory products such as bacteriocins and polysaccharides. Both homopolymeric and heteropolymeric exopolysaccharides (EPS) present on the surface of microorganisms have shown beneficial properties. While the fact
Externí odkaz:
https://doaj.org/article/a70a333cdce7463fa81210dcf6a8fcf2
Autor:
Shazia Jamal, Vino T Cheriyan, Magesh Muthu, Sara Munie, Edi Levi, Abdelkader E Ashour, Harvey I Pass, Anil Wali, Mandip Singh, Arun K Rishi
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89146 (2014)
Malignant pleural mesothelioma (MPM) is an asbestos-related thoracic malignancy that is characterized by late metastases, and resistance to therapeutic modalities. The toxic side-effects of MPM therapies often limit their clinical effectiveness, thus
Externí odkaz:
https://doaj.org/article/f40d635b267c4d139155c3e53e35e55b
Autor:
Magesh Muthu, Vino T Cheriyan, Sara Munie, Edi Levi, John Frank, Abdelkader E Ashour, Mandip Singh, Arun K Rishi
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102567 (2014)
Neuroblastomas (NBs) are a clinically heterogeneous group of extra cranial pediatric tumors. Patients with high-risk, metastatic NBs have a long-term survival rate of below 40%, and are often resistant to current therapeutic modalities. Due to toxic
Externí odkaz:
https://doaj.org/article/665b33b573f44330a603203ee012b541
Autor:
Vino T Cheriyan, Ying Wang, Magesh Muthu, Shazia Jamal, Di Chen, Huanjie Yang, Lisa A Polin, Adi L Tarca, Harvey I Pass, Q Ping Dou, Sunita Sharma, Anil Wali, Arun K Rishi
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93711 (2014)
Dithiocarbamate compound Disulfiram (DSF) that binds with copper and functions as an inhibitor of aldehyde dehydrogenase is a Food and Drug Administration approved agent for treatment of alcoholism. Copper complexed DSF (DSF-Cu) also possesses anti-t
Externí odkaz:
https://doaj.org/article/e8c60f27c3214726a5d924a7e3e81f78
Autor:
Abdelkader E Ashour, Shazia Jamal, Vino T Cheryan, Magesh Muthu, Khairy M A Zoheir, Ahmed M Alafeefy, Adel R Abd-Allah, Edi Levi, Adi L Tarca, Lisa A Polin, Arun K Rishi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66733 (2013)
Medulloblastomas (MBs) constitute an aggressive class of intracranial pediatric tumors. Current multimodality treatments for MBs include surgery, ionizing radiation, and chemotherapy. Toxic side effects of therapies coupled with high incidence of rec
Externí odkaz:
https://doaj.org/article/e497f474c46f4f8b89d52f4f5def5f99
Publikováno v:
Cancer Research. 83:3737-3737
CARP-1, a perinuclear phospho-protein, is a biphasic regulator of cell survival and apoptosis signaling. Genotoxic drugs induce apoptosis in part by elevating CARP-1 levels while also promote cell survival in part by activating NF-κB that involves C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05a5c24f8cd5639a0780db021b415f1d
https://doi.org/10.1158/1538-7445.am2023-3737
https://doi.org/10.1158/1538-7445.am2023-3737
Publikováno v:
Cancer Research. 83:3738-3738
CARP-1, a perinuclear phospho-protein, is a biphasic regulator of cell survival and apoptosis signaling induced by genotoxic drugs. We have previously found that apoptosis induced by genotoxic drugs involved elevated levels of CARP-1. Exposure to gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8815214523f68fa47e65ff7d2785a1
https://doi.org/10.1158/1538-7445.am2023-3738
https://doi.org/10.1158/1538-7445.am2023-3738
Autor:
Jaganathan Venkatesh, Arun K. Rishi, Lisa Polin, Sijana H. Dzinic, Edi Levi, James W. Gauld, Paul Meister, Vino T. Cheriyan, Magesh Muthu, Sreeja C. Sekhar
Publikováno v:
J Biol Chem
NF-κB is a pro-inflammatory transcription factor that critically regulates immune responses and other distinct cellular pathways. However, many NF-κB–mediated pathways for cell survival and apoptosis signaling in cancer remain to be elucidated. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec98a4a4c93e019dc2609688e052d79a
https://doi.org/10.1074/jbc.ra119.009898
https://doi.org/10.1074/jbc.ra119.009898
Autor:
Jonathan D. Gilthorpe, Ranjeet Kumar, Azharuddin Sajid Syed Khaja, Anders Nordström, Jenny L. Persson, Magesh Muthu
Publikováno v:
Cancers
Volume 11
Issue 12
Volume 11
Issue 12
Glutamate-ammonia ligase (GLUL) is important for acid-base homeostasis, ammonia detoxification, cell signaling, and proliferation. Here, we reported that GLUL ablation conferred resistance to several anticancer drugs in specific cancer cell lines whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac37e87dc75f2e466d72df4350002f9