Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maged K. G. Mekhael"'
Publikováno v:
Egyptian Pharmaceutical Journal.
Background and objective Corchorus (Family Tiliaceae) is a genus of annual herbs. Nearly 40 species are known to occur in nature and distributed in the tropics of both hemispheres. Because of the wide medicinal applications of compounds isolated ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f31285e31b6bd3c35abd34998d3d8a2
https://doi.org/10.4103/epj.epj_51_18
https://doi.org/10.4103/epj.epj_51_18
Publikováno v:
Helvetica Chimica Acta. 94:28-37
The successive treatment of the N,N-disubstituted 4-hydroxy-2-methylbutanamide 2a with lithium diisopropylamide (LDA) and diphenyl phosphorochloridate (DPPCl) led to the 1-methylcyclopropanecarboxamide 10 in good yield. This base-catalyzed cyclizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::578f11e14583ef3a53be62444a7a6e56
https://doi.org/10.1002/hlca.201000370
https://doi.org/10.1002/hlca.201000370
Autor:
Ahmed Abdelaziz, Peng Li, MingfengYu, Longjin Zhong, Khaled A.M. Abouzid, Shudong Wang, Atef G. Hanna, Maged K. G. Mekhael, Abdel Nasser B. Singab
Sulphonamides embrace a sublime class of drugs with various biological activities. Since the discovery of E7010 in 1992, several sulphonamides as anti-cancer drug candidates have been identified. Herein, a new series of 5-chloro- 2-methoxy-N-(4-sulph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86403ece5de5200269b81f60cdfe39ac
https://hdl.handle.net/11541.2/135691
https://hdl.handle.net/11541.2/135691
Publikováno v:
Helvetica Chimica Acta. 87:2385-2404
A novel general method for the synthesis of oxindoles, namely the 'azirine/oxindole ring enlargement via amidinium-intermediates' has been established: the reaction of 2H-azirin-3-amines 1 with BF3.OEt2 in THF solution at -78° leads to 1,3,3-trialky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64806781e04f3382b541e3f3c8461e2d
https://doi.org/10.1002/hlca.200490216
https://doi.org/10.1002/hlca.200490216
Autor:
Maged K. G. Mekhael, Heinz Heimgartner
Publikováno v:
Helvetica Chimica Acta. 86:2805-2813
(±)-Desoxynoreseroline (3), the basic ring structure of the pharmacologically active alkaloid physostigmine (1), was synthesized starting from 3-allyl-1,3-dimethyloxindole (9). The latter was prepared from the corresponding 2H-azirin-3-amine 6 by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9698de0251bf7d360c2dab4013a620f
https://doi.org/10.1002/hlca.200390231
https://doi.org/10.1002/hlca.200390231
Publikováno v:
ResearcherID
2,2,N-Trimethyl-N-phenyl-2H-azirin-3-amine (1a) was prepared by successive treatment of 2,N-dimethyl-N-phenylpropanamide (18) with phosgene, triethylamine, and sodium azide. Reaction of 1a in THF solution with boron trifluoride gave 2-amino-1,3,3-tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9547b370cb28988a650cc6a90a4378ca
https://doi.org/10.1515/znb-2002-0410
https://doi.org/10.1515/znb-2002-0410
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58a947a874c891d2854f6a25b964a3d
https://doi.org/10.1002/chin.199808230
https://doi.org/10.1002/chin.199808230
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47acc096d186f89607e37bbbec93d54
https://doi.org/10.1002/chin.200237123
https://doi.org/10.1002/chin.200237123
Publikováno v:
ChemInform. 40
The 2-monosubstituted 2H-azirin-3-amine (5c) was prepared conveniently by subsequent treatment of N-methyl-N-phenylpropanamide in THF with LDA, diphenyl phosphorochloridate (DPPCl) , and sodium azide in DMF. In the absence of nucleophiles, the reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aa1a12aaa284f4f4c824d8849e03546
https://doi.org/10.1002/chin.200909163
https://doi.org/10.1002/chin.200909163
A novel general method for the synthesis of oxindoles, namely the 'azirine/oxindole ring enlargement via amidinium-intermediates' has been established: the reaction of 2H-azirin-3-amines 1 with BF3.OEt2 in THF solution at -78° leads to 1,3,3-trialky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c808ada88792c0c1a8c7a9e05cb6406
https://www.zora.uzh.ch/id/eprint/79819/
https://www.zora.uzh.ch/id/eprint/79819/