Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Magdolna Kovacs"'
Autor:
Renzhi Cai, Tengjiao Cui, Jozsef L. Varga, Luca Szalontay, Marta Zarandi, Gabor Halmos, Andrew V. Schally, Xian Yang Zhang, Ferenc G. Rick, Petra Popovics, Wei Sha, Magdolna Kovacs, Norman L. Block, Miklós Jászberényi
Publikováno v:
Peptides. 89:60-70
The syntheses and biological evaluations of new GHRH analogs of Miami (MIA) series with greatly increased anticancer activity are described. In the design and synthesis of these analogs, the following previous substitutions were conserved: D-Arg2, Ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12287686b91c9f194313aa0ab0a1eef3
https://doi.org/10.1016/j.peptides.2017.01.009
https://doi.org/10.1016/j.peptides.2017.01.009
Autor:
Gabor Halmos, Erika Orbán, Gábor Mező, Ildikó Szabó, Magdolna Kovacs, Éva Sipos, Szilvia Bősze
Publikováno v:
Journal of Peptide Science. 21:426-435
Hormone based drug targeting is a promising tool for selective tumor therapy. In this study, synthesis and systematic comparative biological evaluation of novel drug containing analogs of gonadotropin-releasing hormone GnRH-I and GnRH-II is reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aace49d2d5d3da6cf8446a93fc0c5271
https://doi.org/10.1002/psc.2775
https://doi.org/10.1002/psc.2775
Autor:
Marta Zarandi, Joshua M. Hare, Rosemeire M. Kanashiro-Takeuchi, Renzhi Cai, Gabor Halmos, Wei Sha, Magdolna Kovacs, Petra Popovics, Ferenc G. Rick, Jinlin He, Tengjiao Cui, Luca Szalontay, Miklós Jászberényi, Norman L. Block, Andrew V. Schally
Publikováno v:
Peptides. 52:104-112
In view of the recent findings of stimulatory effects of GHRH analogs, JI-34, JI-36 and JI-38, on cardiomyocytes, pancreatic islets and wound healing, three series of new analogs of GHRH(1-29) have been synthesized and evaluated biologically in an en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e2024fc2ab3b4a1fc4823f97843448
https://doi.org/10.1016/j.peptides.2013.12.010
https://doi.org/10.1016/j.peptides.2013.12.010
Autor:
Filippo de Braud, Gianfranco Delle Fave, Norman L. Block, S.L. Miller, Marta Zarandi, Gabriele Capurso, Daniel J. Spergel, Luigi Dogliotti, Davide Campana, Aldo Scarpa, Vesna Starcevic, Luca Szalontay, Ralf Gilsbach, Mirjana Sumarac-Dumanovic, Mehrdad Nadji, Ignacio Camacho-Arroyo, Dragan Micic, D.W. Walker, Kristina Janjetovic, Druck Reinhardt Druck Basel, Paola Tomassetti, D.M. Yates, Mika Scheinin, J.J. Hirst, Maja Misirkic, Karla Hernández-Fonseca, Francesco Panzuto, Vladimir Trajkovic, Massimo Falconi, Andrew V. Schally, Giovanni Di Meglio, Ronald J. Benveniste, H.K. Palliser, Maria Pia Brizzi, Lutz Hein, Eriika Savontaus, Saku Ruohonen, E.M. Wallace, Ljubica Vucicevic, Magdolna Kovacs, Darko Stevanovic, Lourdes Massieu, Bailey A. Kermath, Suvi T. Ruohonen, Selene García de la Cadena, Xiao-Bing Zhang, Satz Mengensatzproduktion, Letizia Boninsegna, Nicola Fazio, Andrea C. Gore, Carolina Guzmán, Irving Vidaurre, Francesca Nori
Publikováno v:
Neuroendocrinology. 96:89-96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2013b8190459eb047a5c480e06709aa
https://doi.org/10.1159/000339309
https://doi.org/10.1159/000339309
Autor:
Magdolna Kovacs, Jozsef L. Varga, Florian Hohla, Marta Zarandi, Eva Pozsgai, Luca Szalontay, Andrew V. Schally, Ferenc G. Rick
Publikováno v:
Peptides. 31:1839-1846
GHRH receptor antagonists inhibit growth and metastasis of a large number of experimental tumors expressing the pituitary GHRH receptor (pGHRH-R) and its major splice variant SV1. In this study, using Western blot, we demonstrated that DBTRG-05 and U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2348eb52b1091deb5be198c2e90772c
https://doi.org/10.1016/j.peptides.2010.07.006
https://doi.org/10.1016/j.peptides.2010.07.006
Autor:
Istvan Teplan, Géza Tóth, Istvan Palyi, B. Vincze, Sándor Lovas, Magdolna Kovacs, I. Mezö, Richard F. Murphy, Judit Horvath
Publikováno v:
The Journal of Peptide Research. 52:384-389
In previous studies GnRH-III, a variant of the hypothalamic neurohormone GnRH, was isolated from the brain of the sea lamprey and structurally characterized. GnRH-III is a hypothalamic neurohormone in both female and male sea lampreys. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2803d8a0578f80d9944aaf446e8a4870
https://doi.org/10.1111/j.1399-3011.1998.tb00662.x
https://doi.org/10.1111/j.1399-3011.1998.tb00662.x
Autor:
Kate Groot, Marta Zarandi, Zoltan Kele, Magdolna Kovacs, Katalin Toth, Attila Nagy, Gabor Halmos, Andrew V. Schally
Publikováno v:
The Journal of Peptide Research. 51:134-141
Based on our previous results, in conjunction with various structural considerations, 19 new analogs of the GHRH antagonist [PhAc-Tyr1,D-Arg2,Phe(pCl)6,Abu15,Nle27,Agm29]++ +hGHRH(1-29) (MZ-5-156) were synthesized by the solid-phase method. These com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9604375a5dbef6ad2ea5c723d0f2d96
https://doi.org/10.1111/j.1399-3011.1998.tb00631.x
https://doi.org/10.1111/j.1399-3011.1998.tb00631.x
Publikováno v:
Current Medicinal Chemistry. 15:314-321
Potent antagonists of growth hormone-releasing hormone (GHRH) have been developed for the treatment of disorders caused by excessive GHRH or growth hormone (GH) production and for therapy of cancers. GHRH antagonists suppressed the release of GH and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e8011aa6b76e1ebc82352795995223
https://doi.org/10.2174/092986708783497355
https://doi.org/10.2174/092986708783497355
Autor:
Francine Herbert, Kate Groot, Judit E. Horvath, Andrew V. Schally, Magdolna Kovacs, Ana M. Bajo
Publikováno v:
Proceedings of the National Academy of Sciences. 99:15048-15053
The effects of depot formulations of the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl (25 μg/day) for 30 days or LHRH antagonist Cetrorelix pamoate (100 μg/day) for 30 days and daily injections of 100 μg of Decapeptyl for 10 day
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82444708dfdf906ead3dfb87f8c55616
https://doi.org/10.1073/pnas.232579499
https://doi.org/10.1073/pnas.232579499
Publikováno v:
Journal of Neuroendocrinology. 12:335-341
Previous studies have demonstrated that neonatal monosodium glutamate (MSG) treatment destroys growth hormone releasing-hormone (GHRH) neurones within the hypothalamic arcuate nucleus, decreases serum GH and insulin-like growth factor (IGF-I) concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccf359e57e6cbb8f2121206d2fc97d7d
https://doi.org/10.1046/j.1365-2826.2000.00458.x
https://doi.org/10.1046/j.1365-2826.2000.00458.x