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pro vyhledávání: '"Magdalini Papadaki"'
Autor:
Magdalini Papadaki
Publikováno v:
Frontiers in Medicine, Vol 4 (2017)
For the nascent field of advanced therapies, collaboration will be a game-changer, turning scientific progress that was once unimaginable into transformative medical practice. Despite promise for lifelong management and even cure of disease, skeptici
Externí odkaz:
https://doaj.org/article/63cded26bf75458db30e9ba2f10306fd
Autor:
Magdalini Papadaki
Publikováno v:
Regenerative Medicine. 11:229-234
For a field primed to deliver, can we envision the translational, policy & business paths for a long-term success? Methods and tools for ‘genetic engineering’ or ‘genetic modification’ have been used successfully for more than three decades i
Publikováno v:
Human Gene Therapy. 22:1293-1303
The promise of the RNA interference (RNAi) technology is equally dependent on the efficiency and stability of gene silencing. The aim of the present study was the development of foamy virus (FV) vectors for stable RNAi, utilizing two potent RNA polym
Autor:
Magdalini Papadaki, Evridiki Michali, Ioanna Savvidou, Nikos I. Anagnostopoulos, Dimitrios Gogos, Elena K. Siapati, Erasmia Rouka, George Vassilopoulos, Zoi Kozaou, Despina Kyriakou
Publikováno v:
British Journal of Haematology. 152:164-174
B-catenin is the central effector molecule of the canonical Wnt signalling pathway, which controls self-renewal of haematopoietic stem cells. Deregulation of this pathway occurs in various malignancies including myeloid leukaemias. The present study
Autor:
Sophia Hatziantoniou, P. Pantazis, Magdalini Papadaki, Costas Demetzos, Konstantinos Alevizopoulos, Kostas Dimas, C. Tsimplouli
Publikováno v:
Biomedicine & Pharmacotherapy. 60:127-133
Sclareol is a labdane-type diterpene that has demonstrated a significant cytotoxic activity against human leukemic cell lines. Here, we report the effect of sclareol against the human breast cancer cell lines MN1 and MDD2 derived from the parental ce
Autor:
Magdalini Papadaki, Gigi Hirsch
Publikováno v:
Science translational medicine. 5(200)
The complex pathology of consortium fatigue provides diagnostic data on how to improve collaboration in biomedical innovation.
Autor:
Steven D. Buckingham, Kazuhiko Matsuda, Magdalini Papadaki, Andrew K. Jones, David B. Sattelle, Benedict M. Sattelle, Maiko Yokota
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(13)
The molecular diversity of many gene products functioning in the nervous system is enhanced by alternative splicing and adenosine-to-inosine editing of pre-mRNA. Using RDL, aDrosophila melanogasterGABA-gated ion channel, we examined the functional im
Publikováno v:
Thalassemia Reports; Volume 3; Issue 11; Pages: e40
In the pathophysiology of beta-thalassemia, globin chain imbalance plays a central role in predicting red blood cell (RBC) life span and disease severity. Strategies to improve globin chain imbalance are therefore a legitimate target in the managemen
Publikováno v:
Human Gene Therapy; Oct2011, Vol. 22 Issue 10, p1293-1303, 11p