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pro vyhledávání: '"Magdalena Uzlíková"'
Autor:
Eva Nohynkova, Magdalena Uzlíková
Publikováno v:
Molecular and Biochemical Parasitology. 198:75-81
Metronidazole (MTZ) is used as the drug of choice to treat Giardia infections. It is believed that the prodrug is transformed intracellularly into toxic intermediates that interact with cellular components, leading to cell death. The present study ai
Publikováno v:
Molecular and biochemical parasitology. 211
The ends of linear chromosomes, telomeres, are most commonly maintained by the enzyme telomerase. Our study presents the characteristics of telomeres and telomerase from the single-celled parasitic eukaryote Giardia intestinalis. Using fluorescence i
Publikováno v:
Chromosoma. 124(1)
During mitotic prophase, chromosomes of the pathogenic unicellular eukaryote Giardia intestinalis condense in each of the cell’s two nuclei. In this study, Giardia chromosomes were investigated using light microscopy, high-resolution field emission
Publikováno v:
Scandinavian journal of infectious diseases. 44(9)
For many years Pneumocystis pneumonia was thought to be caused by the reactivation of a latent infection, but several studies have demonstrated that Pneumocystis jirovecii infection can be acquired de novo. On the basis of our results obtained from a
Autor:
Klára Hofštetrová, Magdalena Uzlíková, Pavla Tůmová, Karin Troell, Eva Nohýnková, Staffan G. Svärd
Publikováno v:
Experimental parasitology. 124(2)
This study is a thorough examination of the effects of the DNA polymerase inhibitor aphidicolin on the nuclear cycle and cell cycle progression characteristics, as well as their reversibility, in Giardia intestinalis. Giardia trophozoites are arreste