Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Magdalena Teufl"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1745 (2021)
Disabled 1 (Dab1) is an adapter protein for very low density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2) and an integral component of the Reelin pathway which orchestrates neuronal layering during embryonic brain development
Externí odkaz:
https://doaj.org/article/dadd63ce56a143199c78ed342d04318c
Autor:
Anja Wagner, Edgar Galicia-Andrés, Magdalena Teufl, Lukas Gold, Christian Obinger, Peter Sykacek, Chris Oostenbrink, Michael W. Traxlmayr
Publikováno v:
Biochemistry. 61:2049-2062
The epidermal growth factor receptor (EGFR) is frequently mutated in human cancer, most notably non-small-cell lung cancer and glioblastoma. While many frequently occurring EGFR mutations are known to confer constitutive EGFR activation, the situatio
Autor:
Jorge Iván Castillo-Quan, Michael J. Steinbaugh, Laura Paulette Fernández-Cárdenas, Nancy K. Pohl, Ziyun Wu, Feimei Zhu, Natalie Moroz, Veronica Teixeira, Monet S. Bland, Nicolas J. Lehrbach, Lorenza Moronetti, Magdalena Teufl, T. Keith Blackwell
Publikováno v:
Science advances. 9(1)
Although excessive lipid accumulation is a hallmark of obesity-related pathologies, some lipids are beneficial. Oleic acid (OA), the most abundant monounsaturated fatty acid (FA), promotes health and longevity. Here, we show that OA benefits Caenorha
Autor:
Jorge Iván Castillo-Quan, Michael J. Steinbaugh, L. Paulette Fernández-Cárdenas, Nancy K. Pohl, Ziyun Wu, Feimei Zhu, Natalie Moroz, Veronica Teixeira, Monet S. Bland, Nicolas J. Lehrbach, Lorenza E. Moronetti Mazzeo, Magdalena Teufl, T. Keith Blackwell
Although excessive lipid accumulation is a hallmark of obesity-related pathologies, some lipids are beneficial. Oleic acid (OA), the most abundant monounsaturated fatty acid (FA), promotes health and longevity. Here we show that OA benefits C. elegan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc24efea0147a96863409f7428d5d0cc
https://doi.org/10.1101/2022.06.15.496302
https://doi.org/10.1101/2022.06.15.496302
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2491
Yeast surface display is a powerful protein engineering technology that is extensively used to improve various properties of proteins, including affinity, specificity, and stability or even to add novel functions (usually ligand binding). Apart from
Publikováno v:
ACS synthetic biology. 11(3)
In addition to its biological function, the stability of a protein is a major determinant for its applicability. Unfortunately, engineering proteins for improved functionality usually results in destabilization of the protein. This so-called stabilit
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622841
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e43498ad9d81895f45f3e7ab72c5b58
https://doi.org/10.1007/978-1-0716-2285-8_9
https://doi.org/10.1007/978-1-0716-2285-8_9
Autor:
Michael W. Traxlmayr, Anja Wagner, Peter Sykacek, Manfred Lehner, Lukas Gold, Christian Obinger, Magdalena Teufl
Publikováno v:
Journal of molecular biology. 433(22)
Drug resistance poses a major challenge for targeted cancer therapy. To be able to functionally screen large randomly mutated target gene libraries for drug resistance mutations, we developed a biochemically defined high-throughput assay termed Phosp