Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Magdalena Szymanska"'
Autor:
Magdalena Szymanska, Agnieszka Blitek
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Angiogenesis is important for endometrial remodeling in mature females. The endometrium synthesizes high amounts of prostacyclin (PGI2) but the role of PGI2 in angiogenesis-related events in this tissue was not fully described. In the presen
Externí odkaz:
https://doaj.org/article/030962c0aaab42dcad45a1fd24c1ccc2
Publikováno v:
Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Human granulosa-lutein cells (hGLCs) amply express sirtuin-1 (SIRT1), a NAD + -dependent deacetylase that is associated with various cellular functions. SIRT1 was shown to elevate cAMP on its own and additively with human chorioni
Externí odkaz:
https://doaj.org/article/3f4234d567c645339fabec65f8213552
Publikováno v:
Animals, Vol 12, Iss 17, p 2237 (2022)
Although prostacyclin (PGI2) has been well described as a regulator of smooth muscle activity, limited data are available concerning its role in the myometrium of pigs. The present research aimed to examine profiles of PGI2 synthase (PTGIS) and PGI2
Externí odkaz:
https://doaj.org/article/6ae6544d0f3c4856a9f9856a3ed6a0ef
Autor:
Magdalena Szymanska, Agnieszka Blitek
Publikováno v:
Annals of Animal Science. 23:439-448
The present study aimed to examine the effect of impaired progesterone (P4) synthesis, observed in gilts with gonadotropin-induced estrus, on the uterine expression of receptors important for pregnancy establishment. Twenty prepubertal gilts received
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8857af2d3ffb865918a0748c9f42001b
https://doi.org/10.2478/aoas-2022-0076
https://doi.org/10.2478/aoas-2022-0076
Autor:
Rina Meidan, Magdalena Szymanska
Publikováno v:
Biology of Reproduction. 108:720-730
Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide–dependent deacetylase that modifies gene expression through histone deacetylation. It also deacetylates nonhistone substrates, e.g., tumor suppressor p53, NOS3, HIF1A, NFKB, FOXO3a, PGC-1α,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ea02f0eec0a175c44049dbe383feb8e
https://doi.org/10.1093/biolre/ioad026
https://doi.org/10.1093/biolre/ioad026
Publikováno v:
Reproductive Biology. 20:273-281
Sirtuin-1 (SIRT1), a NAD+-dependent deacetylase, is present in the ovarian granulosa cells (GCs) of various species. This study examined the regulation of SIRT1 expression in human granulosa-lutein cells (hGLCs). Two different, structurally unrelated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba58c84c9e837291a7444de6dfe0710
https://doi.org/10.1016/j.repbio.2020.07.010
https://doi.org/10.1016/j.repbio.2020.07.010
Autor:
Magdalena Szymanska, Agnieszka Blitek
Publikováno v:
Theriogenology. 127:88-101
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor family of ligand-dependent transcription factors. PPARs are important regulators of glucose and fatty acid metabolism, apoptosis, angiogenesis, cell proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f2957d765bbf7dd97ee405ca8803cc
https://doi.org/10.1016/j.theriogenology.2019.01.002
https://doi.org/10.1016/j.theriogenology.2019.01.002
Autor:
Magdalena Szymanska, Agnieszka Blitek
Background: The hormonal control of ovulation has become a standard procedure in the swine industry. However, exogenous gonadotropins can be detrimental to reproductive function, affecting follicle development, corpus luteum formation, and embryo dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba292c57edf34bdaa3e1894c8a676961
https://doi.org/10.21203/rs.3.rs-299567/v1
https://doi.org/10.21203/rs.3.rs-299567/v1
Autor:
Rina Meidan, Nina Schmid, Artur Mayerhofer, Kim-Gwendolyn Dietrich, Doris Mayr, Ignasi Forné, Magdalena Szymanska, Alexander Burges
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2047, p 2047 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Sirtuins (SIRTs) are NAD+-dependent deacetylases that regulate proliferation and cell death. In the human ovary, granulosa cells express sirtuin 1 (SIRT1), which has also been detected in human tumors derived from granulosa cells, i.e., granulosa cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd05533800a40d355743143c69dc3a2
https://pubmed.ncbi.nlm.nih.gov/33669567
https://pubmed.ncbi.nlm.nih.gov/33669567
Autor:
Ketan Shrestha, Avi Harlev, Tatiana Kisliouk, Sarah Manthe, Rina Meidan, Eliezer Girsh, Magdalena Szymanska
Publikováno v:
Biology of reproduction. 104(2)
Endothelin-2 (EDN2) expression in granulosa cells was previously shown to be highly dependent on the hypoxic mediator, hypoxia inducible factor 1 alpha (HIF1A). Here, we investigated whether sirtuin-1 (SIRT1), by deacetylating HIF1A and class III his
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d0a2d63bc8796e3527518daef1cb53
https://pubmed.ncbi.nlm.nih.gov/33112382
https://pubmed.ncbi.nlm.nih.gov/33112382