Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Magdalena Steinrueck"'
Autor:
Mato Lagator, Srdjan Sarikas, Magdalena Steinrueck, David Toledo-Aparicio, Jonathan P Bollback, Calin C Guet, Gašper Tkačik
Publikováno v:
eLife, Vol 11 (2022)
Predicting function from sequence is a central problem of biology. Currently, this is possible only locally in a narrow mutational neighborhood around a wildtype sequence rather than globally from any sequence. Using random mutant libraries, we devel
Externí odkaz:
https://doaj.org/article/50f68b595e8143fc96311c7d7b58db73
Autor:
Magdalena Steinrueck, Călin C Guet
Publikováno v:
eLife, Vol 6 (2017)
How the organization of genes on a chromosome shapes adaptation is essential for understanding evolutionary paths. Here, we investigate how adaptation to rapidly increasing levels of antibiotic depends on the chromosomal neighborhood of a drug-resist
Externí odkaz:
https://doaj.org/article/1e4a480e98b7409c8da8e40a08ec89a5
Autor:
Andrea Perne, Markus K Muellner, Magdalena Steinrueck, Nils Craig-Mueller, Julia Mayerhofer, Ilse Schwarzinger, Mathew Sloane, Iris Z Uras, Gregor Hoermann, Sebastian M B Nijman, Matthias Mayerhofer
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8292 (2009)
BACKGROUND:Cardiac glycosides are Na(+)/K(+)-pump inhibitors widely used to treat heart failure. They are also highly cytotoxic, and studies have suggested specific anti-tumor activity leading to current clinical trials in cancer patients. However, a
Externí odkaz:
https://doaj.org/article/56333376f154435899319fc91d9ee048
Autor:
Iris Z. Uras, Andrea Perne, Markus K Muellner, Nils Craig-Mueller, Julia Mayerhofer, Magdalena Steinrueck, Matthias Mayerhofer, Sebastian M.B. Nijman, Mathew A. Sloane, Gregor Hoermann, Ilse Schwarzinger
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 12, p e8292 (2009)
PLoS ONE, Vol 4, Iss 12, p e8292 (2009)
Background Cardiac glycosides are Na+/K+-pump inhibitors widely used to treat heart failure. They are also highly cytotoxic, and studies have suggested specific anti-tumor activity leading to current clinical trials in cancer patients. However, a def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fb13d6154cb5a68d6ce4995dd4c793
http://ora.ox.ac.uk/objects/uuid:6701c3be-550d-4521-9713-a493a5618c4c
http://ora.ox.ac.uk/objects/uuid:6701c3be-550d-4521-9713-a493a5618c4c