Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Magdalena Smolik"'
Publikováno v:
Farmacja Polska, Vol 78, Iss 5, Pp 235-248 (2022)
Cannabis sp. or hemp is a plant that has been used extensively for centuries, both as an excellent source of fibers and oil, but also - thanks to the content of compounds called phytocannabinoids, acts as a plant for medicinal applications. Determina
Externí odkaz:
https://doaj.org/article/7e7d77a40a1d4f53b2a90c483b0f52e8
Autor:
Anna Kurpińska, Joanna Suraj-Prażmowska, Marta Stojak, Joanna Jarosz, Łukasz Mateuszuk, Ewa Niedzielska-Andres, Magdalena Smolik, Joanna Wietrzyk, Ivars Kalvins, Maria Walczak, Stefan Chłopicki
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Protein disulphide isomerases (PDIs) play an important role in cancer progression. However, the relative contribution of the various isoforms of PDI in tumorigenesis is not clear. Methods The content of PDI isoforms in 22 cancer c
Externí odkaz:
https://doaj.org/article/fe337fe835924b6da3d2707ee7bd8775
Publikováno v:
Farmacja Polska, Vol 76, Iss 10, Pp 562-574 (2020)
The proper functioning of all living organisms depends on the supply of essential nutrients from the outside and the removal of harmful toxic compounds from the cells by primary and secondary membrane transport. The ABC transporters constitute the la
Externí odkaz:
https://doaj.org/article/31b7bf89af4e49858b8cab2cc3ae7985
Autor:
Karolina Pytka, Monika Głuch-Lutwin, Elżbieta Żmudzka, Kinga Sałaciak, Agata Siwek, Katarzyna Niemczyk, Maria Walczak, Magdalena Smolik, Adrian Olczyk, Adam Gałuszka, Jarosław Śmieja, Barbara Filipek, Jacek Sapa, Marcin Kołaczkowski, Katarzyna Pańczyk, Anna Waszkielewicz, Henryk Marona
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Numerous studies have proven that both stimulation and blockade of 5-HT1A and the blockade of 5-HT7 receptors might cause the anxiolytic-like effects. Biased agonists selectively activate specific signaling pathways. Therefore, they might offer novel
Externí odkaz:
https://doaj.org/article/8dd1f0a7d698424791fe883f5d6e889d
Autor:
Monika Marcinkowska, Barbara Mordyl, Nikola Fajkis-Zajaczkowska, Agata Siwek, Tadeusz Karcz, Alicja Gawalska, Adam Bucki, Paweł Żmudzki, Anna Partyka, Magdalena Jastrzębska-Więsek, Bartosz Pomierny, Maria Walczak, Magdalena Smolik, Karolina Pytka, Kamil Mika, Magdalena Kotańska, Marcin Kolaczkowski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb72866cc7a51b1faf9300381925753d
https://ruj.uj.edu.pl/xmlui/handle/item/305937
https://ruj.uj.edu.pl/xmlui/handle/item/305937
Autor:
Gabriela Mazur, Katarzyna Pańczyk‐Straszak, Anna Rapacz, Jan Kiszela, Magdalena Smolik, Maciej Gawlik, Maria Walczak, Joanna Czekajewska, Celina Poloczek, Elżbieta Karczewska, Ewa Żesławska, Wojciech Nitek, Anna Niedbał, Joanna Leśniak, Katarzyna Ciapala, Katarzyna Pawlik, Joanna Mika, Anna M. Waszkielewicz
A series of ten aminoalkanol derivatives of 5-chloro-2- or 5-chloro-4-methylxanthone was synthetized and evaluated for anticonvulsant properties (MES test, mice, intraperitoneal) and compared with neurotoxicity rotarod test (NT, mice, i.p.). The best
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f6147c433b318056421569db4f1592
https://ruj.uj.edu.pl/xmlui/handle/item/297624
https://ruj.uj.edu.pl/xmlui/handle/item/297624
Autor:
Monika, Marcinkowska, Barbara, Mordyl, Nikola, Fajkis-Zajaczkowska, Agata, Siwek, Tadeusz, Karcz, Alicja, Gawalska, Adam, Bucki, Paweł, Żmudzki, Anna, Partyka, Magdalena, Jastrzębska-Więsek, Bartosz, Pomierny, Maria, Walczak, Magdalena, Smolik, Karolina, Pytka, Kamil, Mika, Magdalena, Kotańska, Marcin, Kolaczkowski
Publikováno v:
European journal of medicinal chemistry. 247
There is clear evidence that the presence of inflammatory factors and impaired GABA-ergic neurotransmission in depressed patients is associated with poor clinical outcome. We designed hybrid molecules, bearing the GABA molecule assembled with chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9edbeffe28ba9055b680805846b793a
https://pubmed.ncbi.nlm.nih.gov/36603509
https://pubmed.ncbi.nlm.nih.gov/36603509
Autor:
Tomasz Sacha, Anna Kurpińska, Stefan Chlopicki, Maria Walczak, Agnieszka Zakrzewska, Joanna Suraj, Aleksander Kania, Magdalena Sternak, Magdalena Smolik, Ewa Niedzielska-Andres
Publikováno v:
Talanta. 194:1005-1016
The aim of this study was to develop and validate the novel microLC/MS-MRM method for the simultaneous quantification of six proteins: angiopoietin 2 (Angpt-2), soluble form of fms-like tyrosine kinase 1 (sFLT-1), plasminogen activator inhibitor 1 (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccef416d75068d5a5322f09e2732b932
https://doi.org/10.1016/j.talanta.2018.10.067
https://doi.org/10.1016/j.talanta.2018.10.067
Detailed assessment of the biotransformation of compounds and the activity of their metabolites is an extremely important element in the safety evaluation of a substance, both in preclinical and clinical studies. It should be noted that the metabolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7d3a44deaccf8044d6f6dcfb4673c0
https://ruj.uj.edu.pl/xmlui/handle/item/290384
https://ruj.uj.edu.pl/xmlui/handle/item/290384
Publikováno v:
Postępy Higieny i Medycyny Doświadczalnej, Vol 72, Pp 606-622 (2018)
ABC transporters are the largest family of transport proteins, which mediate the active translocation of a wide spectrum of molecules through the cell membrane, using energy from hydrolysis of ATP. They can act as importers (in Procaryota exclusively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9678eac22534540d7f131446f527e99
http://phmd.pl/gicid/pdf/01.3001.0012.1966
http://phmd.pl/gicid/pdf/01.3001.0012.1966