Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Magdalena Skunca"'
Autor:
Magdalena Skunca, Sarah G. Buxbaum, Natzi Sakalihasan, Olivier D. Defawe, Gerard Tromp, Raymond Limet, Jane M. Olson, Claudette Arthur, Alain Verloes, Hidenori Shibamura, Gerard Pals, Clarissa van Vlijmen-van Keulen, Alan G. Lossing, Marjorie Burnett, Gerald L. MacKean, Taijiro Sueda, Toru Ogata, Helena Kuivaniemi, Doreen M. Dudek
Publikováno v:
Circulation. 109:2103-2108
Background— Abdominal aortic aneurysm (AAA) is a relatively common disease, with 1% to 2% of the population harboring aneurysms. Genetic risk factors are likely to contribute to the development of AAAs, although no such risk factors have been ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19f10a24947f48abf09fc651bb1ac1b2
https://doi.org/10.1161/01.cir.0000127857.77161.a1
https://doi.org/10.1161/01.cir.0000127857.77161.a1
Autor:
Helena Kuivaniemi, Gerard Tromp, Guy M. Lenk, Magdalena Skunca, Ramon Berguer, Zoran Gatalica
Publikováno v:
Annals of the New York Academy of Sciences. 1085:360-362
Abdominal aortic aneurysms (AAA) are the thirteenth cause of death in the United States. The etiology of the disease is yet largely unknown, although several environmental risk factors (e.g., smoking) have been identified and the search for finding g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e015850f5658be3b224f4682f67f03c
https://doi.org/10.1196/annals.1383.041
https://doi.org/10.1196/annals.1383.041
Autor:
Magdalena Skunca, Jeffrey A. Moshier, Sita M. Boppana, Wei Wu, Frank J. Rauscher, Julie Dosescu
Publikováno v:
Nucleic Acids Research. 24:1149-1157
The importance of ornithine decarboxylase (ODC) to cell proliferation is underscored by the complex array of cell-specific mechanisms invoked to regulate its synthesis and activity. Misregulation of ODC has severe negative consequences on normal cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995f67850a35b0b0fefcc608623f71f5
https://doi.org/10.1093/nar/24.6.1149
https://doi.org/10.1093/nar/24.6.1149
Autor:
David L. Osborne, Sandra J. Friezner Degen, Richard L. Wagner, Margaret A. Flanagan, Jeffrey D. Gilbert, Gordon D. Luk, Julie Dosescu, Gregg Polidori, Mary C. Fitzgerald, Magdalena Skunca, Jeffrey A. Moshier
Publikováno v:
Nucleic Acids Research. 20:2581-2590
Overexpression of the ornithine decarboxylase (ODC) gene may be important to the development and maintenance of colonic neoplasms, as well as tumors in general. In this study, we examined the promoter elements governing constitutive expression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43339aedccf5948562915386495b3b4a
https://doi.org/10.1093/nar/20.10.2581
https://doi.org/10.1093/nar/20.10.2581
Autor:
Qing Lu, Natzi Sakalihasan, Toru Ogata, Gerard Tromp, Antonio R Parrado, Taijiro Sueda, Raymond Limet, Magdalena Skunca, Helena Kuivaniemi, Katrina A.B. Goddard, Wayne D. Lancaster, Gerald L. MacKean, Hidenori Shibamura, Claudette Arthur, Lucie Gregoire
Publikováno v:
Annals of the New York Academy of Sciences. 1085
Chronic inflammation and autoimmunity likely contribute to the pathogenesis of abdominal aortic aneurysms (AAAs). The aim of this study was to investigate the role of autoimmunity in the etiology of AAAs using a genetic association study approach wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74250c4c453366d1340c1338ce91071
https://pubmed.ncbi.nlm.nih.gov/17182961
https://pubmed.ncbi.nlm.nih.gov/17182961
Autor:
Natzi Sakalihasan, Lucie Gregoire, Antonio R Parrado, Raymond Limet, Helena Kuivaniemi, Hidenori Shibamura, Taijiro Sueda, Wayne D. Lancaster, Gerald L. MacKean, Qing Lu, Magdalena Skunca, Katrina A.B. Goddard, Claudette Arthur, Toru Ogata, Gerard Tromp
Publikováno v:
BMC Medical Genetics
BMC Medical Genetics, Vol 7, Iss 1, p 67 (2006)
BMC Medical Genetics, Vol 7, Iss 1, p 67 (2006)
Background Chronic inflammation and autoimmunity likely contribute to the pathogenesis of abdominal aortic aneurysms (AAAs). The aim of this study was to investigate the role of autoimmunity in the etiology of AAAs using a genetic association study a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930752ef803b3df2014ae6f445837b1c
https://doi.org/10.1186/1471-2350-7-67
https://doi.org/10.1186/1471-2350-7-67
Autor:
Jeffrey A. Moshier, Adhip P.N. Majumdar, Hairong Geng, Magdalena Skunca, Julie Dosescu, Paul H. Naylor
Publikováno v:
Carcinogenesis. 21(4)
Ornithine decarboxylase (ODC) overexpressed from a heterologous promoter drives the tumorigenic transformation of NIH 3T3 cells and provides a model to investigate the underlying molecular mechanisms. These transformed cells, designated NODC cells, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956498e7aaf11ac3a01d004d20cd63e6
https://pubmed.ncbi.nlm.nih.gov/10753187
https://pubmed.ncbi.nlm.nih.gov/10753187
Autor:
Mitchell R. Smith, Cartha W. Naylor, Magdalena Skunca, Jeffrey A. Moshier, Julie Dosescu, Paul H. Naylor, Milton G. Mutchnick
Publikováno v:
International journal of immunopharmacology. 18(5)
Thymosin alpha 1 (T alpha 1) is an immune modulatory peptide which has been evaluated in a variety of clinical trials. Although no in vivo adverse effects, including enhancement of tumor growth, have been noted, in vitro studies suggesting a role for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dcc9352525107fe7e97155011a0d702
https://pubmed.ncbi.nlm.nih.gov/8933211
https://pubmed.ncbi.nlm.nih.gov/8933211
Publikováno v:
Gene. 59:47-53
The gene coding for subunit III of CFO-ATPase complex (atpH gene) has been localized on the soybean chloroplast genome by heterologous hybridization with the atpH gene of wheat chloroplast. The gene, 243 bp in length, is located in a 7.5-kb BamHI fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02df35990104f504ec04111809ef2b32
https://doi.org/10.1016/0378-1119(87)90265-4
https://doi.org/10.1016/0378-1119(87)90265-4
Autor:
Katariina Helin, Monique van der Voet, Juha Jääskeläinen, Moumita Biswas, Doreen M. Dudek, Gerard Tromp, Eira Leinonen, Juha Hernesniemi, Magdalena Skunca, Jane M. Olson, Mika Niemelä, Helena Kuivaniemi, Antti Ronkainen
Publikováno v:
The American Journal of Human Genetics. (3):564-571
We recently reported a two-stage genomewide screen of 48 sib pairs affected with intracranial aneurysms (IAs) that revealed suggestive linkage to chromosome 19q13, with a LOD score of 2.58. The region supporting linkage spanned approximately 22 cM. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2daa0b4365ef20697504c8c542c6c950