Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Magdalena Sips"'
Autor:
Anna Zakrzewicz, Katrien Vanderheyden, Yad Galaly, Simon Feldhoff, Magdalena Sips, Maximilian Brinkhaus, Ritva Tikkanen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The neonatal Fc receptor (FcRn) is important for numerous cellular processes that involve antibody recycling and trafficking. A major function of FcRn is IgG recycling and half-life prolongation, and FcRn blockade results in a reduction of autoantibo
Externí odkaz:
https://doaj.org/article/d8db3bf2f6a64a55929016d2d491384e
Autor:
Jeffrey T. Guptill, John W. Sleasman, Sophie Steeland, Magdalena Sips, Deborah Gelinas, Hans de Haard, Antoine Azar, Kevin L. Winthrop
Publikováno v:
Autoimmunity, Vol 55, Iss 8, Pp 620-631 (2022)
Antagonism of the neonatal Fc receptor (FcRn) by efgartigimod has been studied in several autoimmune diseases mediated by immunoglobulin G (IgG) as a therapeutic approach to remove pathogenic IgGs. Whereas reduction of pathogenic titres has demonstra
Externí odkaz:
https://doaj.org/article/10031c764e23401a8e3976f37b1c6169
Autor:
Maximilian Brinkhaus, Erwin Pannecoucke, Elvera J. van der Kooi, Arthur E. H. Bentlage, Ninotska I. L. Derksen, Julie Andries, Bianca Balbino, Magdalena Sips, Peter Ulrichts, Peter Verheesen, Hans de Haard, Theo Rispens, Savvas N. Savvides, Gestur Vidarsson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Disrupting the association between the Immunoglobulin G constant fragment (Fc) and the neonatal Fc receptor (FcRn) by engineered antibodies is a promising strategy to reduce autoantibody levels in autoimmune diseases. Here authors show that the varia
Externí odkaz:
https://doaj.org/article/6899a98a2d164434bf23cc999f69e473
Autor:
Magdalena Sips, Sarah Gerlo, Laura De Clercq, Esteban A. Gomez, Romain A. Colas, Jesmond Dalli, Linos Vandekerckhove
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Introduction: To date, with no prophylactic human immunodeficiency virus (HIV) vaccine available, HIV incidence rates remain undefeated. Despite full virological suppression, HIV+ individuals exhibit a higher rate of cardiovascular disorders
Externí odkaz:
https://doaj.org/article/bb8a17d4101f4c3cb52dad01a8588d6a
Autor:
Maud Maho-Vaillant, Magdalena Sips, Marie-Laure Golinski, Gestur Vidarsson, Matthias Goebeler, Johanna Stoevesandt, Zsuzsanna Bata-Csörgő, Bianca Balbino, Peter Verheesen, Pascal Joly, Michael Hertl, Sébastien Calbo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundImmunoglobulin G (IgG) levels are maintained by the IgG-recycling neonatal Fc-receptor (FcRn). Pemphigus vulgaris and pemphigus foliaceus are debilitating autoimmune disorders triggered by IgG autoantibodies against mucosal and epidermal de
Externí odkaz:
https://doaj.org/article/380a8e49202e4cc48ab5e7f9dc89f979
Autor:
Clarissa Van Hecke, Wim Trypsteen, Eva Malatinkova, Ward De Spiegelaere, Karen Vervisch, Sofie Rutsaert, Sabine Kinloch-de Loes, Magdalena Sips, Linos Vandekerckhove
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 443-454 (2019)
Background: A wide range of host restriction factors (RF) become upregulated upon HIV-1 infection to suppress viral infectivity and may aid viremic control in vivo. This cross-sectional study evaluated HIV-1 RFs and dependency factors in HIV infected
Externí odkaz:
https://doaj.org/article/1136f58e76a74e148cdf17df17ae635c
Publikováno v:
Journal of Virus Eradication, Vol 4, Iss 1, Pp 55-59 (2018)
For the second time, the HIV Cure Research Center (HCRC) at Ghent University organised the HIV Cure and Reservoir Symposium, in Ghent, Belgium, where in this two-day conference, virologists, molecular biologists, immunologists and clinicians presente
Externí odkaz:
https://doaj.org/article/1b95be4bdd4e4614adc25c7cdfca2bfb
Publikováno v:
Journal of Virus Eradication, Vol 3, Iss 1, Pp 66-68 (2017)
The HIV Cure Research Center (HCRC) in Ghent organised the first HIV Reservoir Characterization Symposium, and brought together virologists, molecular biologists, immunologists and clinicians to discuss the most recent developments in HIV reservoir c
Externí odkaz:
https://doaj.org/article/d6148db32d1a4d2e9b6ce356e944fae6
Autor:
Olga Ostrovskaya, Magdalena Sips, Peter Ulrichts, Lance Trainor, Peter Verheesen, Ivaylo Stoykov
Publikováno v:
SKIN The Journal of Cutaneous Medicine. 7:s193
Autor:
Sofie Rutsaert, Ward De Spiegelaere, Karen Vervisch, Linos Vandekerckhove, Sabine Kinloch-de Loes, Magdalena Sips, Wim Trypsteen, Clarissa Van Hecke, Eva Malatinkova
Publikováno v:
EBIOMEDICINE
EBioMedicine
EBioMedicine
Background: A wide range of host restriction factors (RF) become upregulated upon HIV-1 infection to suppress viral infectivity and may aid viremic control in vivo. This cross-sectional study evaluated HIV-1 RFs and dependency factors in HIV infected