Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Magdalena Sedek"'
Autor:
Ger J. Strous, Ana Da Silva Almeida, Joyce Putters, Julia Schantl, Magdalena Sedek, Johan A. Slotman, Tobias Nespital, Gerco C. Hassink, Jan A. Mol
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The GHR signaling pathway plays important roles in growth, metabolism, cell cycle control, immunity, homeostatic processes, and chemoresistance via both the JAK/STAT and the SRC pathways. Dysregulation of GHR signaling is associated with various dise
Externí odkaz:
https://doaj.org/article/f54837c6dbd34bc3a5f7c91870b0008a
Autor:
Eelke P. Béguin, Małgorzata A. Przeradzka, Esmée F.J. Janssen, Henriët Meems, Magdalena Sedek, Carmen van der Zwaan, Koen Mertens, Maartje van den Biggelaar, Alexander B. Meijer, Marjon J. Mourik
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/56fb56d3eb4d47fcbad2cc1739156f82
Autor:
Nicoletta Sorvillo, Robin B. Hartholt, Esther Bloem, Magdalena Sedek, Anja ten Brinke, Carmen van der Zwaan, Floris P. van Alphen, Alexander B. Meijer, Jan Voorberg
Publikováno v:
Haematologica, Vol 101, Iss 3 (2016)
It has been proposed that von Willebrand factor might affect factor VIII immunogenicity by reducing factor VIII uptake by antigen presenting cells. Here we investigate the interaction of recombinant von Willebrand factor with immature monocyte-derive
Externí odkaz:
https://doaj.org/article/b28ed143071e4b9a842230f9a440e7b1
Autor:
Carmen van der Zwaan, Eelke P. Béguin, Esmée F.J. Janssen, Koen Mertens, Magdalena Sedek, Maartje van den Biggelaar, Marjon J. Mourik, Alexander B. Meijer, Henriet Meems, Małgorzata A. Przeradzka
Publikováno v:
Haematologica. 105:e133-e137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416e7ef32c1c0bac11515a9346d6a3d4
https://doi.org/10.3324/haematol.2018.210682
https://doi.org/10.3324/haematol.2018.210682
Publikováno v:
Journal of Biological Chemistry. 289:65-73
Growth hormone (GH) signaling is required for promoting longitudinal body growth, stem cell activation, differentiation, and survival and for regulation of metabolism. Failure to adequately regulate GH signaling leads to disease: excessive GH signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d20bfc5f47c9e68d0116311e3089bc
https://doi.org/10.1074/jbc.m113.523373
https://doi.org/10.1074/jbc.m113.523373
Autor:
Ger J. Strous, Magdalena Sedek
Publikováno v:
Biochemical Journal. 453:231-239
Jak2 (Janus kinase 2) initiates the signal transduction of many cytokine receptors. We discovered that Jak2 is SUMOylated on multiple lysine residues by SUMO2/3 (small ubiquitin-related modifier 2/3) chains. Analysis of Jak2 mutants revealed that Jak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e650359a6f4b36355e31e8222b16ea63
https://doi.org/10.1042/bj20121375
https://doi.org/10.1042/bj20121375