Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Magdalena Podlacha"'
Autor:
Magdalena Podlacha, Lidia Gaffke, Łukasz Grabowski, Jagoda Mantej, Michał Grabski, Małgorzata Pierzchalska, Karolina Pierzynowska, Grzegorz Węgrzyn, Alicja Węgrzyn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract One of the hopes for overcoming the antibiotic resistance crisis is the use of bacteriophages to combat bacterial infections, the so-called phage therapy. This therapeutic approach is generally believed to be safe for humans and animals as p
Externí odkaz:
https://doaj.org/article/df9c80bb398e4f7098d62910ccb6774c
Autor:
Łukasz Grabowski, Karolina Pierzynowska, Katarzyna Kosznik-Kwaśnicka, Małgorzata Stasiłojć, Grażyna Jerzemowska, Alicja Węgrzyn, Grzegorz Węgrzyn, Magdalena Podlacha
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe problem of antibiotic resistance is a global one, involving many industries and entailing huge financial outlays. Therefore, the search for alternative methods to combat drug-resistant bacteria has a priority status. Great potential i
Externí odkaz:
https://doaj.org/article/c0dd1f53083f43f5be1656282ed525f4
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The appearance of bacteria resistant to most or even all known antibiotics has become a serious medical problem. One such promising and effective alternative form of therapy may be the use of phages, the administration of which is considered to be sa
Externí odkaz:
https://doaj.org/article/8f783653ee5b4d24965bbee1f45c41aa
Autor:
Katarzyna Kosznik-Kwaśnicka, Magdalena Podlacha, Łukasz Grabowski, Małgorzata Stasiłojć, Alicja Nowak-Zaleska, Karolina Ciemińska, Zuzanna Cyske, Aleksandra Dydecka, Lidia Gaffke, Jagoda Mantej, Dorota Myślińska, Agnieszka Necel, Karolina Pierzynowska, Ewa Piotrowska, Edyta Radzanowska-Alenowicz, Estera Rintz, Krzysztof Sitko, Gracja Topka-Bielecka, Grzegorz Węgrzyn, Alicja Węgrzyn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Phage therapy is a promising alternative treatment of bacterial infections in human and animals. Nevertheless, despite the appearance of many bacterial strains resistant to antibiotics, these drugs still remain important therapeutics used in human an
Externí odkaz:
https://doaj.org/article/610636f6eaa940bdaafc1decc571dca4
Autor:
Magdalena Podlacha, Karolina Pierzynowska, Lidia Gaffke, Grażyna Jerzemowska, Ewa Piotrowska, Grzegorz Węgrzyn
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 23, Iss , Pp 100482- (2022)
Background: Huntington's disease (HD) is a genetic neurodegenerative disorder characterized by a triad of cognitive, psychiatric and motor symptoms. One of the main mechanisms of the disease, besides the aggregation of mutant proteins, is the chronic
Externí odkaz:
https://doaj.org/article/9226154a6e494b6d99d986928f2a4dbc
Autor:
Magdalena Żabińska, Lidia Gaffke, Patrycja Bielańska, Magdalena Podlacha, Estera Rintz, Zuzanna Cyske, Grzegorz Węgrzyn, Karolina Pierzynowska
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 704 (2023)
Mucopolysaccharidoses (MPS) are rare genetic disorders belonging to the lysosomal storage diseases. They are caused by mutations in genes encoding lysosomal enzymes responsible for degrading glycosaminoglycans (GAGs). As a result, GAGs accumulate in
Externí odkaz:
https://doaj.org/article/72b76420239a4d05b4ecaac03a97de37
Publikováno v:
Antibiotics, Vol 11, Iss 12, p 1787 (2022)
Previous studies indicated that the use of a phage cocktail, composed of bacteriophages vB_SenM-2 and vB_Sen-TO17, is effective in killing cells of Salmonella enterica serovars Typhimurium and Enteritidis in vitro and in the Galleria mellonella anima
Externí odkaz:
https://doaj.org/article/5eb3a73ed1544c44aaf9175d2105ee88
Autor:
Marta Tomczyk, Alicja Braczko, Paulina Mierzejewska, Magdalena Podlacha, Oliwia Krol, Patrycja Jablonska, Agata Jedrzejewska, Karolina Pierzynowska, Grzegorz Wegrzyn, Ewa M. Slominska, Ryszard T. Smolenski
Publikováno v:
Cells, Vol 11, Iss 17, p 2662 (2022)
Huntington’s disease (HD) is a rare neurodegenerative disease that is accompanied by skeletal muscle atrophy and cardiomyopathy. Tissues affected by HD (central nervous system [CNS], skeletal muscle, and heart) are known to suffer from deteriorated
Externí odkaz:
https://doaj.org/article/4c55924b31554778a965e3a4c4a6a0a5
Autor:
Karolina Pierzynowska, Lidia Gaffke, Elżbieta Jankowska, Estera Rintz, Julia Witkowska, Ewa Wieczerzak, Magdalena Podlacha, Grzegorz Węgrzyn
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
In this study, we have asked whether proteasome composition and function are affected in cells derived from patients suffering from all types of mucopolysaccharidosis (MPS), an inherited metabolic disease caused by accumulation of undegraded glycosam
Externí odkaz:
https://doaj.org/article/ea6b7f889bcd489f9c0dac6dabfece65
Autor:
Natalia Miękus, Krystian Marszałek, Magdalena Podlacha, Aamir Iqbal, Czesław Puchalski, Artur H. Świergiel
Publikováno v:
Molecules, Vol 25, Iss 17, p 3804 (2020)
The broad spectrum of the mechanism of action of immune-boosting natural compounds as well as the complex nature of the food matrices make researching the health benefits of various food products a complicated task. Moreover, many routes are involved
Externí odkaz:
https://doaj.org/article/a3147f09f0644ae8957bbd6d56aac537