iNOS is necessary for GBP-mediated T. gondii clearance in murine macrophages via vacuole nitration and intravacuolar network collapse

Autor: Xiao-Yu Zhao, Samantha L. Lempke, Jan C. Urbán Arroyo, Isabel G. Brown, Bocheng Yin, Magdalena M. Magaj, Nadia K. Holness, Jamison Smiley, Stefanie Redemann, Sarah E. Ewald

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Abstract Toxoplasma gondii is an obligate intracellular parasite of rodents and humans. Interferon-inducible guanylate binding proteins (GBPs) are mediators of T. gondii clearance, however, this mechanism is incomplete. Here, using automated spatiall

Externí odkaz: https://doaj.org/article/6d37669bd768444090335bf5da6cab31

Author response: Ndc1 drives nuclear pore complex assembly independent of membrane biogenesis to promote nuclear formation and growth

Autor: Michael Sean Mauro, Gunta Celma, Vitaly Zimyanin, Magdalena M Magaj, Kimberley H Gibson, Stefanie Redemann, Shirin Bahmanyar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9426d4dab1e988b70ec80f4352a3f590
https://doi.org/10.7554/elife.75513.sa2

Lack of chromokinesin Klp-19 creates a more rigid midzone and affects force transmission during anaphase in C. elegans .

Autor: Zimyanin V; Department of Molecular Physiology and Biological Physics, University of Virginia, School of Medicine, Charlottesville, VA, USA.; Center for Membrane and Cell Physiology, University of Virginia School of Medicine, Charlottesville, VA, USA., Magaj M; Department of Molecular Physiology and Biological Physics, University of Virginia, School of Medicine, Charlottesville, VA, USA.; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA, USA., Yu CH; Department of Electrical and Computer Engineering, University of California, Santa Barbara, CA, USA., Gibney T; Department of Biology, University of Virginia, Charlottesville, VA, USA., Mustafa B; Molecular and Cellular Biology and School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA., Horton X; Department of Molecular Physiology and Biological Physics, University of Virginia, School of Medicine, Charlottesville, VA, USA.; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA, USA., Siller K; IT-Research Computing, University of Virginia, Charlottesville, VA, USA., Cueff L; CNRS, Univ Rennes, IGDR (Institut de Génétique et Dévelopement de Rennes) - UMR 6290, F-35000 Rennes, France., Bouvrais H; CNRS, Univ Rennes, IGDR (Institut de Génétique et Dévelopement de Rennes) - UMR 6290, F-35000 Rennes, France., Pécréaux J; CNRS, Univ Rennes, IGDR (Institut de Génétique et Dévelopement de Rennes) - UMR 6290, F-35000 Rennes, France., Needleman D; Molecular and Cellular Biology and School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Center for Computational Biology, Flatiron Institute, New York, NY, USA., Redemann S; Department of Molecular Physiology and Biological Physics, University of Virginia, School of Medicine, Charlottesville, VA, USA.; Center for Membrane and Cell Physiology, University of Virginia School of Medicine, Charlottesville, VA, USA.; Department of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 26. Date of Electronic Publication: 2023 Oct 26.