Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases.

Autor: Anand Sripada, Kapil Sirohi, Lidia Michalec, Lei Guo, Jerome T McKay, Sangya Yadav, Mukesh Verma, James Good, Donald Rollins, Magdalena M Gorska, Rafeul Alam

Publikováno v: PLoS Biology, Vol 19, Iss 3, p e3001063 (2021)

The function of Sprouty2 (Spry2) in T cells is unknown. Using 2 different (inducible and T cell-targeted) knockout mouse strains, we found that Spry2 positively regulated extracellular signal-regulated kinase 1/2 (ERK1/2) signaling by modulating the

Externí odkaz: https://doaj.org/article/9044a2f2a9d549eb95f03cf0a73e2f15

Modelling Asthma in Mice Using Common Aeroallergens

Autor: Bidisha Paul Chowdhury, Magdalena M. Gorska

Publikováno v: Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071623633

Aeroallergens are common inducers of asthma in humans and are widely used in experimental research to generate animal models of this disease. In this chapter, we describe four mouse models of aeroallergen-induced asthma. These models differ in type a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8680db2cad1fe17155d81ed4e4f42c26
https://europepmc.org/articles/PMC9721467/

JNK pathway and heat shock response mediate the survival of C26 colon carcinoma bearing mice fed with the mushroom Pleurotus eryngii var. eryngii without affecting tumor growth or cachexia

Autor: Alessandra Vitale, Giuseppe Venturella, Stefano Alfano, Celeste Caruso Bavisotto, Letizia Paladino, Valentina Di Felice, Francesca Rappa, Claudia Campanella, Antonella Marino Gammazza, Francesco Cappello, Magdalena M. Gorska, Filippo Macaluso, Maria Letizia Gargano, Rosario Barone

Publikováno v: Foodfunction. 12(7)

In the last few years, there has been emerging interest in developing treatments against human diseases using natural bioactive content. Here, the powder of the edible mushroom Pleurotus eryngii var. eryngii was mixed with the normal diet of mice bea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c910c560def5f108a1103bcc5d5b9f
https://pubmed.ncbi.nlm.nih.gov/33720221

Maternal diesel particle exposure promotes offspring asthma through NK cell–derived granzyme B

Autor: Jerica Lenberg, Magdalena M. Gorska, Bidisha Paul Chowdhury, Rafeul Alam, Qian Qian, Zehua Sun, Eric Vivier

Publikováno v: Journal of Clinical Investigation
J Clin Invest
Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, ⟨10.1172/JCI130324⟩
Journal of Clinical Investigation, 2020, ⟨10.1172/JCI130324⟩

Mothers living near high-traffic roads before or during pregnancy are more likely to have children with asthma. Mechanisms are unknown. Using a mouse model, here we showed that maternal exposure to diesel exhaust particles (DEP) predisposed offspring

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01121403906a669b295b2944e57f896

Pathological Changes in the Microstructure of Pale, Soft, Exudative (PSE) and Normal Turkey Breast Muscle

Autor: Dorota Wojtysiak, Magdalena M. Gorska

Publikováno v: Folia Biologica. 65:148-153

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e7316b8a3105313980fe184d4f85f7b
https://doi.org/10.3409/fb65_3.149