Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Magdalena Klanova"'
Autor:
Diana Malarikova, Radek Jorda, Kristyna Kupcova, Jana Senavova, Alexandra Dolnikova, Eva Pokorna, Dmitry Kazantsev, Kristina Nozickova, Dana Sovilj, Celine Bellanger, David Chiron, Ladislav Andera, Vladimir Krystof, Miroslav Strnad, Karel Helman, Magdalena Klanova, Marek Trneny, Ondrej Havranek, Pavel Klener
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-4 (2024)
Abstract Background Mantle cell lymphoma (MCL) is a chronically relapsing malignancy with deregulated cell cycle progression. We analyzed efficacy, mode of action, and predictive markers of susceptibility to palbociclib, an approved CDK 4/6 inhibitor
Externí odkaz:
https://doaj.org/article/66f0f83138da43c8bb386bfcf004df4c
Autor:
Pavle Krsmanovic, Heidi Mocikova, Kamila Chramostova, Magdalena Klanova, Marie Trnkova, Michal Pesta, Peter Laslo, Robert Pytlik, Tomas Stopka, Marek Trneny, Vit Pospisil
Publikováno v:
Cancers, Vol 14, Iss 9, p 2305 (2022)
Lymphoma with secondary central nervous system (CNS) involvement represents one of the most aggressive malignancies, with poor prognosis and high mortality. New diagnostic tools for its early detection, response evaluation, and CNS relapse prediction
Externí odkaz:
https://doaj.org/article/be6c400e29294972b8368cfc413f4dad
Autor:
Christopher R. Bolen, Magdalena Klanova, Marek Trneny, Laurie H. Sehn, Jie He, Jing Tong, Joseph N. Paulson, Eugene Kim, Umberto Vitolo, Alice Di Rocco, Günter Fingerle-Rowson, Tina Nielsen, Georg Lenz, Mikkel Z. Oestergaard
Publikováno v:
Haematologica, Vol 105, Iss 9 (2019)
Diffuse large B-cell lymphoma represents a biologically and clinically heterogeneous diagnostic category with well-defined cell-of-origin subtypes. Using data from the GOYA study (NCT01287741), we characterized the mutational profile of diffuse large
Externí odkaz:
https://doaj.org/article/777088f6dae24217ab48122ac29d0dd2
Autor:
Magdalena Klanova, Pavel Klener
Publikováno v:
Cancers, Vol 12, Iss 4, p 938 (2020)
The ability to inhibit mitochondrial apoptosis is a hallmark of B-cell non-Hodgkin lymphomas (B-NHL). Activation of mitochondrial apoptosis is tightly controlled by members of B-cell leukemia/lymphoma-2 (BCL-2) family proteins via protein-protein int
Externí odkaz:
https://doaj.org/article/da8fb8b8c37a4cae9c7a968d606c4724
Autor:
Pavel Klener, Magdalena Klanova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2081 (2020)
Non-Hodgkin lymphomas (NHL) are lymphoid tumors that arise by a complex process of malignant transformation of mature lymphocytes during various stages of differentiation. The WHO classification of NHL recognizes more than 90 nosological units with p
Externí odkaz:
https://doaj.org/article/89254536612c40e490eb8ff1a184d996
Autor:
Bokang Calvin Lenyeletse Maswabi, Jan Molinsky, Filipp Savvulidi, Tomas Zikmund, Dana Prukova, Diana Tuskova, Magdalena Klanova, Petra Vockova, Lucie Lateckova, Ludek Sefc, Jan Zivny, Marek Trneny, Pavel Klener
Publikováno v:
Haematologica, Vol 102, Iss 4 (2017)
Externí odkaz:
https://doaj.org/article/4939dddb976741d782de82c5c6d12687
Autor:
Lucie Lorkova, Michaela Scigelova, Tabiwang Ndipanquang Arrey, Ondrej Vit, Jana Pospisilova, Eliska Doktorova, Magdalena Klanova, Mahmudul Alam, Petra Vockova, Bokang Maswabi, Pavel Klener, Jiri Petrak
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135314 (2015)
Mantle cell lymphoma (MCL) is a chronically relapsing aggressive type of B-cell non-Hodgkin lymphoma considered incurable by currently used treatment approaches. Fludarabine is a purine analog clinically still widely used in the therapy of relapsed M
Externí odkaz:
https://doaj.org/article/934d78619f8049778d49fd8d7f250fbf
Publikováno v:
Case Reports in Immunology, Vol 2012 (2012)
Myelomatous pleural effusion (MPE) is an extremely rare manifestation of multiple myeloma (MM). We present a case of MPE in a patient with IgG-κ MM treated with intrapleural bortezomib with systemic bortezomib-based therapy. Although we observed goo
Externí odkaz:
https://doaj.org/article/c8067b2d623844a4b5bf0c5f202c7873
Autor:
Pavel Klener, Marek Trneny, Eva Fronkova, Adela Berkova, Petra Vockova, Mariana Pacheco-Blanco, Kristina Forsterova, Karel Helman, Eva Pokorna, Diana Tuskova, Zuzana Zemanova, Karla Svobodova, Jan Soukup, Ondrej Havranek, Magdalena Klanova, Michael Svaton, Jana Karolova, Zuzana Nahacka, Ladislav Andera, Dana Prukova
Purpose:Mantle cell lymphoma (MCL) is an aggressive subtype of B-cell non-Hodgkin lymphomas characterized by (over)expression of BCL2. A BCL2-targeting drug, venetoclax, has promising anticancer activity in MCL. We analyzed molecular mechanisms of ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f5c886ce44042199a0881ea8008748
https://doi.org/10.1158/1078-0432.c.6528017
https://doi.org/10.1158/1078-0432.c.6528017
Autor:
Pavel Klener, Marek Trneny, Robert Pytlik, Roman Kodet, Mahmudul Alam, Bokang Calvin Lenyeletse Maswabi, Jan Molinsky, Lucie Lateckova, Petra Vockova, Karel Helman, Radek Jaksa, Dana Vejmelkova, Dana Prukova, Jan Soukup, Simona Benesova, Jan Svadlenka, Jan Brazina, Ladislav Andera, Magdalena Klanova
Western blot analysis showing protein expression profile of key regulators of apoptosis in 18 DLBCL cell lines (12 germinal center B-cell-like (GCB) and 6 activated B-cell-like (ABC) DLBCL cell lines). *UPF4D cell line (GCB origin) was derived in our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c173972cf2e268702b74b82a1e49d1e3
https://doi.org/10.1158/1078-0432.22457130
https://doi.org/10.1158/1078-0432.22457130