Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Magdalena Kistowska"'
Autor:
Martin Kaul, Peter End, Maciej Cabanski, Carole Schuhler, Annamaria Jakab, Magdalena Kistowska, Arvind Kinhikar, Alessio Maiolica, Angela Sinn, Rainard Fuhr, Bruno Cenni
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1756-1768 (2021)
Abstract Safe and effective new oral therapies for autoimmune, allergic, and inflammatory conditions remain a significant therapeutic need. Here, we investigate the human pharmacokinetics, pharmacodynamics (PDs), and safety of the selective, covalent
Externí odkaz:
https://doaj.org/article/b831d07ed7124764bf42b3d566c92e8a
Autor:
Arvind Kinhikar, Angela Sinn, Alessio Maiolica, Rainard Fuhr, Annamaria Jakab, Martin Kaul, Carole Schuhler, Magdalena Kistowska, Peter End, Maciej Cabanski, Bruno Cenni
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 5, Pp 1756-1768 (2021)
Clinical and Translational Science, Vol 14, Iss 5, Pp 1756-1768 (2021)
Safe and effective new oral therapies for autoimmune, allergic, and inflammatory conditions remain a significant therapeutic need. Here, we investigate the human pharmacokinetics, pharmacodynamics (PDs), and safety of the selective, covalent Bruton
Autor:
Emmanuel Contassot, Lars E. French, Magdalena Kistowska, Tatiana Proust, Laurence Feldmeyer, Antonio Cozzio, Barbara Meier, Thomas Kuendig
Publikováno v:
Journal of Investigative Dermatology
Propionibacterium acnes is a Gram-positive commensal bacterium thought to be involved in the pathogenesis of acne vulgaris. Although the ability of P. acnes in the initiation of pro-inflammatory responses is well documented, little is known about ada
Autor:
Magdalena Kistowska, Gabriele Fenini, Dragana Jankovic, Laurence Feldmeyer, Katrin Kerl, Philipp Bosshard, Emmanuel Contassot, Lars E. French
Publikováno v:
Experimental Dermatology
Although being a normal part of the skin flora yeasts of the genus Malassezia are associated with several common dermatologic conditions including pityriasis versicolour seborrhoeic dermatitis (SD) folliculitis atopic eczema/dermatitis (AE/AD) and da
Autor:
Hans-Dietmar Beer, Lars E. French, Gabriel Sollberger, Magdalena Kistowska, Gerhard E. Strittmatter
Publikováno v:
Journal of immunology (Baltimore Md. : 1950)
IL-1β and IL-18 are crucial regulators of inflammation and immunity. Both cytokines are initially expressed as inactive precursors, which require processing by the protease caspase-1 for biological activity. Caspase-1 itself is activated in differen
Autor:
Gabriela Senti, Lars E. French, Pål Johansen, Hans-Dietmar Beer, Annette Oxenius, Emmanuel Contassot, Antonia Fettelschoss, Salomé LeibundGut-Landmann, Magdalena Kistowska, Martin F. Bachmann, Thomas M. Kündig
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Interleukin-1α (IL-1α) and -β both bind to the same IL-1 receptor (IL-1R) and are potent proinflammatory cytokines. Production of proinflammatory (pro)–IL-1α and pro–IL-1β is induced by Toll-like receptor (TLR)-mediated NF-κB activation. Ad
Autor:
Regine Landmann, Gennaro De Libero, Emmanuel Rossy, Lucia Mori, Sebastiano Sansano, Hans-Jürgen Gober, Magdalena Kistowska
Publikováno v:
European journal of immunology
Primates, but not rodents, have T cell receptor Vgamma9-Vdelta2 T cells bridging innate and adaptive antimicrobial immunity. This T cell population is activated by prenyl pyrophosphates isolated from microbial or eukaryotic cells. Although the microb
Autor:
Magdalena Kistowska, Samantha Paoletti, Vania Manolova, Lucia Mori, Daniel Hanau, Huguette Bausinger, Gabriel M. Baltariu, Gennaro De Libero
Publikováno v:
European Journal of Immunology. 36:1083-1092
Self-glycosphingolipids bind to surface CD1 molecules and are readily displaced by other CD1 ligands. This capacity to exchange antigens at the cell surface is not common to other antigen-presenting molecules and its physiological importance is uncle
Autor:
Lucia Mori, Paul Jenö, Lena Angman, Hans-Jürgen Gober, Magdalena Kistowska, Gennaro De Libero
Publikováno v:
The Journal of Experimental Medicine
T lymphocytes expressing the T cell receptor (TCR)-gammadelta recognize unknown antigens on tumor cells. Here we identify metabolites of the mevalonate pathway as the tumor ligands that activate TCR-gammadelta cells. In tumor cells, blockade of hydro
Autor:
Katrin Kerl, Emmanuel Contassot, Laurence Feldmeyer, Dragana Jankovic, Magdalena Kistowska, Philipp P. Bosshard, Lars E. French, Gabriele Fenini
Publikováno v:
Experimental dermatology. 23(12)
Although being a normal part of the skin flora, yeasts of the genus Malassezia are associated with several common dermatologic conditions including pityriasis versicolour, seborrhoeic dermatitis (SD), folliculitis, atopic eczema/dermatitis (AE/AD) an